DOI: 10.1055/s-00000131

Synfacts

Ausgabe 03 · Volume 17 · März 2021 DOI: 10.1055/s-011-50344

Synform

  • A34

    SYNFORM ISSUE 2021/03

    • Synthesis of Natural Products and Potential Drugs

  • z0235

    All PDFs of this category

  • 0235

    Synthesis of a BACE1 Inhibitor

  • 0236

    Synthesis of Molnupiravir from Uridine

  • 0237

    Total Synthesis of (–)-Berkelic Acid

  • 0238

    Synthesis of Pyrido[2,3-b]indoles Targeting DNA Gyrase and Topisomerase IV

  • 0239

    Collective Total Synthesis of Casbane Diterpenes: One Strategy, Multiple Targets

  • 0240

    Synthesis of Pamiparib

  • 0241

    Synthesis of (±)-Rubiginosins A, D, and G

  • 0242

    Synthesis of CC-90011

  • 0243

    Synthesis of AZD9833

  • 0244

    Synthesis of Daridorexant

  • 0245

    Synthesis of (±)-Lyconesidine B

  • 0246

    Synthesis of BMS-986144

  • 0247

    PIM Kinase Inhibitor

  • 0248

    Total Synthesis of (+)-Rumphellclovane E

  • 0249

    Synthesis of Vixotrigine

  • 0250

    Synthesis of Chitinase Inhibitor OATD-01

  • 0251

    Total Synthesis of (±)-Strychnine

  • 0252

    Total Synthesis of (–)-Cepharamine

  • 0253

    Synthesis of Brensocatib (AZD7986)

    • Synthesis of Heterocycles

  • z0255

    All PDFs of this category

  • 0255

    Thermally Promoted Synthesis of β-Lactam Derivatives

  • 0256

    Rhodium-Catalyzed Synthesis of 1H‑Indole-2,3-dicarboxylates from Arylhydrazines and Maleates

  • 0257

    Enzymatic Syntheses of Tryptophan Analogues and Incorporation in Biocatalytic Cascades

  • 0258

    Increasing the 3D-Character of Heterocyclic Systems through Hydrogenation

  • 0259

    Diastereoselective Atom-Economical Synthesis of Dihydropyrans

  • 0260

    Rhodium-Catalyzed Synthesis of Chiral Hydrophenanthridinones

  • 0261

    Rhodium-Catalyzed Synthesis of Chiral 3,4-Fused Tricyclic Indoles

  • 0262

    Rhodium-Catalyzed Synthesis of 1,3-Benzodiazepines

  • 0263

    One-Pot Condensation to Tricyclic Azepines

  • 0264

    Synthesis of 1,2,4-Triazoles by Annulation of Nitriles with Hydrazines

  • 0265

    Cascade Reaction for the Enantioselective Synthesis of Pyrrolizidones

  • 0266

    Rhodium-Catalyzed C–H Activation To Form Macrolactams

    • Synthesis of Materials and Unnatural Products

  • z0267

    All PDFs of this category

  • 0267

    How Many Sulfurs are Enough? A Tuning Study on [1,3]-Dioxolo[4.5-f]benzodioxole (DBD) Dyes

  • 0268

    Mechanochemical Synthesis of Pilar[5]quinone-Derived Porous Polymers

  • 0269

    NHC-Catalyzed Benzoin Condensation for Access to New Cyclotetrabenzoins

  • 0270

    Light-Mediated Polymerization Switch

  • 0271

    Making a Strong Binder Weak

  • 0272

    Reductive Thiolation of Organic Halides via Nickel-Catalyzed Cross-Coupling

  • 0273

    Facile Metal-Free Synthesis of Polyaryl-Substituted Pyrroles

  • 0274

    Sulfur Alchemy: Exotic Aromatics from Thiophenes

  • 0275

    Heavy Indoles: Synthesis of Benzo[b]arsoles

  • 0276

    EE-ZZ Access to Azobenzene-Based Macrocycles

  • 0277

    Synthesis of Imide-Selenophene Based Polymers

  • 0278

    A Feast of πs

    • Metals in Synthesis

  • z0279

    All PDFs of this category

  • 0279

    Regioselective Iron-Catalyzed 1,2-Diamination of Unactivated Alkenes

  • 0280

    Triazenyl Alkynes for the Synthesis of β-Amino Amides

  • 0281

    Ruthenium-Catalyzed Hydrogenation of Thioesters

  • 0282

    Aniline Oxidation for Synthesis of Azo- and Azoxybenzenes

  • 0283

    Copper-Catalyzed Synthesis of β-Boryl Amides from Alkenes

  • 0284

    Chemoselective Synthesis of Vinylcyclobutanes via Rh-Catalyzed Ring Opening of Vinylcyclopropanes

