DOI: 10.1055/s-00000131

Synfacts

Issue 01 · Volume 15 · January 2019 DOI: 10.1055/s-008-42067

Editorial

III
Editorial

Synform

A1
Zanda, Matteo: SYNFORM ISSUE 2019/01

Synthesis of Natural Products and Potential Drugs

z0001
All PDFs of this category
0001
Synthesis of Isopalhinine A and Palhinine D
0002
Enantioselective Syntheses of Divergolides E and H
0003
Synthesis of Beclabuvir
0004
Synthesis of an Atropisomer of Schiglautone A
0005
Synthesis of Efavirenz via Asymmetric Alkynylation
0006
Synthesis of (±)-Repraesentin F
0007
Synthesis of Prostaglandins F2α and E2
0008
Synthesis of Flibanserin
0009
Total Synthesis of (+)–Chaetoglobin A
0010
Synthesis of BMS-214662
0011
Synthesis of Cefiderocol
0012
Synthesis of Quetiapine via Cobalt-Catalyzed C–H Thiolation
0013
Total Synthesis of Brasilicardins A–D

Synthesis of Heterocycles

z0015
All PDFs of this category
0015
Synthesis of N-Doped Polycyclic Aromatic Hydrocarbons
0016
Organocatalytic Approach to cis-Octahydroacridines
0017
Synthesis of Perfluoroalkylated Spirobarbiturates
0018
Iridium-Catalyzed C–H Alkenylations: Synthesis of 3-Alkylisobenzofuran-1(3H)-ones
0019
Reaction of Cyclobutanones with Allenylsilanes to form Oxabicyclo[3.2.1]octanes
0020
Photocatalytic Synthesis of 8- to 11-Membered Lactams by C–C Bond Cleavage
0021
Multicomponent Reaction Approach to Aza Analogues of Tropane Alkaloids
0022
Functionalized 2H-Isoindoles by Rhodium-Catalyzed C–H Activation
0023
Metallophotoredox-Catalyzed C–H Arylation of C(sp3)–H Bonds
0024
Ionic-Liquid-Mediated Syntheses of Fused Pyrimidines and Quinazolines
0025
Carbocyclization through an Interrupted Carbonyl–Olefin Metathesis
0026
Synthesis of Pyrrolopyrazinones from N-Substituted 2-Cyanopyrroles
0027
Synthesis of 2‑Aminoquinolines from N‑Acyl‑o‑alkynylanilines
0028
Borane-Catalyzed Synthesis of Azasilaheterocycles
0029
One-Pot Synthesis of Isoquinolinones by Rhodium-Catalyzed C–H Activation

Synthesis of Materials and Unnatural Products

z0031
All PDFs of this category
0031
Catalytic, Oxidative Alkene Arylation for Polycyclic Aromatic Hydrocarbons
0032
Synthesis of Corannulenes Revisited
0033
Endo, Exo, and What?
0034
Sequence-Regulated Synthetic Polymers are Just a Few Clicks Away
0035
Some Like It Branched: Fluorous Tags for Enhanced Solubility and Biocompatibility
0036
Construction of Axial Chirality by Intramolecular Consecutive Dehydro-Diels–Alder Reaction
0037
One-Pot, Multicomponent Synthesis of Helical Quinolines
0038
Not so Boring Boron: C-Halogenated 9,10-Diboraantharcenes
0039
Breaking Up Kekulene, Resulting in π-Expanded Helicene
0040
Modular Route to N-Substituted peri-Xanthenoxanthene Mono- and Diimides
0041
Ring-Opening Metathesis Oligomerization to Close Macromolecular Cages
0042
Synthesis of a Photoisomerizable Bis-cyclooctyne Cross-Linker

