DOI: 10.1055/s-00035024

Thrombosis and Haemostasis

eFirst

Publication Date: 17 September 2020

Invited Editorial Focus

Pandey, Arjun K.; Eikelboom, John W.: Direct Oral Anticoagulant Dosing in Extremes of Body Weight: Time to Revisit the Guidelines?

Invited Editorial Focus

Polzin, Amin; Dannenberg, Lisa; Thienel, Manuela; Orban, Martin; Wolff, Georg; Hohlfeld, Thomas; Zeus, Tobias; Kelm, Malte; Petzold, Tobias: Noncanonical Effects of Oral Thrombin and Factor Xa Inhibitors in Platelet Activation and Arterial Thrombosis

Publication Date: 15 September 2020

Letter to the Editor

Jourdi, Georges; Lobies, Sophie; Kosmider, Olivier; Duchemin, Jérôme; Audureau, Etienne; Conard, Jacqueline; Mazoyer, Elisabeth; Horellou, Marie-Hélène; Gouin-Thibault, Isabelle; Flaujac, Claire; Fontenay, Michaëla: Coagulation Characterization of Prothrombin 20209C > T Variant: About 27 New Cases
Supplementary Material

Stroke, Systematic or Venous Thromboembolism

Murphy, Stephen J. X.; Lim, Soon Tjin; Hickey, Fionnuala; Kinsella, Justin A.; Smith, Deirdre R.; Tierney, Sean; Egan, Bridget; Feeley, T. Martin; Murphy, Sinéad M.; Collins, D. Rónán; Coughlan, Tara; O'Neill, Desmond; Harbison, Joseph A.; Madhavan, Prakash; O'Neill, Sean M.; Colgan, Mary-Paula; O'Donnell, James S.; O'Sullivan, Jamie M.; Hamilton, George; McCabe, Dominick J. H.: von Willebrand Factor Antigen, von Willebrand Factor Propeptide, and ADAMTS13 in Carotid Stenosis and Their Relationship with Cerebral Microemboli

Publication Date: 13 September 2020

Atherosclerosis and Ischaemic Disease

Yamashita, Atsushi; Nishihira, Kensaku; Gi, Toshihiro; Maekawa, Kazunari; Hatakeyama, Kinta; Horiuchi, Saki; Wada, Kei; Shibata, Yoshisato; Asada, Yujiro: Pathological Features of Ruptured Coronary Plaque and Thrombus Interfaces: Fibrin and von Willebrand Factor as Platelet Scaffolds on Rupture Sites
Supplementary Material

Coagulation and Fibrinolysis

Bertaggia Calderara, Debora; Zermatten, Maxime G.; Aliotta, Alessandro; Batista Mesquita Sauvage, Ana P.; Carle, Vanessa; Heinis, Christian; Alberio, Lorenzo: Tissue Factor-Independent Coagulation Correlates with Clinical Phenotype in Factor XI Deficiency and Replacement Therapy
Supplementary Material

Coagulation and Fibrinolysis

Boriani, Giuseppe; Ruff, Christian T.; Kuder, Julia F.; Shi, Minggao; Lanz, Hans J.; Antman, Elliott M.; Braunwald, Eugene; Giugliano, Robert P.: Edoxaban versus Warfarin in Patients with Atrial Fibrillation at the Extremes of Body Weight: An Analysis from the ENGAGE AF-TIMI 48 Trial
Supplementary Material

Coagulation and Fibrinolysis

Orlando, Christelle; de la Morena-Barrio, Belén; Pareyn, Inge; Vanhoorelbeke, Karen; Martínez-Martínez, Irene; Vicente, Vicente; Corral, Javier; Jochmans, Kristin; de la Morena-Barrio, Maria Eugenia: Antithrombin p.Thr147Ala: The First Founder Mutation in People of African Origin Responsible for Inherited Antithrombin Deficiency
Supplementary Material

Invited Editorial Focus

Drouet, Ludovic; Harenberg, Job; Torri, Giangiacomo: The Multiple Faces of Heparin: Opportunities in COVID-19 Infection and Beyond

