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Synlett 2001; 2001(12): 1959-1961
DOI: 10.1055/s-2001-18780
DOI: 10.1055/s-2001-18780
letter
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Powerful Stereoselective Aldol-type Additions of Phenyl and Phenylthio Esters with Aldehydes or Ketones Mediated by TiCl4/Amine Reagent
Further Information
Publication History
Publication Date:
04 December 2001 (online)
An efficient TiCl4/amine-promoted aldol-type addition of phenyl and phenylthio esters with aldehydes or ketones has been performed. The present method includes a practical merit from the green chemical viewpoint with regard to yields, variations of substrates, availability of reagents, and simple operations.
aldol reactions - titanium - stereoselectivity - esters - amines