Metals in Synthesis

z0043
All PDFs of this category
0043
C–C Bond Formation Using Nickel-Photoredox Catalysis
0044
Palladium Catalyzed Enantioselective α-Allylation of Aryl Acetic Acids
0045
Enantioselective Palladium-Catalyzed Dearomative Heck Reaction
0046
Photochemical Gold-Catalyzed Arylations
0047
Biaryl Ligands for C–N Coupling
0048
Palladium-Catalyzed Domino Ring-Opening/Spirocyclization Process
0049
The First Csp2–Csp2 Cross-Coupling Using Organozinc Reagents
0050
Rhodium-Catalyzed Allylic C–H Etherification
0051
Iridium-Catalyzed Alkylations of Aromatic Aldehydes
0052
para-Selective Difluoromethylation of Aromatic Ketones
0053
Rhodium-Catalyzed Kinetic Resolution of Homoallylic Secondary Alcohols
0054
Copper-Catalyzed Radical Cross-Coupling Multicomponent Reaction
0055
Rhodium(III) C–H Activation Combined with N- and C-Annulations
0056
Enantioselective Addition of Chiral Metal Enolates to ortho-Quinone Methides
0057
Simple and Environmentally Friendly Synthesis of Amides
0058
Enantioselective Alkylation of Imines via Copper-Catalyzed Asymmetric Photoredox
0059
Nickel-Catalyzed Suzuki–Miyaura Reaction with no Exogenous Base
0060
Copper-Catalyzed Dichloromethylation and Subsequent Azide Trap
0061
A Nickel-Catalyzed Photoredox Tsuji–Trost Reaction
0062
Nickel-Catalyzed Alkylation using Anhydrides
0063
Iodine Atom Transfer Catalysis via Ketyl Radicals
0064
Iron-Catalyzed Carbenoid Transfer Heterocycle Synthesis
0065
Iridium-Photocatalyzed Synthesis of Complex Alkylamines
0066
Reductive Coupling of Tertiary Alkyl Halides and Electron-Rich Aryl Iodides
0067
Enantioselective Intramolecular Dearomative Allylic Alkylation
0068
Suzuki–Miyaura Cross-Coupling of Dimethyl Aryl Amines
0069
Palladium-Catalyzed Allylations Using Hydrazones as Carbanion Surrogates
0070
Ruthenium-Catalyzed Photoredox Alkylamination

Polymer-Supported Synthesis

z0071
All PDFs of this category
0071
Desilylative or Decarboxylative Photoadditions with Graphitic Carbon Nitride
0072
N-Formylation of Amines Catalyzed by Self-Supported N-Heterocyclic Carbene–Iridium
0073
Reductive Amination and Hydroaminomethylation with a Bifunctional Catalyst
0074
Synthesis of Pyrroles from 3,6-Dihydro-2H-1,2-oxazines on Cu/C
0075
Hydrogenation of Pyridines on Titania-Supported Cobalt Nanoparticles
0076
Graphene Oxide Catalyzed Synthesis of Spiropyrrolizines
0077
Photocatalytic Aerobic Oxidation of Alkylaromatics on Pt/Bi2MoO6
0078
Reduction of Nitroarenes to Azoarenes on Cage-Encapsulated Gold Nanoparticles
0079
Molybdenum Sulfide-Mediated C–H Arylation of Heteroarenes with Arenediazonium Salts
0080
Synthesis of Benzoxanthenes and Pyrroles on a Supported Lewis Acidic Ionic Liquid
0081
Asymmetric Fluorination on a Polystyrene-Supported Copper Complex
0082
Reduction of Nitroarenes on N-Doped Porous Carbon-Supported Cobalt

Organo- and Biocatalysis

z0083
All PDFs of this category
0083
Chiral Lewis Base Catalyzed Aldol Reaction of Unprotected Carboxylic Acids
0084
Stereodynamic Redox-Interconversion Network of Hybrid Dihydrobenzofurans
0085
The Dawn of Directed Evolution
0086
Bienzymatic Oxidative Lactamization of Aliphatic Amino Alcohols
0087
Carbon–Fluorine Bond Cleavage by an Engineered Enzyme
0088
Reductive C–N Cross-Coupling of Nitroarenes by PIII/PV=O Catalysis
0089
Cinchona-Amine-Catalyzed Stepwise [6+4] Cycloadditions
0090
Catalytic Diels–Alder Reaction of α,β-Unsaturated Methyl Esters
0091
Organocatalytic Synthesis of γ,γ-Disubstituted Butenolides
0092
From CO2 to Cyclic Carbonates: Organocatalysts Do It under Mild Conditions
0093
Improved Efficiency with New Cinchona-Based Catalysts in Umpolung Reactions

Peptide Chemistry

z0095
All PDFs of this category
0095
Stereoselective Synthesis of α-Aryl Amino Acids
0096
Peptide Macrocyclization by Palladium-Catalyzed δ-C(sp2)–H Olefination
0097
Synthesis of Backbone-Engineered HIV Protease by Selective Chemical Ligation
0098
Direct Peptide Synthesis via N-Acyl Imidazolium Intermediates
0099
2,4-Bis(trifluoromethyl)phenylboronic Acid Catalyzed Amidation
0100
Modified Yamaguchi Reagent Mediated Coupling Reactions
0101
Tris(2,2,2-Trifluoroethyl) Borate Catalyzed, Protecting-Group-Free Amidation
0102
Native Chemical Ligation by Flow Chemistry

Flow Chemistry

z0103
All PDFs of this category
0103
Synthesis of Substituted Allylic Alcohols in Continuous Flow under UV-Light
0104
A Catalytic Hydrogenation of Arenes: Batch versus Flow
0105
Versatile Flow-Based Automatic Reaction Optimization Platform
0106
Continuous Flow Synthesis of Eflornithine
0107
Continuous-Flow Synthesis of Amines and Hydroxylamines
0108
Chloroacetate Claisen Reactions in Continuous Flow