DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

Issue 07 · Volume 78 · 1997 DOI: 10.1055/s-008-40700

Thrombosis in the young

  • 001
  • 007
  • 013
  • Gene therapy for hemophilia: hopes and reality for the children of the new century

  • 024
    Eisensmith, Randy C; Woo, Savio L C:

    Viral Vector-Mediated Gene Therapy for Hemophilia B

  • 031
    Connelly, Sheila; Kaleko, Michael:

    Gene Therapy for Hemophilia A

  • Thrombopoietin

  • 037
    Cohen-Solal, Karine; Debili, Najet; Vainchenker, William; Wendling, Françoise:

    Thrombopoietin (Mpl-ligand) and the Regulation of Platelet Production

  • 042
  • Hemostatic predictors of thrombosis: the contribution of epidemiology

  • 047
  • 053
  • Platelet-leukocyte-endothelial cell cross-talk

  • 060
    Frenette, Paul S; Wagner, Denisa D:

    Insights into Selectin Function from Knockout Mice

  • 065
  • The protein C pathway

  • 070
    Esmon, Charles T; Ding, Wei; Yasuhiro, Katsuura; Gu, Jian-Ming; Ferrell, Gary; Regan, Lisa M; Stearns-Kurosawa, Deborah J; Kurosawa, Shimichiro; Mather, Timothy; Laszik, Zolton; Esmon, Naomi L:

    The Protein C Pathway: New Insights

  • Antiphospholipid antibodies

  • 075
    Galli, Monica; Finazzi, Guido; Barbui, Tiziano:

    Antiphospholipid Antibodies: Predictive Value of Laboratory Tests

  • 079
    Esmon, Naomi L; Smirnov, Mikhail D; Esmon, Charles T:

    Thrombogenic Mechanisms of Antiphospholipid Antibodies

  • Integrin signalling and vascular function

  • 083
  • 088
  • 096
  • Understanding the initiation of blood coagulation

  • 101
  • 108
  • 112
    Morrissey, James H; Neuenschwander, Pierre F; Huang, Qiuling; McCallum, Christine D; Su, Bixia; Johnson, Arthur E:

    Factor VIIa-Tissue Factor: Functional Importance of Protein-Membrane Interactions

  • Venous thromboembolism and cancer, a two-way clinical association

  • 117
  • 121
    Prins, Martin H; Hettiarachchi, Rohan J K; Lensing, Anthonie W A; Hirsh, Jack:

    Newly Diagnosed Malignancy in Patients with VenousThromboembolism. Search or Wait and See?

  • 126
  • 133
  • 137
    Bona, Robert D; Hickey, Amy D; Wallace, Donna M:

    Efficacy and Safety of Oral Anticoagulation in Patients with Cancer

  • 141
  • Molecular defects in rare bleeding disorders

  • 145
  • 151
    Cooper, David N; Millar, David S; Wacey, Adam; Banner, David W; Tuddenham, Edward G D:

    Inherited Factor VII Deficiency: Molecular Genetics and Pathophysiology

  • 161
    Cooper, David N; Millar, David S; Wacey, Adam; Pemberton, Susan; Tuddenham, Edward G D:

    Inherited Factor X Deficiency: Molecular Genetics and Pathophysiology

  • Antithrombotic therapy of acute stroke

  • 173
    Samama, M M; Desnoyers, P C; Conard, J; Bousser, M G:

    Acute Ischemic Stroke and Heparin Treatments

  • 180
  • 183
  • Pathogenesis of atherosclerosis: a l997 update

  • 191
    Gryglewski, Ryszard J; Korbut, Ryszard; Uracz, Wojciech; Malinski, Tadeusz:

    Crossroads of L-Arginine/Arachidonate Metabolism

  • 195
    Berliner, Judith; Leitinger, Norbert; Watson, Andrew; Huber, Joakim; Fogelman, Alan; Navab, Mohamad:

    Oxidized Lipids in Atherogenesis: Formation, Destruction and Action

  • 200
    Taubman, Mark B; Fallon, John T; Schecter, Alison D; Giesen, Peter; Mendlowitz, Milton; Fyfe, Billie S; Marmur, Jonathan D; Nemerson, Yale:

    Tissue Factor in the Pathogenesis of Atherosclerosis

  • Clinical trials with anti IIb/IIIa inhibitors in acute coronary syndromes

  • 205
  • 210
  • 214
  • Platelets and signal transduction

  • 220
  • 226
    Levy-Toledano, Sylviane; Gallet, Carole; Nadal, Florence; Bryckaert, Marijke; Maclouf, Jacques; Rosa, Jean-Philippe:

    Phosphorylation and Dephosphorylation Mechanisms in Platelet Function: a Tightly Regulated Balance

  • 234
  • PLENARY LECTURE – Shirley Johnson Lecture

  • 242
  • PLENARY LECTURE – Marion Barnhart

  • 247
    Fuster, Valentin; Fallon, John T; Badimon, J J; Nemerson, Yale:

    The Unstable Atherosclerotic Plaque: Clinical Significance and Therapeutic Intervention

