Download PDF
Synlett 1990; 1990(7): 423-424
DOI: 10.1055/s-1990-21115
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Facile Cyclodehydrations of Diols and Amino Alcohols with Phosphonium Anhydrides

James B. Hendrickson* , Md. Sajjat Hussoin
  • *Department of Chemistry, Brandeis University, Waltham, Massachusetts 02254-9110, USA
Further Information

Publication History

Publication Date:
08 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

Cyclic ethers and amines with 3-, 5- and 6-membered rings are easily formed from the corresponding diols or amino alcohols, using triphenylphosphonium anhydride ((Ph3P+)2O, 2OTf-]. The reagent is simply prepared in situ from triphenylphosphonium oxide and trifluoromethanesulfonic anhydride, and the cyclodehydration generally proceeds in good yield at room temperature.

      >