  • 0285

    Cobalt-Catalyzed Enantioselective Hydroalkylation of Cyclopropenes with Cyclopropanols

  • 0286

    Palladium-Catalyzed Acylation of Indolines using 1,2-Dicarbonyls

  • 0287

    Ruthenium-Catalyzed Electrochemical Synthesis of Isoquinolines

  • 0288

    Copper-Catalyzed Formation of Aryl Ethers

  • 0289

    Aziridination of Fluorinated Olefins

  • 0290

    Acridinium Photocatalysts for C–O Bond Cleavage of Diaryl Ethers

  • 0291

    Redox-Neutral Manganese-Catalyzed Silylation of Alkenes

  • 0292

    Enantioselective Copper-Catalyzed Allylation of Prochiral Geminal Diborylalkanes

  • 0293

    Palladium-Catalyzed C(sp3)–H Allylation of 4-Alkylpyridines

  • 0294

    Preparation of Arylated gem-Difluoroalkenes

  • 0295

    Light-Mediated Radical α-Arylation of Amides

  • 0296

    Enantioselective Rh-Catalyzed Asymmetric Allylation/Tschitschibabin Reaction Sequence

  • 0297

    Iridium-Catalyzed Enantioselective β-C(sp3)–H Borylation of Amides

  • 0298

    Difluoromethylation of Enol Acetates

  • 0299

    Nickel-Catalyzed Carboalkenylation of 1,3-Dienes

  • 0300

    Copper-Catalyzed Enantioselective Aminoalkynylation of Styrenes

  • 0301

    Photoredox- and Nickel-Catalyzed Phosphonylation of Aryl Halides

  • 0302

    Enantioselective Preparation of Chiral 2-Substituted Propanamides

  • 0303

    Convergent Synthesis of Complex Alkyl Boronates

  • 0304

    Nickel-Catalyzed Dynamic Kinetic Deoxyarylation of Benzylic Alcohols by Cross-Coupling

  • 0305

    1,2-Dialkylation of Substituted Acrylates Enabled by Photoredox Chemistry

  • 0306

    Double Functionalization of Alkenes via C–H Activation

  • 0307

    Larock Indole Synthesis

    • Polymer-Supported Synthesis

  • z0309

    All PDFs of this category

  • 0309

    Photoredox C–O Cross Coupling of Aryl Halides and Alcohols on Nickel-Coordinated Carbon Nitride

  • 0310

    Carboxylative Cyclization of Propargylic Alcohols on a Vanadium–Copper Metal–Organic Framework

  • 0311

    Photocatalytic Heck Reaction on a Graphene Oxide-Immobilized Bis(terpyridine)ruthenium(II) Complex

  • 0312

    Cadmium Sulfide Quantum Dot-Promoted C–C Coupling of Benzylic Alcohols

  • 0313

    Zirconium–Palladium Intermetallic Nanocatalyst for Suzuki–Miyaura Cross-Coupling

  • 0314

    Zinc Mediated Defluorinative Alkylation of α-(Trifluoromethyl)styrenes

  • 0315

    Suzuki–Miyaura Coupling Reactions Catalyzed by Palladium Supported on Silk Fibroin

  • 0316

    Hydrogenation of Arenes on a Polymer-Stabilized Palladium–Ruthenium Bimetallic Composite

  • 0317

    Quantum Dot-Photocatalyzed Stereoselective Oxidative Dimerization of α-Aryl Ketonitriles

  • 0318

    C–C and C–N Cross-Coupling Catalyzed by Polymer-Supported Ni/Pd on Fe3O4@SiO2 Nanoparticles

    • Organo- and Biocatalysis

  • z0319

    All PDFs of this category

  • 0319

    Triplet-Sensitized General Oxyimination of Olefins

  • 0320

    Phosphoric Acid Permits Asymmetric Synthesis of Hitherto Underinvestigated Chiral Tetraarylmethanes