Position Paper

Gerotziafas, Grigoris T.; Catalano, Mariella; Colgan, Mary-Paula; Pecsvarady, Zsolt; Wautrecht, Jean Claude; Fazeli, Bahare; Olinic, Dan-Mircea; Farkas, Katalin; Elalamy, Ismail; Falanga, Anna; Fareed, Jawed; Papageorgiou, Chryssa; Arellano, Rosella S.; Agathagelou, Petros; Antic, Darco; Auad, Luciana; Banfic, Ljiljana; Bartolomew, John R.; Benczur, Bela; Bernardo, Melissa B.; Boccardo, Francesco; Cifkova, Renate; Cosmi, Benilde; De Marchi, Sergio; Dimakakos, Evangelos; Dimopoulos, Meletios A.; Dimitrov, Gabriel; Durand-Zaleski, Isabelle; Edmonds, Michael; El Nazar, Essam Abo; Erer, Dilek; Esponda, Omar L.; Gresele, Paolo; Gschwandtner, Michael; Gu, Yongquan; Heinzmann, Mónica; Hamburg, Naomi M.; Hamadé, Amer; Jatoi, Noor-Ahmed; Karahan, Oguz; Karetova, Debora; Karplus, Thomas; Klein-Weigel, Peter; Kolossvary, Endre; Kozak, Matija; Lefkou, Eleftheria; Lessiani, Gianfranco; Liew, Aaron; Marcoccia, Antonella; Marshang, Peter; Marakomichelakis, George; Matuska, Jiri; Moraglia, Luc; Pillon, Sergio; Poredos, Pavel; Prior, Manlio; Salvador, David Raymund K.; Schlager, Oliver; Schernthaner, Gerit; Sieron, Alexander; Spaak, Jonas; Spyropoulos, Alex; Sprynger, Muriel; Suput, Dusan; Stanek, Agata; Stvrtinova, Viera; Szuba, Andrzej; Tafur, Alfonso; Vandreden, Patrick; Vardas, Panagiotis E.; Vasic, Dragan; Vikkula, Miikka; Wennberg, Paul; Zhai, Zhenguo; Scientific Reviewer Committee Guidance for the Management of Patients with Vascular Disease or Cardiovascular Risk Factors and COVID-19: Position Paper from VAS-European Independent Foundation in Angiology/Vascular Medicine

Publication Date: 09 September 2020

Coagulation and Fibrinolysis

Taniguchi, Kohei; Ohbe, Hiroyuki; Yamakawa, Kazuma; Matsui, Hiroki; Fushimi, Kiyohide; Yasunaga, Hideo: Recombinant Thrombomodulin in Disseminated Intravascular Coagulation Associated with Stage IV Solid Tumors: A Nationwide Observational Study in Japan
Supplementary Material

Coagulation and Fibrinolysis

Yaoi, Hiroaki; Shida, Yasuaki; Kitazawa, Takehisa; Shima, Midori; Nogami, Keiji: Emicizumab Augments Thrombus Formation in Whole Blood from Patients with Hemophilia A under High Shear Flow Conditions

T&H Insights

Ni, Heyu: Antithrombotics from Frog Skin Secretions

Publication Date: 02 September 2020

Cellular Haemostasis and Platelets

Hsu, Ling-Wei; Chen, Po-Wei; Chang, Wei-Ting; Lee, Wen-Huang; Liu, Ping-Yen: The Role of ROCK in Platelet–Monocyte Collaborative Induction of Thromboinflammation during Acute Coronary Syndrome
Supplementary Material

Coagulation and Fibrinolysis

van Paridon, Pauline C. S.; Panova-Noeva, Marina; van Oerle, Rene; Schulz, Andreas; Prochaska, Jürgen H.; Arnold, Natalie; Schmidtmann, Irene; Beutel, Manfred; Pfeiffer, Norbert; Münzel, Thomas; Lackner, Karl J.; Hackeng, Tilman M.; ten Cate, Hugo; Wild, Philipp S.; Spronk, Henri M. H.: Relation between Tissue Factor Pathway Inhibitor Activity and Cardiovascular Risk Factors and Diseases in a Large Population Sample

New Technologies, Diagnostic Tools and Drugs

Maji, Debnath; Opneja, Aman; Suster, Michael A.; Bane, Kara L.; Wilson, Brigid M.; Mohseni, Pedram; Stavrou, Evi X.: Monitoring DOACs with a Novel Dielectric Microsensor: A Clinical Study
Supplementary Material

