DOI: 10.1055/s-00000131

Synfacts

Issue 10 · Volume 17 · October 2021 DOI: 10.1055/s-011-51880

Synform

  • A157

    SYNFORM ISSUE 2021/10

    • Synthesis of Natural Products and Potential Drugs

  • z1071

    All PDFs of this category

  • 1071

    Synthesis of Sotorasib

  • 1072

    Synthesis of (+)-Davisinol

  • 1073

    Synthesis of (–)-Talatisamine and (–)-Liljestrandisine

  • 1074

    Synthesis of Anti-Malarial MMV390048

  • 1075

    Total Synthesis (+)-Pepluanol A

  • 1076

    Synthesis of Pemigatinib

  • 1077

    Total Synthesis of (+)-Ambiguine G

  • 1078

    Synthesis of (+)-Mannolide C

  • 1079

    Total Synthesis of (+)-Prostratin

  • 1080

    Synthesis of (±)-Pentacycloanammoxic Acid Methyl Ester

    • Synthesis of Heterocycles

  • z1081

    All PDFs of this category

  • 1081

    Synthesis of Silazacycles from the Elusive 3-Silaazetidine

  • 1082

    Synthesis of 2,1-Benzisoxazoles via Decyanative Cyclization

  • 1083

    Direct Preparation of N-Substituted Pyrazoles from Primary Aliphatic or Aromatic Amines

  • 1084

    Dithioesters as Thiocarbonyl Precursors in Thorpe–Ziegler-Type Cyclization

  • 1085

    Regiospecific Three-Component Synthesis of 2-Aminothiophenes

  • 1086

    Rh-Catalyzed Synthesis of Thienoacenes from Thiophenes

  • 1087

    Direct C–H Functionalization of N-Heteroaromatics with Cyclic Ethers

    • Synthesis of Materials and Unnatural Products

  • z1089

    All PDFs of this category

  • 1089

    Dendritic Donor for Good π-Stacking

  • 1090

    A Tetrathia[8]circulene–Azaborine Fusion

  • 1091

    Living Helix

  • 1092

    Synthesis of Stereogenic Fluoroborate as a Fluorophore with an Increased Stokes Shift

  • 1093

    Nitrogen Incorporation in a Nanographene through Direct Oxidative Cyclization

  • 1094

    A Benzene- Bridged Bismacrocycle

  • 1095

    Metal-Free Oxidative Decarboxylative Coupling

  • 1096

    Easy Access to a Nitrogen- Doped Aromatic Belt with a [6]Cycloparaphenylene Skeleton

  • 1097

    Efficient Synthesis of a Novel Benzo-Incorporated Smallest Expanded Calix[4]pyrrole

  • 1098

    A New Meta in meta-Halophenol Synthesis

  • 1099

    Thiolated Pillar[5]arene and Its Supramolecular-Complexation-Accelerated Dimerization

  • 1100

    Calix[3]-Type Macrocycles: The Missing Family Member

    • Metals in Synthesis

  • z1101

    All PDFs of this category

  • 1101

    Denitrogenative Ring Shrinkage of Heterocycles

  • 1102

    Synthesis of Chiral Cyclopropane-1-Carboxylates

  • 1103

    One-Pot α,α′-Difunctionalization of Cyclic Amines

  • 1104

    Trifluoroacetylation of Styrenes

  • 1105

    Copper-Catalyzed Arene Ring Cleavage

  • 1106

    Enantioselective Rhodium-Catalyzed Synthesis of Fluorinated Allenes

  • 1107

    Iron-Catalyzed Cross-Coupling of Propargyl Ethers with Grignard Reagents

  • 1108

    Stereoselective Synthesis of (E)-δ-Vinyl-Homoallylic Alcohols from α-Vinyl Allylboronate

  • 1109

    Preparation of Chiral Allylic Alcohols by Asymmetric Reduction of Substituted Cycloalkenones

  • 1110

    Vinylation of Aldehydes through Twofold C–H Functionalization

  • 1111

    Rhodium-Catalyzed Alkynylcyclopropanation of Alkenes Using Alkynylcycloheptatrienes

  • 1112

    Iridium-Catalyzed Alkenylation of Enamides

  • 1113

    Preparation of (Het)arylgermanes

  • 1114

    Palladium and Ammonium Halide Catalysis for Enantioselective [4+2] Annulations

  • 1115

    Enantio- and Diastereoselective Synthesis of Trifluoromethyl-Cyclopropylboronates

