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Synthesis 1994; 1994(10): 1029-1031
DOI: 10.1055/s-1994-25630
short paper
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Enantioconvergent Route to a Functionalized Quinane System

Takehiko Yoshimitsu* , Yukio Ohshiba, Kunio Ogasawara
  • *Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-77, Japan
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Publication History

Publication Date:
27 September 2002 (online)

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Enantioconvergent route to both enantiomers of a functionalized quinane, methyl 6-oxo-cis-bicyclo[3.3.0]oct-7-ene-3-endo-carboxylate, has been developed by employing lipase-mediated resolution and Wharton rearrangement.

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