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Thromb Haemost 1997; 78(01): 083-087
DOI: 10.1055/s-0038-1657506
DOI: 10.1055/s-0038-1657506
Integrin signalling and vascular function
Targeted Mutations in Integrins and their Ligands: Their Implications for Vascular Biology
Authors
Further Information
Publication History
Publication Date:
12 July 2018 (online)
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References
- 1 Hynes RO, and Lander AD. 1992; Contact and adhesive specificities in the associations, migrations, and targeting of cells and axons. Cell 68: 303-322
- 2 Hynes RO. 1992; Integrins: versatility, modulation and signalling in cell adhesion. Cell 69: 11-25
- 3 Springer TA. 1994; Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 76: 301-314
- 4 McEver RP, Moore KL, and Cummings RD. 1995; Leukocyte trafficking mediated by selectin-carbohydrate interactions. J.Biol.Chem 270: 11025-11028
- 5 Tedder TF. 1995; The selectins: vascular adhesion molecules. FASEB J. 9: 866-873
- 6 Hynes RO. 1996; Targeted mutations in cell adhesion genes: what have we learned from them? Dev. Biol 180: 402-412
- 7 Fässler R, Georges-Labouesse E, Hirsch E. 1996; Genetic analyses of integrin function in mice. Curr.Opin Cell Biol 8: 641-646
- 8 Piali L, Hammel R, Uherek C, Bachmann F, Gisler RH, Dunon D, Imohof BA. 1995; CD31/PECAM-1 is a ligand for αvβ3 integrin involved in adhesion of leukocytes to endothelium. J.Cell Biol 130: 451-460
- 9 Cepek KL, Shaw SK, Parker CM, Russell GJ, Morrow JS, Rimm DL, and Brenner MB. 1994; Adhesion between epithelial cells and T lymphocytes mediated by E-cadherin and the αEβ7 integrin. Nature 372: 190-193
- 10 Karecla PI, Bowden SJ, Green SJ, and Kilshaw PJ. 1995; Recognition of E-cadherin on epithelial cells by the mucosal T cell integrin αM290β7 (αEβ7). Eur.J.Immunol 25: 852-856
- 11 Shattil SJ. 1995; Function and regulation of the b3 integrins in hemostasis and vascular biology. Thromb.Haem 74: 149-155
- 12 Ruoslahti E. 1996; RGD and other recognition sequences for integrins. Annu.Rev.Cell Dev.Biol 12: 697-715
- 13 Anderson DC, and Springer TA. 1987; Leukocyte adhesion deficiency: an inherited defect in the Mac-1, LFA-1, and pl50,95 glycoproteins. Ann.Rev.Medicine 38: 175-194
- 14 Nieuwenhuis HK, Akkerman JW N, Houdijk WP M, and Sixma JJ. 1985; Human blood platelets showing no response to collagen fail to express surface glycoprotein la. Nature 318: 470-472
- 15 Sadler JE, Matsushita T, Dong Z, Tuley EA, and Westfield LA. 1995; Molecular mechanism and classification of von Willebrand disease. Throm.and Haem 74: 161-166
- 16 George EL, Georges-Labouesse EN, Patel-King RS, Rayburn H, and Hynes RO. 1993; Defects in mesoderm, neural tube and vascular development in mouse embryos lacking fibronectin. Development 119: 1079-1091
- 17 Georges-Labouesse EN, George EL, Rayburn H, and Hynes RO. 1996; Mesodermal development in murine embryos mutated in the fibronectin gene. Dev.Dyn 207: 145-156
- 18 George EL, Baldwin S, and Hynes RO. Fibronectins are essential for heart and blood vessel morphogenesis, but are dispensible for initial specification of precursor cells, (submitted).
