Organosilanes in Copper-Mediated Conjugate Reductions and Reductive Aldol Reactions

Abstract

Organosilanes have been used to synthesize and regenerate copper hydrides, and have been employed as stoichiometric reductants in the copper-catalyzed reductions of a variety of activated olefins. Reductive aldol condensations and cyclizations using organosilanes and transition metal catalysts, including copper hydrides, have also been achieved.

Key words

organosilanes - copper conjugate reductions - aldol reactions

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