Thrombosis and Haemostasis

Issue 02 · 2008

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Editorial Focus
249
Semple, John W.: Platelets play a direct role in sepsis-associated endothelial cell death

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Obituary
250
Augustin, Hellmut G.; Breier, Georg: Judah Folkman

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Theme Issue Editorial
251
Preissner, Klaus T.: From Molecules to Medicine: New Horizons in Vascular Biology and Thrombosis

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Theme Issue Article
253
Nurden, Paquita; Nurden, Alan T.: Congenital disorders associated with platelet dysfunctions

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264
Bergmeier, Wolfgang; Chauhan, Anil K.; Wagner, Denisa D.: Glycoprotein Ibα and von Willebrand factor in primary platelet adhesion and thrombus formation: Lessons from mutant mice

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271
Denis, Cécile V.; Christophe, Olivier D.; Oortwijn, Beatrijs D.; Lenting, Peter J.: Clearance of von Willebrand factor

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279
Barberis, Laura; Hirsch, Emilio: Targeting phosphoinositide 3-kinase γ to fight inflammation and more

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286
Kanse, Sandip M.; Parahuleva, Mariana; Muhl, Lars; Kemkes-Matthes, Bettina; Sedding, Daniel; Preissner, Klaus T.: Factor VII-activating protease (FSAP): Vascular functions and role in atherosclerosis

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290
Christiaens, Valerie; Scroyen, Ilse; Lijnen, H. Roger: Role of proteolysis in development of murine adipose tissue

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295
Hughes, Michael; Lip, Gregory Y. H.; on behalf of the Guideline Development Group for the NICE national clinical guideline for management of atrial fibrillation in primary and secondary care; on behalf of: Stroke and thromboembolism in atrial fibrillation: A systematic review of stroke risk factors, risk stratification schema and cost effectiveness data

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Review Article
305
Martorell, Lluis; Martínez-González, José; Rodríguez, Cristina; Gentile, Maurizio; Calvayrac, Olivier; Badimon, Lina: Thrombin and protease-activated receptors (PARs) in atherothrombosis

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Blood Coagulation, Fibrinolysis and Cellular Haemostasis
316
Inomo, Akifumi; Sugi, Toshitaka; Fujita, Yoshimi; Matsubayashi, Hidehiko; Izumi, Shun-ichiro; Mikami, Mikio: The antigenic binding sites of autoantibodies to factor XII in patients with recurrent pregnancy losses

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324
Zhang, Chuanling; Yu, Aiping; Yuan, Bin; Dong, Chunna; Yu, Hongyang; Wang, Lisheng; Wu, Chutse: Construction and functional evaluation of hirudin derivatives with low bleeding risk

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331
Rosenkranz, Andrea; Hiden, Michael; Leschnik, Bettina; Eva-Christine, Weiss; Schlembach, Dietmar; Lang, Uwe; Gallistl, Siegfried; Muntean, Wolfgang: Calibrated automated thrombin generation in normal uncomplicated pregnancy

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338
Adomaityte, Jurga; Farooq, Maria; Qayyum, Rehan: Effect of raloxifene therapy on venous thromboembolism in postmenopausal women: A meta-analysis

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343
Meier, Thomas R.; Myers, Daniel D.; Wrobleski, Shirley K.; Zajkowski, Paul J.; Hawley, Angela E.; Bedard, Patricia W.; Ballard, Nicole E.; Londy, Frank J.; Kaila, Neelu; Vlasuk, George P.; Schaub, Robert G.; Wakefield, Thomas W.: Prophylactic P-selectin inhibition with PSI-421 promotes resolution of venous thrombosis without anticoagulation

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352
Kinik, Sibel Tulgar; Özbek, Namik; Yuce, Muammer; Yazici, Ayse Canan; Verdi, Hasibe; Ataç, F. Belgin: PAI-1 gene 4G/5G polymorphism, cytokine levels and their relations with metabolic parameters in obese children

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Platelets and Blood Cells
357
Neubauer, Horst; Lask, Sebastian; Engelhardt, Andreas; Mügge, Andreas: How to optimise clopidogrel therapy? Reducing the low-response incidence by aggregometry-guided therapy modification

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Endothelium and Vascular Development
363
Kuckleburg, Christopher J.; Tiwari, Raksha; Czuprynski, Charles J.: Endothelial cell apoptosis induced by bacteria-activated platelets requires caspase-8 and -9 and generation of reactive oxygen species

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Cardiovascular Biology and Cell Signalling
373
Dorweiler, Bernhard; Torzewski, Michael; Dahm, Manfred; Kirkpatrick, Charles James; Lackner, Karl J.; Vahl, Christian-Friedrich: Subendothelial infiltration of neutrophil granulocytes and liberation of matrix-destabilizing enzymes in an experimental model of human neo-intima

