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Synthesis 1987; 1987(12): 1130-1133
DOI: 10.1055/s-1987-28198
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Synthesis of 4-Functionalized 1-Ethoxycarbonyl-2-oxo-3-oxabicyclo[3.1.0]hexanes by Reformatsky Reaction

Françoise Gaudemar-Bardone* , Marcel Gaudemar, Margarita Mladenova
  • *Université Pierre et Marie Curie, Laboratoire de Synthèse Organométallique, Bâtiment F, 4, Place Jussieu, F-75230 Paris Cedex 05, France
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Publication Date:
20 August 2002 (online)

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The title compounds are easily synthesized in good yields by reaction of the Reformatsky reagents derived from α-bromesters, α-bromocarboxamides, and α-bromonitriles with 2-acyl-3-phenyl(or 3-alkyl)-1,1-diethoxycarbonylcyclopropanes.

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