  • New recombinant products in the treatment of hemophilias

  • 256
  • 261
    White, Gilbert C; Beebe, Aime; Nielsen, Brenda:

    Recombinant Factor IX

  • Platelet membrane glycoproteins

  • 266
    Clemetson, Kenneth J:

    Platelet GPIb-V-IX Complex

  • 271
    Gachet, Christian; Hechlel, Béatrice; Léon, Catherine; Vial, Catherine; Leray, Claude; Ohlmann, Philippe; Cazenave, Jean-Pierre:

    Activation of ADP Receptors and Platelet Function

  • Current status of activation markers in ischemic heart disease

  • 276
  • 280
    FitzGerald, Garret A; Tigges, Jessica; Barry, Patricia; Lawson, John A:

    Markers of Platelet Activation and Oxidant Stress in Atherothrombotic Disease

  • Tumors and fibrinolysis

  • 285
    Schmitt, M; Harbeck, N; Thomssen, C; Wilhelm, O; Magdolen, V; Reuning, U; Ulm, K; Höfler, H; Jänicke, F; Graeff, H:

    Clinical Impact of the Plasminogen Activation System in Tumor Invasion and Metastasis: Prognostic Relevance and Target for Therapy

  • Thrombophilia as a multigenic disorder

  • 297
    Seligsohn, Uri; Zivelin, Ariella:

    Thrombophilia as a Multigenic Disorder

  • Leukocyte-endothelial cell interactions

  • 302
    Mclntyre, Thomas M; Modur, Vijayanand; Prescott, Stephen M; Zimmerman, Guy A:

    Molecular Mechanisms of Early Inflammation

  • 306
    Furie, Bruce; Furie, Barbara C:

    Leukocyte Crosstalk at the Vascular Wall

  • 310
  • Oral contraceptives and thrombotic disease

  • 315
  • 327
    Helmerhorst, F M; Bloemenkamp, K W M; Rosendaal, F R; Vandenbroucke, J P:

    Oral Contraceptives and Thrombotic Disease: Risk of Venous Thromboembolism

  • 334
  • Molecular basis of inherited thrombophilia: from genedefects to disease

  • 339
    Bayston, Trevor A; Lane, David A:

    Antithrombin: Molecular Basis of Deficiency

  • 344
  • 351
    Borgel, Delphine; Gandrille, Sophie; Aiach, Martine:

    Protein S Deficiency

  • Clinical trials of direct thrombin inhibitors

  • 357
  • 364
  • 367
    Hermann, Jean-Paul R; Kutryk, Michael J B; Serruys, Patrick W:

    Clinical Trials of Direct Thrombin Inhibitors During Invasive Procedures

  • Controversial issues in oral anticoagulant therapy

  • 377
    Koefoed, Birgitte Gade; Gulløv, Annette Lemche; Petersen, Palle:

    Prevention of Thromboembolic Events in Atrial Fibrillation

  • 382
  • Thrombomodulin

  • 386
    Nesheim, Michael; Wang, Wei; Boffa, Michael; Nagashima, Mariko; Morser, John; Bajzar, Laszlo:

    Thrombin, Thrombomodulin and TAFI in the Molecular Link Between Coagulation and Fibrinolysis

  • 392
  • 396
    Öhlin, Ann-K; Norlund, Lena; Marlar, Richard A:

    Thrombomodulin Gene Variations and Thromboembolic Disease

  • Cytokines and thrombosis

  • 401
  • 406
    Mantovani, Alberto; Sozzani, Silvano; Vecchi, Annunciata; Introna, Martino; Allavena, Paola:

    Cytokine Activation of Endothelial Cells: New Molecules for an Old Paradigm

  • 415
    ten Cate, Jan W; Poll, Tom van der; Levi, Marcel; Cate, Hugo ten; Deventer, Sander J H van:

    Cytokines: Triggers of Clinical Thrombotic Disease

  • PLENARY LECTURE – Sol Sherry Lecture

  • 420
    Vermylen, J; Hoylaerts, M F; Arnout, J:

    Antibody-Mediated Thrombosis

  • PLENARY LECTURE – Wright-Schulte Lecture

  • 427
  • Platelet activation by collagen

  • 434
    Sixma, Jan J; van Zanten, G Henrita; Huizinga, Eric G; van der Plas, R Martijn; Verkley, Marilyn; Wu, Ya-Ping; Gros, Piet; de Groot, Philip G:

    Platelet Adhesion to Collagen: an Update

  • 439
    Moroi, Masaaki; Jung, S M:

    Platelet Receptors for Collagen

  • Pathophysiology of von Willebrand factor

  • 445
    Rand, Jacob H; Glanville, Robert W; Wu, Xiao-Xuan; Ross, Julia M; Zangari, Maurizio; Gordon, Ronald E; Schwartz, Elaine; Potter, Barry J:

    The Significance of Subendothelial von Willebrand Factor

  • 451
    Meyer, D; Fressinaud, E; Gaucher, C; Lavergne, J-M; Hilbert, L; Ribba, A-S; Jorieux, S; Mazurier, C; INSERM Network on Molecular Abnormalities in von Willebrand Disease:

    Gene Defects in 150 Unrelated French Cases with Type 2 von Willebrand Disease: from the Patient to the Gene

