Appl Clin Inform 2017; 08(01): 206-213
DOI: 10.4338/ACI-2016-09-RA-0156
Research Article
Schattauer GmbH

Electronic Alerts Improve Immunization Rates in Two-month-old Premature Infants Hospitalized in the Neonatal Intensive Care Unit

Kimberly D. Ernst
1   Department of Pediatrics, Section of Neonatal-Perinatal Medicine, The University of Oklahoma, Oklahoma City, OK, USA
› Author Affiliations
Further Information

Publication History

Received: 14 September 2016

Accepted: 11 March 2016

Publication Date:
20 December 2017 (online)

Summary

Objective: To determine if an electronic alert improves 2 month immunization rates in infants remaining hospitalized in the neonatal intensive care unit.

Methods: Institutional Review Board-approved retrospective chart review of 261 infants with birth weights <2 kg and still hospitalized at58 days. Charts were reviewed between 2009 and 2013, before and after the 2011 electronic alert was instituted in the electronic medical record from days 56 to 67 to remind providers that immunizations were due. Order and administration dates of two-month vaccine components (Diphtheria, Haemophilus influenza B, Hepatitis B Pertussis, Pneumococcal, Polio, Tetanus) were determined, and infants were considered fully immunized, partially immunized, or unimmunized by day 90 or discharge, whichever came first.

Results: After the alert, the timing of vaccine orders decreased from day 67 to day 61 (p<0.0001) and vaccine administration decreased from day 71 to day 64 (p<0.0001). Missing vaccine orders decreased from 14% [17/121] to 3% [4/140] (p=0.001) with missing administrations decreasing from 21% [26/121] to 4% [6/140] (p<0.0001). Fully immunized rates increased from 71% [86/121] to 94% [132/140] (p<0.0001).

Conclusions: A significant improvement in immunization rates in two-month-old infants in the neonatal intensive care unit occurred by 90 days after implementing an alert in the electronic medical record.

 
  • References

  • 1 Saari TN; American Academy of Pediatrics Committee on Infectious Diseases.. Immunization of preterm and low birth weight infants. Pediatrics 2003; 112 1 pt 1 193-198.
  • 2 Shah SI. Immunization issues in preterm infants: pertussis, influenza, and rotavirus. Neoreviews 2014; 15: e439-e48.
  • 3 Batra JS, Eriksen EM, Zangwill KM, Lee M, March SM, Ward JI. Evaluation of vaccine coverage for low birth weight infants during the first year of life in a large managed care population. Pediatrics 2009; 123 (Suppl. 03) 951-958.
  • 4 Guerra FA. Delays in immunization have potentially serious health consequences. Paediatr Drugs 2007; 9 (Suppl. 03) 143-148.
  • 5 Maslove DM, Rizk N, Lowe HJ. Computerized physician order entry in the critical care environment: a review of current literature. J Intensive Care Med 2011; 26 (Suppl. 03) 165-171.
  • 6 Scheepers-Hoeks AM, Grouls RJ, Neef C, Ackerman EW, Korsten EH. Physicians’ responses to computer decision support on an ICU—comparison of four different alerting methods. Artif Intell Med 2013; 59 (Suppl. 01) 33-38.
  • 7 Chused AE, Juperman GJ, Stetson PD. Alert override reasons: a failure to communicate. AMIA Annu Symp Proc 2008; 111-115.
  • 8 Khalifa M, Zabani I. Improving utilization of clinical decision support systems by reducing alert fatigue: strategies and recommendations. Stud Health Technol Inform 2016; 226: 51-54.
  • 9 Jacques PS, Rothman B. Enhancing point of care vigilance using computers. Anesthesiol Clin 2011; 29 (Suppl. 03) 505-519.
  • 10 Fiks AG, Grundmeier RW, Biggs LM, Localio AR, Alessandrini EA. Impact of clinical alerts within an electronic health record on routine childhood immunization in an urban pediatric population. Pediatrics 2007; 120 (Suppl. 04) 707-714.
  • 11 Au L, Oster A, Yeh GH, Magno J, Paek HM. Utilizing an electronic health record system to improve vacci-nation coverage in children. Appl Clin Inform 2010; 1 (Suppl. 03) 221-231.
  • 12 Pollack AH, Kronman MP, Zhou C, Zerr DM. Automated screening of hospitalized children for influenza vaccination. J Pediatric Infect Dis Soc 2014; 3 (Suppl. 01) 7-14.
  • 13 Navar-Boggan AM, Halsey NA, Escobar GJ, Golden WC, Klein NP. Underimmunization at discharge from the neonatal intensive care unit. J Perinatol 2012; 32 (Suppl. 05) 363-367.
  • 14 Macintosh JL, Huggins LJ, Eden LM, Merrill KC, Luthy KE. Immunization status of NICU graduates at a tertiary care children’s hospital.. Adv Neonatal Care. 2016 [epub ahead of print]
  • 15 Tozzi AE, Gesualdo F, D’Ambrosio A, Pandolfi E, Agricola E, Lopalco P. Can digital tools be used for improving immunization programs?. Front Public Health 2016; 4: 36.