Synthesis 2014; 46(03): 343-347
DOI: 10.1055/s-0033-1338568
paper
© Georg Thieme Verlag Stuttgart · New York

NIS-Mediated Oxidative Lactonization of 2-Arylbenzoic Acids for the Synthesis­ of Dibenzopyranones under Metal-Free Conditions

Peng Gao
School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. of China   Fax: +86(25)84317078   Email: ywei@mail.njust.edu.cn
,
Yunyang Wei*
School of Chemical Engineering, Nanjing University of Science and Technology, Nanjing 210094, P. R. of China   Fax: +86(25)84317078   Email: ywei@mail.njust.edu.cn
› Author Affiliations
Further Information

Publication History

Received: 10 October 2013

Accepted after revision: 11 November 2013

Publication Date:
02 December 2013 (online)


Abstract

A series of dibenzopyranones were synthesized from 2-arylbenzoic acids by a radical oxidative cyclization procedure mediated by N-iodosuccinimide (NIS). The methodology is distinguished by its practicality in terms of its wide substrate scope, good functional group tolerance, and mild reaction conditions without the use of transition metals.

Supporting Information

 
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