Synthesis 2017; 49(14): 3084-3090
DOI: 10.1055/s-0036-1588835
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© Georg Thieme Verlag Stuttgart · New York

Palladium-Catalyzed Synthesis of 2-Aminobenzothiazoles through Tandem Reaction

Wan Xua, Meng-Tian Zenga, Min Liua, Sha-Sha Liua, Yue-Sheng Lib, Zhi-Bing Dong*a
  • aSchool of Chemistry and Environment Engineering, Wuhan Institute of Technology, 430074, P. R. of China   Email: dzb04982@wit.edu.cn
  • bNonpower Nuclear Technology Collaborative Innovation Center, Hubei University of Science & Technology, Xianning 437100, P. R. of China
We thank the following for financial support: The National Natural Science Foundation of China (21302150, 11405050), Hubei Provincial Department of Education (D20131501), Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry [2012]1707, President Foundation of Wuhan Institute of Technology (2014038), the Foundation of Chutian Distinguished Fellow from Hubei Provincial Department of Education, and the Foundation of High-End Talent Cultivation Program from Wuhan Institute of Technology.
Further Information

Publication History

Received: 18 March 2017

Accepted after revision: 24 April 2017

Publication Date:
24 May 2017 (eFirst)

Abstract

A variety of 2-aminobenzothiazoles were synthesized by using 2-chloroanilines and dithiocarbamates through a tandem approach in the presence of Pd(PPh3)4 and t-BuOK. The facile and efficient protocol enabled the reaction to proceed at a good rate with excellent yields.

Supporting Information

 
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