  • 0321

    Immobilized Chiral Phosphoric Acid Catalysts for Continuous-Flow Desymmetrization of Oxetanes

  • 0322

    Enzyme-Controlled Highly Selective N-Alkylation of Pyrazoles with Simple Haloalkanes

  • 0323

    Biocatalytic Synthesis of Trisubstituted Cyclopropanes Containing Fluoromethylated Groups

  • 0324

    Organophotoredox Catalysis Permits Site-Selective Bioconjugation of Methionine Residues

  • 0325

    Visible Light-mediated Enantioselective Radical Addition to α,β-Unsaturated Aldehydes

  • 0326

    Chemical Synthesis Reveals the Odorous Principle of Vetiver Oil

  • 0327

    Asymmetric Intramolecular Hydroarylations of Nonactivated Olefins with Indoles

  • 0328

    Efficient Conversion of CO2 into Cyclic Carbonates with Durable and Recyclable Organoboron Catalysts

  • 0329

    Thiophosphorylation of Nucleosides Reveals New Mechanism in Cinchona Alkaloid-Catalysis

    • Chemistry in Medicine and Biology

  • z0331

    All PDFs of this category

  • 0331

    Lysine-Selective Oxidative Addition Complexes for the Conjugation of Proteins, Antibodies, and Peptides

  • 0332

    Selective PI3Kγ Inhibitors for in vivo Studies

  • 0333

    Inhibition of Mitochondrial Transcription

  • 0334

    A Brain-Penetrant mTOR Kinase Inhibitor for the Treatment of Neurological Disorders

  • 0335

    Tabernanthalog, an Ibogaine Analogue for Treatment of Addiction and Depression

  • 0336

    Covalent Inhibitors and Fluorescent Probes for Investigation of SARS-CoV-2 Mpro in Patient Samples

  • 0337

    PET Imaging of Alzheimer’s Disease With a 64Cu Multivalent Bifunctional Chelator

  • 0338

    Pamiparib – A Promising PARP Inhibitor

  • 0339

    Styrylbenzothiazoles – A New Class of Photoswitches

  • 0340

    A Novel and Highly Selective FAK Inhibitor

  • 0341

    Antibiotics in a Trojan Horse

  • 0342

    Ratiometric Fluorescent Sensing of Intracellular Potassium

  • 0343

    The First Synthesis of Morphine

    • Peptide Chemistry

  • z0345

    All PDFs of this category

  • 0345

    Fluorine-Containing Azaheterocyclic β-Amino Acids

  • 0346

    Brønsted-Acid-Catalyzed Enantioselective Aza-Friedel–Crafts Reaction

  • 0347

    Rhodium-Catalyzed Formation of Disulfide Bonds in Water

  • 0348

    Synthesis of Cyclic Peptides by Cooperative Stapling of Native Peptides at Lysine and Tyrosine or Arginine

  • 0349

    Synthesis of Tetrasubstituted α-Amino Acids by an Ireland–Claisen Rearrangement

  • 0350

    Silver-Promoted Synthesis of Cyclic Peptides by Ring Expansion

  • 0351

    Chlorophyll-Catalyzed 1,2-Acyl Migration of Enaminones To Give Quaternary α-Amino Esters

  • 0352

    Boron-Containing Aza-Amino Acids

  • 0353

    Nickel-Catalyzed Hydroamination of Alkenes

  • 0354

    Radical Substitution Reaction for the Synthesis of Nonnatural Amino Acid and Peptides

  • 0355

    Late-Stage Site-Selective Rhodium-Catalyzed C(7)-Amidation of Tryptophan Residues

  • 0356

    Peptides Synthesis by Using Nitrophenyl Esters

    • Flow Chemistry

  • z0357

    All PDFs of this category

  • 0357

    Synthesis of Hydroxy Esters under Flow Conditions

  • 0358

    Rhodium-Catalyzed C–H Activation of Benzylamines for Olefin Hydroarylation

  • 0359

    Continuous-Flow Procedure for the Synthesis of Benzotriazoles via [3+2] Cycloaddition

  • 0360

    Asymmetric Synthesis of Chloramphenicol and Related Amphenicol Antibiotics

    • Erratum

  • 0361

    Cobalt-Catalyzed Synthesis of Pyrroles from Nitroarenes