  • Genetic determinants of the risk of arterial thrombosis

  • 457
  • 462
    Minno, Giovanni Di; Grandone, Elvira; Margaglione, Maurizio:

    Clinical Relevance of Polymorphic Markers of Arterial Thrombosis

  • Tissue factor pathway inhibitor: a protein in search for a disease

  • 467
  • 471
  • New aspects of APC resistance

  • 478
  • 483
  • Clinical use of low molecular weight heparins

  • 489
    Turkstra, Franktien; Koopman, Maira M W; Büller, Harry R:

    The Treatment of Deep Vein Thrombosis and Pulmonary Embolism

  • Metallo proteinases and vascular biology

  • 497
    Sato, Hiroshi; Okada, Yasunori; Seiki, Motoharu:

    Membrane-Type Matrix Metalloproteinases (MT-MMPs) in Cell Invasion

  • Crystal structure of coagulation proteins

  • 501
  • 512
  • 516
    Carrell, Robin; Skinner, Richard; Jin, Lei; Abrahams, Jan Pieter:

    Structural Mobility of Antithrombin and its Modulation by Heparin

  • Hyperhomocysteinemia and thrombosis

  • 520
  • 523
  • 527
  • Transgenic production of hemostasis proteins

  • 532
  • 537
    Butler, Stephen P; Cott, Kevin van; Subrumanian, Anuradha; Gwazduaskas, Francis C; Velander, William H:

    Current Progress in the Production of Recombinant Human Fibrinogen in the Milk of Transgenic Animals

  • 543
  • The drug trials that have influenced our clinical practice in the treatment of thrombosis

  • 548
  • 553
  • 558
  • New treatments of von Wiltebrand disease

  • 562
  • 566
  • 571
    Schwarz, Hans Peter; Turecek, Peter L; Pichler, Ludwig; Mitterer, Artur; Mundt, Wolfgang; Dorner, Friedrich; Roussi, Jacqueline; Drouet, Ludovic:

    Recombinant von Willebrand Factor

  • Thrombin and its modulation

  • 577
  • 581
    Brass, Lawrence F; Manning, David R; Cichowski, Karen; Abrams, Charles S:

    Signaling through G Proteins in Platelets: to the Integrins and Beyond

  • 590
  • Structure and mechanism of action of vitamin K-dependent gamrnt-ctrboxylase

  • 595
  • 599
    Stafford, Darrel W; Wu, S M; Stanley, Thomas B; Mutucumarana, Vasantha P:

    Characterization of the ϒ-Glutamyl Carboxylase

  • Plenary Lecture

  • 605
  • 611
  • Bleeding and thrombosis in myeloproliferative disorders

  • 617
    Landolfi, Raffaele; Marchioli, Roberto; Patrono, Carlo:

    Mechanisms of Bleeding and Thrombosis in Myeloproliferative Disorders

  • 622
  • New aspects of arachidonic acid metabolism

  • 627
    Smith, William L; DeWitt, David L; Arakawa, Toshiya; Spencer, Andrew G; Thuresson, Elizabeth D; Song, Inseok:

    Independent Prostanoid Biosynthetic Systems Associated with Prostaglandin Endoperoxide Synthases-1 and -2

  • Epidemiology of inherited thrombophilia

  • 631
    Meer, Felix J M van der; Koster, T; Vandenbroucke, J P; Briët, E; Rosendaal, Frits R:

    The Leiden Thrombophilia Study (LETS)

  • 636
  • Factor VIII and factor IX inhibitors

  • 641
    Gilles, Jean Guy G; Jacquemin, Marc G; Saint-Remy, Jean-Marie R:

    Factor VIII Inhibitors

  • 647
  • Plasminogen activator inhibitor I (PAI-1)

  • 652
  • 656
  • Special Symposium

  • 661
    Martinowitz, Uri; Spotnitz, William D:

    Fibrin Tissue Adhesives

  • Animal models of thrombotic and hemorrhagic disorders

  • 667
  • Angiogenesis

  • 672
  • 678
    Breier, Georg; Damert, Annette; Plate, Karl H; Risau, Werner:

    Angiogenesis in Embryos and Ischemic Diseases

  • Prevention and treatment of deep vein thrombosis

  • 684
  • 689
  • 693
  • Lessons from gene knock-out technology

  • 699
  • 705
  • Disorders of hemostasis in childhood

  • 710
  • 715
    Andrew, Maureen; David, Michelle; deVeber, Gabrielle; Brooker, Lu Ann:

    Arterial Thromboembolic Complications in Paediatric Patients

  • 726
  • Newer antithrombotic agents

  • 730
  • 736
  • 742
    Collen, Désiré:

    Thrombolytic Therapy

  • Tissue factor

  • 747
  • 755
  • 759
    Semeraro, Nicola; Colucci, Mario:

    Tissue Factor in Health and Disease

  • Hormone replacement therapy in postmenopausal women and cardiovascular risk

  • 765
  • 770
    Chae, Claudia U; Ridker, Paul M; Manson, JoAnn E:

    Postmenopausal Hormone Replacement Therapy and Cardiovascular Disease