Stroke, Systemic or Venous Thromboembolism

Leventis, Ioannis A.; Sagris, Dimitrios; Strambo, Davide; Perlepe, Kalliopi; Sirimarco, Gaia; Nannoni, Stefania; Korompoki, Eleni; Manios, Efstathios; Makaritsis, Konstantinos; Vemmos, Konstantinos; Michel, Patrik; Ntaios, George: Atrial Cardiopathy and Likely Pathogenic Patent Foramen Ovale in Embolic Stroke of Undetermined Source

Stroke, Systemic or Venous Thromboembolism

Picker, Nils; Lee, Agnes Y.; Cohen, Alexander T.; Maraveyas, Anthony; Beyer-Westendorf, Jan; Mantovani, Lorenzo G.; Abdelgawwad, Khaled; Fatoba, Samuel; Thate-Waschke, Inga-Marion; Bach, Miriam; Wilke, Thomas: Anticoagulation Treatment in Cancer-Associated Venous Thromboembolism: Assessment of Patient Preferences Using a Discrete Choice Experiment (COSIMO Study)
Supplementary Material

Publication Date: 01 September 2020

Letter to the Editor

Eriksson, Oskar; Hultström, Michael; Persson, Barbro; Lipcsey, Miklos; Ekdahl, Kristina Nilsson; Nilsson, Bo; Frithiof, Robert: Mannose-Binding Lectin is Associated with Thrombosis and Coagulopathy in Critically Ill COVID-19 Patients

Publication Date: 30 August 2020

Coagulation and Fibrinolysis

Yan, Lufeng; Zhu, Mengshan; Wang, Danli; Tao, Wenyang; Liu, Donghong; Zhang, Fuming; Linhardt, Robert J.; Ye, Xingqian; Chen, Shiguo: Oral Administration of Fucosylated Chondroitin Sulfate Oligomers in Gastro-Resistant Microcapsules Exhibits a Safe Antithrombotic Activity
Supplementary Material

Invited Clinical Focus

Mandrola, John M.; Kaul, Sanjay; Foy, Andrew: Lessons Learnt from Recent Trials in Ischemic Heart Disease

Letter to the Editor

Bhoelan, B. Soerajja; Mulder, René; Lukens, Michaël V.; Meijer, Karina: Direct Oral Anticoagulants in Antithrombin Deficiency: Initial Experience in a Single Center

Letter to the Editor

Marchandot, Benjamin; Trimaille, Antonin; Curtiaud, Anaïs; Carmona, Adrien; Matsushita, Kensuke; Sato, Chisato; Leonard-Lorant, Ian; Sattler, Laurent; Grunebaum, Lelia; Ohana, Mickaël; Ohlmann, Patrick; Jesel, Laurence; Morel, Olivier: Staging Severity of COVID-19 according to Hemostatic Abnormalities (CAHA Score)

Stroke, Systemic or Venous Thromboembolism

Martin, Anne Céline; Thomas, William; Mahir, Zahra; Crowley, Maeve P.; Dowling, Terry; Breen, Karen; Collings, Victoria; Moore, Gary W.; MacDonald, Stephen; Hunt, Beverley J.; Cohen, Alexander T.: Direct Oral Anticoagulant Concentrations in Obese and High Body Weight Patients: A Cohort Study

Publication Date: 27 August 2020

Cellular Haemostasis and Platelets

Zhang, Jianjun; Zhang, Yan; Zheng, Shuang; Liu, Yangyang; Chang, Lin; Pan, Guanxing; Hu, Liang; Zhang, Si; Liu, Junling; Kim, Soochong; Dong, Jianzeng; Ding, Zhongren: PAK Membrane Translocation and Phosphorylation Regulate Platelet Aggregation Downstream of Gi and G12/13 Pathways
Supplementary Material

New Technologies, Diagnostic Tools and Drugs

Toorop, Myrthe M. A.; van Rein, Nienke; Cannegieter, Suzanne C.; van der Meer, Felix J. M.; Reitsma, Pieter H.; Lijfering, Willem M.; Bos, Mettine H. A.: High Soluble Thrombomodulin Is Associated with an Increased Risk of Major Bleeding during Treatment with Oral Anticoagulants: A Case–Cohort Study
Supplementary Material

