Enantioselective Conjugate Allylation of Activated a,b-Enones

Significance

Even though there are several highly effective protocols for the addition of allylsilanes to carbonyl compounds, the methods for asymmetric 1,4-addition are still rare. In this report by Snapper’s group a highly efficient method for the introduction of an allyl group in an asymmetric 1,4-addition manner is described. The reaction proceeds under mild conditions to provide products in high yield and moderate to high enantioselectivities.