Dtsch Med Wochenschr 2021; 146(13/14): 865-873
DOI: 10.1055/a-1271-2013
Dossier

Vaskuläre Ophthalmopathien – eine interdisziplinäre Aufgabe

Vascular ophthalmopathies – an interdisciplinary task
Martin Middeke
,
Moritz Nasemann
,
Joachim Nasemann

Die retinale Perfusion ist in hohem Maße abhängig von den Determinanten im großen Kreislauf und besonders von der zirkadianen Blutdruckvariabilität und dem nächtlichen Blutdruck – nicht nur bei arterieller Hypertonie. Wegen der näheren Beziehung zum Auge hat der zentrale aortale Blutdruck größere Bedeutung als der konventionell in der Brachialarterie ermittelte Blutdruck. Morphologische und funktionelle Veränderungen der retinalen Gefäße werden heute mit der digitalen Bildgebung in hoher Auflösung erfasst.

Abstract

Retinal microvascular function is highly depending on macrovascular circulation and especially on blood pressure variability and nocturnal blood pressure. The eyes are more subject to central hemodynamics compared to peripheral pressures. Pulse wave analysis is essential here and can reveal masked aortic hypertension. Morphological and functional changes of retinal vessels are detected today in high resolution by digital imaging techniques. Early hypertensive changes can be visualized best by laser scanning multi-color devices, and the vessel diameters (AV-Ratio) are measured precisely by static vessel analysis. Functional disorders of vascular motility are delineated reproducibly by devices for dynamic vessel analysis. Also functional effects of cardiovascular therapy measures can be judged by these means: micro- meets macrocirculation.



Publication History

Article published online:
13 July 2021

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