Publication Date: 24 August 2020

Coagulation and Fibrinolysis

Sokou, Rozeta; Piovani, Daniele; Konstantinidi, Aikaterini; Tsantes, Andreas G.; Parastatidou, Stavroula; Lampridou, Maria; Ioakeimidis, Georgios; Gounaris, Antonis; Iacovidou, Nicoletta; Kriebardis, Anastasios G.; Politou, Marianna; Kopterides, Petros; Bonovas, Stefanos; Tsantes, Argirios E.: A Risk Score for Predicting the Incidence of Hemorrhage in Critically Ill Neonates: Development and Validation Study
Supplementary Material

Review Article

Katneni, Upendra K.; Alexaki, Aikaterini; Hunt, Ryan C.; Schiller, Tal; DiCuccio, Michael; Buehler, Paul W.; Ibla, Juan C.; Kimchi-Sarfaty, Chava: Coagulopathy and Thrombosis as a Result of Severe COVID-19 Infection: A Microvascular Focus

Review Article

Potpara, Tatjana S.; Lip, Gregory Y. H.; Blomstrom-Lundqvist, Carina; Boriani, Giuseppe; Van Gelder, Isabelle C.; Heidbuchel, Hein; Hindricks, Gerhard; Camm, Alan John: The 4S-AF Scheme (Stroke Risk; Symptoms; Severity of Burden; Substrate): A Novel Approach to In-Depth Characterization (Rather than Classification) of Atrial Fibrillation

Publication Date: 22 August 2020

Coagulation and Fibrinolysis

Shimonishi, Naruto; Ogiwara, Kenichi; Oda, Yukio; Kawabe, Toshiki; Okazaki, Shinji; Shima, Midori; Nogami, Keiji: A Novel Assessment of Factor VIII Activity by Template Matching Utilizing Weighted Average Parameters from Comprehensive Clot Waveform Analysis

Letter to the Editor

Patell, Rushad; Midha, Shonali; Kimani, Stephen; Martin, Richard; Neparidze, Natalia; Jaglal, Michael; Freed, Jason; Key, Nigel S.: Variability in Institutional Guidance for COVID-19-Associated Coagulopathy in the United States

Stroke, Systemic or Venous Thromboembolism

Kuczmik, Wiktoria; Wysokinski, Waldemar E.; Hesley, Gina K.; Vlazny, Danielle T.; Houghton, Damon E.; Swanson, Keith E.; Casanegra, Ana I.; Hodge, David; White, Launia; McBane, Robert D.: Calf Vein Thrombosis Comparison of Outcomes for Axial and Muscular Venous Thrombosis

Stroke, Systemic or Venous Thromboembolism

Lother, Achim; Kaier, Klaus; Ahrens, Ingo; Bothe, Wolfgang; Wolf, Dennis; Zehender, Manfred; Bode, Christoph; von zur Mühlen, Constantin; Stachon, Peter: Bleeding Complications Drive In-Hospital Mortality of Patients with Atrial Fibrillation after Transcatheter Aortic Valve Replacement

Publication Date: 20 August 2020

Coagulation and Fibrinolysis

Schreuder, Mark; Poenou, Geraldine; Strijbis, Viola J. F.; Cheung, Ka Lei; Reitsma, Pieter H.; Bos, Mettine H. A.: Evolutionary Adaptations in Pseudonaja Textilis Venom Factor X Induce Zymogen Activity and Resistance to the Intrinsic Tenase Complex
Supplementary Material

Review Article

Beurskens, Danielle M.H.; Huckriede, Joram P.; Schrijver, Roy; Hemker, H. Coenraad; Reutelingsperger, Chris P.; Nicolaes, Gerry A. F.: The Anticoagulant and Nonanticoagulant Properties of Heparin

Publication Date: 15 August 2020

New Technologies, Diagnostic Tools, and Drugs

de Jong, Annika; Dirven, Richard J.; Boender, Johan; Atiq, Ferdows; Anvar, Seyed Yahya; Leebeek, Frank W. G.; van Vlijmen, Bart J. M.; Eikenboom, Jeroen: Ex vivo Improvement of a von Willebrand Disease Type 2A Phenotype Using an Allele-Specific Small-Interfering RNA
Supplementary Material

