Dong J,
Yuan X.-A,
Yan Z,
Mu L,
Ma J,
Zhu C,
Xie J.
*
Nanjing University, P. R. of China
Manganese-Catalysed Divergent Silylation of Alkenes.
Nat. Chem. 2021;
13: 182-190
DOI:
10.1038/s41557-020-00589-8
Key words
manganese catalysis - hydrosilylation - dehydrosilylation - redox-neutral reaction - manganese radicals
Significance
Xie and co-workers report a manganese-catalyzed dehydrosilylation and hydrosilylation of alkenes. They have shown that the reaction is easily scalable and affords the silylated product in good yields. The reaction proceeds equally well with both aliphatic and aromatic alkene starting materials.
Comment
Notably, the reaction is highly selective for the linear silylated product, stemming from the anti-Markovnikov addition of the silyl radical to the alkene. Additionally, under the specific conditions, either the dehydrosilylation or hydrosilylation product can be accessed with excellent selectivity.
