Abstract
Electrochemistry has recently gained increased attention as a versatile strategy for
achieving challenging transformations at the forefront of synthetic organic chemistry.
However, most electrochemical transformations only employ one electrode (anodic oxidation
or cathodic reduction) to afford the desired products, while the chemistry that occurs
at the counter electrode yields stoichiometric waste. In contrast, paired electrochemical
reactions can synchronously utilize the anodic and cathodic reactions to deliver the
desired product, thus improving the atom economy and energy efficiency of the electrolytic
process. This review gives an overview of recent advances in nickel-catalyzed paired
electrochemical cross-coupling reactions of aryl/alkenyl halides with different nucleophiles.
1 Introduction
2 Nickel-Catalyzed Cross-Coupling Reactions
2.1 C–C Bond Formation
2.2 C–N Bond Formation
2.3 C–S/O Bond Formation
2.4 C–P Bond Formation
3 Conclusion
Key words
electrochemistry - paired electrolysis - nickel catalysis - cross-coupling - redox
neutral reactions