Download PDF
Synlett 2001; 2001(3): 0388-0390
DOI: 10.1055/s-2001-11384
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Readily Prepared Resin-Bound Thioimidates as Reagents for the Synthesis of Amidines

Antonella Ursini* , Monica Delpogetto, Giuseppe Guercio, Alcide Perboni, Tino Rossi
  • *GlaxoWellcome S.p.A. Chemical Development Department, Via A. Fleming 4, 37135 Verona, Italy; E-mail: au4438@GlaxoWellcome.co.uk
Further Information

Publication History

Publication Date:
31 December 2001 (online)

  PDF Download  Permissions and Reprints All articles of this category

The use of commercially available resins to prepare novel and stable polymer supported thioimidates was investigated. Polymer supported thioimidates were found to enable acetamidine formation in a convenient manner, with a significantly easier work-up than solution-phase reactions.

amine - acetamidine - scale-up - solid-phase synthesis - polymers

      >