Publication Date: 13 August 2020

Coagulation and Fibrinolysis

Strålfors, Annelie; Mikovic, Danijela; Schmidt, David; Onelöv, Liselotte; Soutari, Nida Mahmoud Hourani; Berndtson, Maria; Chaireti, Roza; Holmström, Margareta; Antovic, Jovan P.; Bruzelius, Maria: Genetics and Hemostatic Potential in Persons with Mild to Moderate Hemophilia A with a Discrepancy between One-Stage and Chromogenic FVIII Assays
Supplementary Material

Publication Date: 09 August 2020

Cellular Haemostasis and Platelets

Bärnthaler, Thomas; Mahla, Elisabeth; Toth, Gabor G.; Schuligoi, Rufina; Prüller, Florian; Buschmann, Eva; Heinemann, Akos: Supplemental Fibrinogen Restores Platelet Inhibitor-Induced Reduction in Thrombus Formation without Altering Platelet Function: An In Vitro Study

Coagulation and Fibrinolysis

Jhang, Won Kyoung; Park, Seong Jong: Evaluation of Disseminated Intravascular Coagulation in Critically Ill Pediatric Hemato-oncology Patients with Septic Shock

Letter to the Editor

Chatzigeorgiou, Antonios; Mitroulis, Ioannis; Chrysanthopoulou, Akrivi; Legaki, Aigli-Ioanna; Ritis, Konstantinos; Tentolouris, Nikolaos; Protogerou, Athanase D.; Koutsilieris, Michael; Sfikakis, Petros P.: Increased Neutrophil Extracellular Traps Related to Smoking Intensity and Subclinical Atherosclerosis in Patients with Type 2 Diabetes
Supplementary Material

Letter to the Editor

Xin, Li; Sun, Shusen; Wang, Jinwen; Lu, Wenchao; Wang, Tiansheng; Tang, Huilin: Dipeptidyl Peptidase 4 Inhibitors and Venous Thromboembolism Risk in Patients with Type 2 Diabetes: A Meta-analysis of Cardiovascular Outcomes Trials

Review Article

Kessler, Thorsten; Schunkert, Heribert; von Hundelshausen, Philipp: Novel Approaches to Fine-Tune Therapeutic Targeting of Platelets in Atherosclerosis: A Critical Appraisal
Supplementary Material

Publication Date: 03 August 2020

Coagulation and Fibrinolysis

de Jager, Nico C. B.; Heijdra, Jessica M.; Kieboom, Quincy; Kruip, Marieke J. H. A.; Leebeek, Frank W. G.; Cnossen, Marjon H.; Mathôt, Ron A. A.; for the OPTI-CLOT Group: Population Pharmacokinetic Modeling of von Willebrand Factor Activity in von Willebrand Disease Patients after Desmopressin Administration
Supplementary Material

Stroke, Systemic or Venous Thromboembolism

Gi, Toshihiro; Kuroiwa, Yasuyoshi; Yamashita, Atsushi; Mizutani, Yuko; Asanuma, Taketoshi; Miyati, Tosiaki; Maekawa, Kazunari; Aman, Murasaki; Imamura, Takuroh; Asada, Yujiro: High Signal Intensity on Diffusion-Weighted Images Reflects Acute Phase of Deep Vein Thrombus
Supplementary Material

Publication Date: 29 July 2020

Coagulation and Fibrinolysis

Garcia-Martínez, Iris; Borràs, Nina; Martorell, Marta; Parra, Rafael; Altisent, Carme; Ramírez, Lorena; Álvarez-Román, Maria Teresa; Nuñez, Ramiro; Megias-Vericat, Juan Eduardo; Corrales, Irene; Alonso, Sofia; Vidal, Francisco: Common Genetic Variants in ABO and CLEC4M Modulate the Pharmacokinetics of Recombinant FVIII in Severe Hemophilia A Patients
Supplementary Material