- 19 Yang JT, Rayburn H, and Hynes RO. 1993; Embryonic mesodermal defects in α5-integrin-deficient mice. Development 119: 1093-1105
- 20 Yang JT, and Hynes RO. 1996; Fibronectin receptor functions in embryonic cells deficient in α5β1 integrin can be replaced by αv integrins. Mol.Biol.Cell 7: 1737-1748
- 21 Varner JA, Brooks PC, and Cheresh DA. 1995; Review: The integrin αvβ3: angiogenesis and apoptosis. Cell Adh.Commun 3: 367-374
- 22 Dameron KM, Volpert OV, Tainsky MA, Bouck N. 1994; Control of angiogenesis in fibroblasts by regulation of thrombospondin-1. Science 265: 1582-1585
- 23 Roberts DD. 1996; Regulation of tumor growth and metastasis by thrombospondin-1. FASEB.J 10: 1183-1191
- 24 Stellmach V, Volpert OV, Crawford SE, Lawler J, Hynes RO, and Bouck N. 1997; Tumor suppressor genes and angiogenesis: the role of TP53 in fibroblasts. Eur.J.Cancer 32A: 2394-2400
- 25 Yang JT, Rayburn H, and Hynes RO. 1995; Cell adhesion events mediated by a4 integrins are essential in placental and cardiac development. Development 121: 549-560
- 26 Kwee L, Baldwin S, Stewart CS, Buck C, and Labow MA. 1995; Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1 deficient mice. Development 121: 489-503
- 27 Gurtner GC, Davis V, Li H, McCoy MJ, Sharp A, and Cybulsky MI. 1995; Targeted disruption of the murine VCAM-1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation. Genes and Dev 9: 01-14
- 28 Wagner N, Lvhler J, Kunkel EJ, Ley K, Leung E, Krissansen G, Rajewsky K, and Miller W. 1996; Essential role for β7 integrins in the formation of the gut associated lymphoid tissue. Nature 382: 366-370
- 29 Schön MP, Grusby MJ, Murphy EA, Adams CM, Donohue JP, Arya A, Agace WW, Brenner MB, and Parker CM. 1997 Integrin αE (CD103) mediates mucosal T cell localization and the generation of intestinal inflammation, (submitted).
- 30 Arroyo AG, Yang JT, Rayburn H, and Hynes RO. 1996; Differential requirements for α4 integrins during fetal and adult hematopoiesis. Cell 85: 0997-1008
- 31 Hirsch E, Iglesias A, Potocnik AJ, Hartmann U, and Fässler R. 1996; Impaired migration but not differentiation of haematopoietic stem cells in the absence of β1 integrins. Nature 380: 171-175
- 32 Wilson RW, Ballantyne CM, Smith SW, Montgomery C, Bradley A, O’Brien WE, and Beuadet AL. 1993; Gene targeting yields a CD18-mutant mouse for study of inflammation. J.Immunol 151: 1571-1578
- 33 Sligh JE, Ballantyne Jr CM, Rich SS, Hawkins HK, Smith CW, Bradley A, and Beaudet AL. 1993; Inflammatory and immune responses are impaired in mice deficient in intercellular adhesion molecule 1. Proc.Natl.Acad.Sci.USA 90: 8529-8533
- 34 Xu H, Gonzalo JA, St PierreY, Williams IR, Kupper TS, Cotran RS, Springer TA, and Gutierrez-Ramos JC. 1994; Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice. J.Exp.Med 180: 095-109
- 35 King PD, Sandberg ET, Selvakumar A, Fang P, Beaudet AL, and Dupont B. 1995; Novel isoforms of murine intercellular adhesion molecule-1 generated by alternative RNA splicing. J.Immunol 154: 6080-6093
- 36 Schmits R, Kündig TM, Baker DM, Shumaker G, Simard JJ L, Duncan G, Wakeham A, Shahinian A, van der Heiden A, Bachjmann MF, Ohashi PS, Mak TW, and Hickstein DD. 1996; LFA-1-deficient mice show normal CTL responses to virus but fail to reject immunogenic tumor. J.Exp.Med 183: 1415-1426
- 37 Shier P, Otulakowski G, Ngo K, Panakos J, Chourmouzis E, Christjansen L, Lau CY, and Fung-Leung WP. 1996; Impaired immune responses toward alloantigens and tumor cells but normal thymic selection in mice deficient in the (β2 integrin leukocyte function-associated antigen-1. J.Immunol 157: 5375-5386
- 38 Coxon A, Rieu P, Barkalow FJ, Askari S, von Andrian UH, Arnaout MA, and Mayadas TN. 1996; A novel role for the β2 integrin CD11b/CD18 in neutrophil apoptosis: a homeostatic mechanism in inflammation. Immunity 5: 653-666
- 39 Hodivala-Dilke KM, McHugh K, Raybum H, Teitelbaum S, and Hynes RO. 1997 Generation of mice null for β3 integrins, unpublished data.
- 40 Denis C, Rayburn H, Hynes RO, and Wagner DD. 1997. Generation of von Willebrand factor-deficient mice. Thromb.Haem. (in press).