Appl Clin Inform 2023; 14(04): 743-751
DOI: 10.1055/a-2121-8380
Research Article

Doctors Identify Hemorrhage Better during Chart Review when Assisted by Artificial Intelligence

Authors

  • Martin S. Laursen*

    1   SDU Robotics, The Maersk Mc-Kinney Moller Institute, University of Southern Denmark, Odense, Denmark
  • Jannik S. Pedersen*

    1   SDU Robotics, The Maersk Mc-Kinney Moller Institute, University of Southern Denmark, Odense, Denmark
  • Rasmus S. Hansen

    2   Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark
  • Thiusius R. Savarimuthu

    1   SDU Robotics, The Maersk Mc-Kinney Moller Institute, University of Southern Denmark, Odense, Denmark
  • Rasmus B. Lynggaard

    2   Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark
  • Pernille J. Vinholt

    2   Department of Clinical Biochemistry, Odense University Hospital, Odense, Denmark

Funding This work was supported by The Odense University Hospital Innovation Fund.
Preview

Abstract

Objectives This study evaluated if medical doctors could identify more hemorrhage events during chart review in a clinical setting when assisted by an artificial intelligence (AI) model and medical doctors' perception of using the AI model.

Methods To develop the AI model, sentences from 900 electronic health records were labeled as positive or negative for hemorrhage and categorized into one of 12 anatomical locations. The AI model was evaluated on a test cohort consisting of 566 admissions. Using eye-tracking technology, we investigated medical doctors' reading workflow during manual chart review. Moreover, we performed a clinical use study where medical doctors read two admissions with and without AI assistance to evaluate performance when using and perception of using the AI model.

Results The AI model had a sensitivity of 93.7% and a specificity of 98.1% on the test cohort. In the use studies, we found that medical doctors missed more than 33% of relevant sentences when doing chart review without AI assistance. Hemorrhage events described in paragraphs were more often overlooked compared with bullet-pointed hemorrhage mentions. With AI-assisted chart review, medical doctors identified 48 and 49 percentage points more hemorrhage events than without assistance in two admissions, and they were generally positive toward using the AI model as a supporting tool.

Conclusion Medical doctors identified more hemorrhage events with AI-assisted chart review and they were generally positive toward using the AI model.

Data Sharing Statement

We cannot make data publicly available due to sensitive information, but we encourage researchers to contact us for sharing possibilities.


Protection of Human and Animal Subjects

This study only included EHR data that were stored and processed on a secure platform in compliance with the General Data Protection Regulations. The study was approved by The Danish Data Protection Agency at the OUH (Journal nr 21/25172) and the regional secretary and Law Department in the Region of Southern Denmark (Journal nr 21/22013). According to section 14(2) of the Danish Act on Research Ethics Review of Health Research Projects, studies using retrospective data that do not involve human biological material do not require ethical approval.


Ethics

The study was approved by The Danish Data Protection Agency at the OUH (Journal nr 21/25172) and the Regional Secretary and Law Department in the Region of Southern Denmark (Journal nr 21/22013).


* Equal contribution.


Supplementary Material



Publikationsverlauf

Eingereicht: 04. April 2023

Angenommen: 29. Juni 2023

Accepted Manuscript online:
03. Juli 2023

Artikel online veröffentlicht:
20. September 2023

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