Arzneimittelforschung

Issue 02 · February 2006

Issue
CNS-active Drugs · Hypnotics · Psychotropics · Sedatives
59
Almeida, Susana; Filipe, Augusto; Almeida, Ana; Antonijoan, Rosa; García-Gea, Consuelo; Gich, Ignasi; Barbanoj, Manuel; Caturla, Maria Cruz: Comparative Study on the Bioequivalence of Two Different Gabapentin Formulations

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Lipid Reducers
64
Bradamante, Vlasta; Krnić, Žarka; Zrinski, Renata; Konjevoda, Paško; Reiner, Željko: Changes in Butyrylcholinesterase Activity and Serum Lipids after Oxprenolol and Glibenclamide Treatments in Non-diabetic Rats

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Lipidsenker
70
Almeida, Susana; Filipe, Augusto; Almeida, Ana; Gich, Ignasi; Antonijoan, Rosa; Puntes, Montserrat; Barbanoj, Manuel; Caturla, Maria Cruz: Comparative Study on the Bioequivalence of Two Formulations of Pravastatin

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Antiallergic Drugs · Antiasthmatics · Antitussives · Bronchodilators · Bronchosecretogogues · Mucolytics
76
Zimmer, Guido; Bernhörster, Markus; Pilz, Patrizius; Schuchmann-Fix, Jutta; Hüggelmeier, Rolf; Blüm, Nicole; Libertus, Herman: Mononuclear Cell Membranes: Stabilization by Reproterol and Cromoglycate, Destabilization by Fenoterol and Salbutamol

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Antiosteoporotic Drugs · Chondroprotective Drugs
84
Almeida, Susana; Almeida, Ana; Filipe, Augusto; Penedo, Clarisse; Rocha, Alexandre; Lainesse, Audrey; Vallée, François: In vitro Disintegration and Dissolution and in vivo Bioequivalence of Two Alendronate Once-weekly Formulations

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Antioxidants
90
Kurcer, Zehra; Iraz, Mustafa; Kelesyilmaz, Nedim; Kilic, Nermin; Olmez, Ercument: Beneficial Effects of Melatonin on Diaphragmatic Contractility and Fatigability in Escherichia coli Endotoxemic Rats

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Antibiotics · Antiviral Drugs · Chemotherapeutics · Cytostatics
96
Bijev, Atanas: Synthesis and Preliminary Screening of Carbohydrazides and Hydrazones of Pyrrole Derivatives as Potential Tuberculostatics

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104
Lotfy, Abeya A. M.; Ghanem, Lobna Y.; Shennawy, Amal M.; Gomaa, Nadia A.; El Said, Hamda H.: Assessment of the Toxicity of Artemisia inculta Extract on the Bone Marrow of Mice Infected with Schistosomiasis

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Special Themes
108
Liedtke, Rainer K.: Pharmacological Concept for Topical Synergistic Analgesia of Peripheral Neuromuscular Pain

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Book Reviews
115
Book Reviews

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Preface
117
Unmet Challenges in HIV Therapy and Potential of Stampidine

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Stampidine
121
Uckun, Fatih M.: Stampidine as a Novel Nucleoside Reverse Transcriptase Inhibitor with Potent Anti-HIV Activity

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136
DuMez, Darin; Venkatachalam, Taracad K.; Uckun, Fatih M.: Large-Scale Synthesis and Formulation of GMP-Grade Stampidine, a New Anti-HIV Agent

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152
Venkatachalam, Taracad K.; Qazi, Sanjive; Uckun, Fatih M.: Synthesis, Separation and Anti-HIV Activity of Distereoisomers of N-[p-(4-Bromophenyl)-2',3'-didehydro-3'-deoxy-5'-thymidylyl]-L-alanine Methyl Ester (Stampidine)

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159
D'Cruz, Osmond J.; Erbeck, Douglas; Uckun, Fatih M.: Developmental Safety Profile of the Anti-HIV Agent Stampidine in Rabbits

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167
Venkatachalam, Taracad K.; Qazi, Sanjive; Uckun, Fatih M.: Site-Specific Enzymatic Activation of the Anti-HIV Agent Stampidine

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176
Uckun, Fatih M.; Waurzyniak, Barbara; Tibbles, Heather; Venkatachalam, Taracad K.; Erbeck, Doug: In vivo Pharmacokinetics and Toxicity Profile of the Anti-HIV Agent Stampidine in Dogs and Feline Immunodeficiency Virus-infected Cats

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193
Uckun, Fatih M.; Venkatachalam, Taracad K.; Qazi, Sanjive: Potency of Stampidine Against Multi-Nucleoside Reverse Transcriptase Inhibitor Resistant Human Immunodeficiency Viruses

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