Publication Date: 27 July 2020

Cellular Haemostasis and Platelets

Scavone, Mariangela; Rizzo, Jessica; Femia, Eti A.; Podda, Gian Marco; Bossi, Elena; Caberlon, Sabrina; Paroni, Rita; Cattaneo, Marco: Patients with Essential Thrombocythemia may be Poor Responders to Enteric-Coated Aspirin, but not to Plain Aspirin

Cellular Haemostasis and Platelets

Shen, Chuanbin; Liu, Ming; Tian, Huiwen; Li, Jiameng; Xu, Runjia; Mwangi, James; Lu, Qiumin; Hao, Xue; Lai, Ren: Conformation-Specific Blockade of αIIbβ3 by a Non-RGD Peptide to Inhibit Platelet Activation without Causing Significant Bleeding and Thrombocytopenia
Supplementary Material

Coagulation and Fibrinolysis

Abrahami, Devin; Renoux, Christel; Yin, Hui; Fournier, Jean-Pascal; Azoulay, Laurent: The Association between Oral Anticoagulants and Cancer Incidence among Individuals with Nonvalvular Atrial Fibrillation
Supplementary Material

Invited Clinical Focus

Ding, Wern Yew; Mandrola, John; Gupta, Dhiraj: Left Atrial Appendage Occlusion: Past, Present and Future

Review Article

Gelbenegger, Georg; Schoergenhofer, Christian; Knoebl, Paul; Jilma, Bernd: Bridging the Missing Link with Emicizumab: A Bispecific Antibody for Treatment of Hemophilia A

Stroke, Systemic or Venous Thromboembolism

Elgendy, Islam Y.; Fogerty, Annemarie; Blanco-Molina, Ángeles; Rosa, Vladimir; Schellong, Sebastian; Skride, Andris; Portillo, José; Lopez-Miguel, Patricia; Monreal, Manuel; Weinberg, Ido: Clinical Characteristics and Outcomes of Women Presenting with Venous Thromboembolism during Pregnancy and Postpartum Period: Findings from the RIETE Registry
Supplementary Material

Publication Date: 24 July 2020

Review Article

Fernando, Himawan; McFadyen, James D.; Palasubramaniam, Jathushan; Shaw, James; Wang, Xiaowei; Stub, Dion; Peter, Karlheinz: Antithrombotic Therapy in Myocardial Infarction: Historic Perils and Current Challenges—A 70-Year Journey

Publication Date: 23 July 2020

Letter to the Editor

Boscolo, Annalisa; Spiezia, Luca; Correale, Christelle; Sella, Nicolò; Pesenti, Elisa; Beghetto, Luca; Campello, Elena; Poletto, Francesco; Cerruti, Lorenzo; Cola, Marco; De Cassai, Alessandro; Pasin, Laura; Eugenio, Serra; Vettor, Roberto; Cattelan, Anna Maria; Simioni, Paolo; Navalesi, Paolo: Different Hypercoagulable Profiles in Patients with COVID-19 Admitted to the Internal Medicine Ward and the Intensive Care Unit
Supplementary Material

Publication Date: 21 July 2020

New Technologies, Diagnostic Tools and Drugs

Chayoua, Walid; Yin, Dong-mei; Kelchtermans, Hilde; Moore, Gary W.; Gris, Jean-Christophe; Musiał, Jacek; Zuily, Stéphane; ten Cate, Hugo; de Laat, Bas; Devreese, Katrien M. J.: Is There an Additional Value in Detecting Anticardiolipin and Anti-β2 glycoprotein I IgA Antibodies in the Antiphospholipid Syndrome?
Supplementary Material

Publication Date: 17 July 2020

Coagulation and Fibrinolysis

Jin, Shanen; Jin, Yiyang; Xu, Bai; Hong, Jun; Yang, Xianghong: Prevalence and Impact of Coagulation Dysfunction in COVID-19 in China: A Meta-Analysis
Supplementary Material

Letter to the Editor

Chaudhary, Rahul; Kreutz, Rolf P.; Bliden, Kevin P.; Tantry, Udaya S.; Gurbel, Paul A.: Personalizing Antithrombotic Therapy in COVID-19: Role of Thromboelastography and Thromboelastometry

Letter to the Editor

Vaughan, Carl J.; Cronin, Heather; Ryan, Paul MacDaragh; Caplice, Noel M.: Obesity and COVID-19: A Virchow's Triad for the 21st Century