Download PDF
Synlett 1990; 1990(10): 615-616
DOI: 10.1055/s-1990-21186
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of 2,8-Substituted 1,7-Dioxa- and 1,4,7,10-Tetraoxaspiro[5.5]undecanes by an Oxyamination Reaction

Marielle Lemaire* , Jean-Gabriel Gourcy, Gérard Dauphin, Georges Jeminet
  • *Université Blaise Pascal (Clermont-II), Laboratoire de Chimie Organique Biologique, U.R.A. 485 du C.N.R.S., F-63177 Aubière Cedex, France
Further Information

Publication History

Publication Date:
08 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

The application of the oxyamination reaction (aminohydroxy addition to an olefin) on 1,10-undecadien-6-one (1) and the corresponding 4,8-dioxa derivative 5 is studied for the synthesis of 2,8-RNHCH2-substituted 1, 7-dioxa- and 1,4,7,10-tetraoxaspiro[5.5]undecanes. The four spiro bicyclic compounds obtained 3a, 8a (R =Ts) and 3b, 8b (R = Cbz), can serve as substrates for further synthetic steps.

      >