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Synthesis 1986; 1986(8): 683-686
DOI: 10.1055/s-1986-31750
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A New Approach to the Synthesis of Pyrrolizines: A One-pot Procedure from 2H-Pyrroles

P. F. Belloir* , A. Laurent, P. Mison, S. Lesniak, R. Bartnik
  • *Universite Claude Bernard-Lyon 1, Laboratoire de Chimie Organique III. U. A. CNRS 0467, 43, Bd. du 11 Novembre 1918, F-6922 Villeurbanne Cedex, France
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Publikationsdatum:
22. August 2002 (online)

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A convenient method for synthesis of the pyrrolizine nucleus is reported. The pyrrolizines were obtained through 1,3-dipolar cycloaddition on azomethine ylids 4 generated in situ from 2H-pyrroles. The new adducts were characterized by 1H- and 13C-N.M.R. data as well as mass spectrometry.