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382
Orbe, Josune; Zudaire, Maite; Serrano, Rosario; Coma-Canella, Isabel; de Sizarrondo, Sara Martínez; Rodríguez, Jose A.; Páramo, Jose A.: Increased thrombin generation after acute versus chronic coronary disease as assessed by the thrombin generation test

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388
Carty, Cara L.; Cushman, Mary; Jones, Daniel; Lange, Leslie A.; Hindorff, Lucia A.; Rice, Kenneth; Jenny, Nancy S.; Durda, J. Peter; Walston, Jeremy; Carlson, Christopher S.; Nickerson, Debbie; Tracy, Russell P.; Reiner, Alex P.: Associations between common fibrinogen gene polymorphisms and cardiovascular disease in older adults

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Cellular Proteolysis and Oncology
396
Stender, Mogens Tornby; Frøkjær, Jens Brøndum; Nielsen, Tina Sandie Hagedorn; Larsen, Torben Bjerregaard; Lundbye-Christensen, Søren; Elbrønd, Henrik; Thorlacius-Ussing, Ole: Combined use of clinical pre-test probability and D-dimer test in the diagnosis of preoperative deep venous thrombosis in colorectal cancer patients

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Animal Models
401
Souri, Masayoshi; Koseki-Kuno, Shiori; Takeda, Naoki; Yamakawa, Mitsunori; Takeishi, Yasuchika; Degen, Jay L.; Ichinose, Akitada: Male-specific cardiac pathologies in mice lacking either the A or B subunit of factor XIII

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New Technologies, Diagnostic Tools and Drugs
409
Jakubowski, Joseph A.; Payne, Christopher D.; Li, Ying G.; Brandt, John T.; Small, David S.; Farid, Nagy A.; Salazar, Daniel E.; Winters, Kenneth J.: The use of the VerifyNow P2Y12 point-of-care device to monitor platelet function across a range of P2Y12 inhibition levels following prasugrel and clopidogrel administration

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416
Zürcher, Manuel; Sulzer, Irmela; Barizzi, Gabriela; Lämmle, Bernhard; Alberio, Lorenzo: Stability of coagulation assays performed in plasma from citrated whole blood transported at ambient temperature

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Supplementary Material

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427
Raivio, Peter; Kuitunen, Anne; Petäjä, Jari; Ilveskero, Sorella; Lassila, Riitta: Monitoring high-dose heparinization during cardiopulmonary bypass – A comparison between prothrombinase-induced clotting time (PiCT) and two chromogenic anti-factor Xa activity assays

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435
Tymvios, Charalambos; Jones, Sarah; Moore, Christopher; Pitchford, Simon C.; Page, Clive P.; Emerson, Michael: Real-time measurement of non-lethal platelet thromboembolic responses in the anaesthetized mouse

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Case Report
441
De Paulis, Stefano; Rossi, Elena; Zamparelli, Roberto; Scapigliati, Andrea; Corrado, Michele; De Stefano, Valerio: Early postoperative obstructive prosthetic mitral valve thrombosis in a patient double heterozygous for factor V Leiden and prothrombin G20210A mutation

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443
Barba, Pere; Santamaría, Amparo; Tirado, Isabel; Martí, Edelmira; Fontcuberta, Jordi: Antithrombin Cambridge II mutation as a risk factor to develop cerebral venous thrombosis

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445
Jeanneret, Christina; Reutlinger, Christian; Hirsch, Hans H.; Cathomas, Gieri; Rothen, Madeleine; Martius, Ferdinand; Biedermann, Barbara C.: Multifocal thrombophlebitis and deep vein thrombosis in primary cytomegalovirus infection – A histopathological analysis

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Letters to the Editor
448
Morel, Olivier; Bernhard, Nicolas; Desprez, Dominique; Grunebaum, Lelia; Freyssinet, Jean-Marie; Toti, Florence; Bareiss, Pierre: Residual prothrombotic status in low responder patients to clopidogrel identified by Vasodilator-Stimulated Phosphoprotein Phosphorylation (VASP) analysis?

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451
Marchi, Rita; Carvajal, Zoila; Weisel, John W.: Comparison of the effect of different homocysteine concentrations on clot formation using human plasma and purified fibrinogen

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453
Pecheniuk, Natalie M.; Elias, Darlene J.; Xu, Xiao; Griffin, John H.: Failure to validate association of gene polymorphisms in EPCR, PAR-1, FSAP and protein S Tokushima with venous thromboembolism among Californians of European ancestry

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