DOI: 10.1055/s-00000175

Arzneimittelforschung

Ausgabe 02 · Volume 56 · Februar 2006 DOI: 10.1055/s-002-22597

CNS-active Drugs · Hypnotics · Psychotropics · Sedatives

59
Almeida, Susana; Filipe, Augusto; Almeida, Ana; Antonijoan, Rosa; García-Gea, Consuelo; Gich, Ignasi; Barbanoj, Manuel; Caturla, Maria Cruz: Comparative Study on the Bioequivalence of Two Different Gabapentin Formulations

Lipid Reducers

64
Bradamante, Vlasta; Krnić, Žarka; Zrinski, Renata; Konjevoda, Paško; Reiner, Željko: Changes in Butyrylcholinesterase Activity and Serum Lipids after Oxprenolol and Glibenclamide Treatments in Non-diabetic Rats

Lipidsenker

70
Almeida, Susana; Filipe, Augusto; Almeida, Ana; Gich, Ignasi; Antonijoan, Rosa; Puntes, Montserrat; Barbanoj, Manuel; Caturla, Maria Cruz: Comparative Study on the Bioequivalence of Two Formulations of Pravastatin

Antiallergic Drugs · Antiasthmatics · Antitussives · Bronchodilators · Bronchosecretogogues · Mucolytics

76
Zimmer, Guido; Bernhörster, Markus; Pilz, Patrizius; Schuchmann-Fix, Jutta; Hüggelmeier, Rolf; Blüm, Nicole; Libertus, Herman: Mononuclear Cell Membranes: Stabilization by Reproterol and Cromoglycate, Destabilization by Fenoterol and Salbutamol

Antiosteoporotic Drugs · Chondroprotective Drugs

84
Almeida, Susana; Almeida, Ana; Filipe, Augusto; Penedo, Clarisse; Rocha, Alexandre; Lainesse, Audrey; Vallée, François: In vitro Disintegration and Dissolution and in vivo Bioequivalence of Two Alendronate Once-weekly Formulations

Antioxidants

90
Kurcer, Zehra; Iraz, Mustafa; Kelesyilmaz, Nedim; Kilic, Nermin; Olmez, Ercument: Beneficial Effects of Melatonin on Diaphragmatic Contractility and Fatigability in Escherichia coli Endotoxemic Rats

Antibiotics · Antiviral Drugs · Chemotherapeutics · Cytostatics

96
Bijev, Atanas: Synthesis and Preliminary Screening of Carbohydrazides and Hydrazones of Pyrrole Derivatives as Potential Tuberculostatics
104
Lotfy, Abeya A. M.; Ghanem, Lobna Y.; Shennawy, Amal M.; Gomaa, Nadia A.; El Said, Hamda H.: Assessment of the Toxicity of Artemisia inculta Extract on the Bone Marrow of Mice Infected with Schistosomiasis

Special Themes

108
Liedtke, Rainer K.: Pharmacological Concept for Topical Synergistic Analgesia of Peripheral Neuromuscular Pain

Book Reviews

115
Book Reviews

Preface

117
Unmet Challenges in HIV Therapy and Potential of Stampidine

Stampidine

121
Uckun, Fatih M.: Stampidine as a Novel Nucleoside Reverse Transcriptase Inhibitor with Potent Anti-HIV Activity
136
DuMez, Darin; Venkatachalam, Taracad K.; Uckun, Fatih M.: Large-Scale Synthesis and Formulation of GMP-Grade Stampidine, a New Anti-HIV Agent
152
Venkatachalam, Taracad K.; Qazi, Sanjive; Uckun, Fatih M.: Synthesis, Separation and Anti-HIV Activity of Distereoisomers of N-[p-(4-Bromophenyl)-2',3'-didehydro-3'-deoxy-5'-thymidylyl]-L-alanine Methyl Ester (Stampidine)
159
D'Cruz, Osmond J.; Erbeck, Douglas; Uckun, Fatih M.: Developmental Safety Profile of the Anti-HIV Agent Stampidine in Rabbits
167
Venkatachalam, Taracad K.; Qazi, Sanjive; Uckun, Fatih M.: Site-Specific Enzymatic Activation of the Anti-HIV Agent Stampidine
176
Uckun, Fatih M.; Waurzyniak, Barbara; Tibbles, Heather; Venkatachalam, Taracad K.; Erbeck, Doug: In vivo Pharmacokinetics and Toxicity Profile of the Anti-HIV Agent Stampidine in Dogs and Feline Immunodeficiency Virus-infected Cats
193
Uckun, Fatih M.; Venkatachalam, Taracad K.; Qazi, Sanjive: Potency of Stampidine Against Multi-Nucleoside Reverse Transcriptase Inhibitor Resistant Human Immunodeficiency Viruses