  • 1116

    Directed Nickel-Catalyzed Hydrofunctionalization of Alkenes

  • 1117

    Synthesis of gem-Difluorohomoallylic Alcohols by Reductive Defluorinative Coupling

  • 1118

    Palladium-Catalyzed Benzylic C(sp3)–H Carbonylative Arylation of Azaarylmethyl Amines

  • 1119

    Nickel-Catalyzed Ring-Opening Allylation of Cyclopropanols with Allylic Carbonates

  • 1120

    Rhodium-Catalyzed Stereoselective Synthesis of Enones and Enals from 2,3-Allenols and Organoboronic Acids

  • 1121

    Copper-Catalyzed Amination of Secondary Alkyl Iodides

  • 1122

    Stereodivergent Aldehyde α-Allylation with 1,3-Dienes

  • 1123

    Palladium-Catalyzed Dearomatization of Nitroindoles

  • 1124

    Palladium-Catalyzed Carbonylative-Amination Reaction Generating Fluorinated β-Lactams

  • 1125

    Regiodivergent Hydroalkenylation of 1,6-Enynes with Acrylates and Alkenes

  • 1126

    Nickel-Catalyzed Cross-Coupling of α-Magnesiated Nitriles by Using a Benzonitrile Ligand

    • Polymer-Supported Synthesis

  • z1127

    All PDFs of this category

  • 1127

    Selective Synthesis of Imines and Secondary Amines by Homocoupling of Primary Amines

  • 1128

    Cobalt-Catalyzed Synthesis of Tetrahydropyridine Derivatives and Oxidation of Benzylic Alcohols

  • 1129

    Zirconium Metal–Organic Framework Catalyzed Direct Amide-Bond Formation

  • 1130

    Hydrogenation of Quinolines Catalyzed by Tungsten- Doped Cobalt Nanoparticles

  • 1131

    N-Alkylation of Amines with Aldehydes Catalyzed by a Graphene-Co-Shelled Ni/NiO@C Nanocatalyst

  • 1132

    Synthesis of Pyrans by a Zirconium-Catalyzed Three-Component Condensation

  • 1133

    Ruthenium-Catalyzed Transformations of 2,5-Hexanediones into Furans or Pyrrolidines

  • 1134

    Controlled Hydrogenation of Azoarenes to Hydrazoarenes on Palladium/Carbon

  • 1135

    Aerobic Oxidation of α-Diazo Esters Catalyzed by Charcoal-Supported Copper Nanoparticles

  • 1136

    Palladium-Catalyzed α-Arylation of Ketones in Water

    • Organo- and Biocatalysis

  • z1137

    All PDFs of this category

  • 1137

    Biocatalytic Directed Cationic Cyclization Cascades toward Fragrance Ingredients

  • 1138

    Carbon-Bonding Interaction Catalyst

  • 1139

    Organocatalytic Enantiodivergent Bromolactonizations

  • 1140

    Development of a Novel Chiral Framework: The SPHENOL Backbone

  • 1141

    Synthesis of Chiral Cyclazines by Aminocatalytic Stereoselective [8+2] Cycloaddition

  • 1142

    Protecting Group-Free Late-Stage S-Glycosylation of Peptides

  • 1143

    Visible-Light Photoredox-Catalytic Coupling of Aryl Chlorides via Radical Anions

  • 1144

    Organocatalytic Kinetic Resolution of Amido Tertiary Allylic Alcohols

  • 1145

    Cinchona-Alkaloid-Catalyzed Annulation Enables an Asymmetric Synthesis of Chiral Oxacycles

  • 1146

    Chiral Triazolium Salt-Catalyzed Asymmetric Cyanoalkylation of Electron-Deficient Olefins

    • Chemistry in Medicine and Biology

  • z1147

    All PDFs of this category

  • 1147

    Aziridines Cross-Dimerize to Larger N-Heterocycles

  • 1148

    Photocatalyzed Site-Selective Tyrosine Bioconjugation

  • 1149

    Doubly Caged Puromycin

  • 1150

    A Novel P(V)-Based Reagent for Asymmetric Synthesis of Thiophosphoramidates

  • 1151

    Eschenmoser Sulfide Contraction in the Synthesis of Kinase Inhibitors

  • 1152

    Gram-Scale Synthesis of Iboxamycin

  • 1153

    Optical Control of Phosphatidic Acid Signaling

  • 1154

    Beating Resistant Plasmodium Parasites with the Antimalarial MMV688533

  • 1155

    Potent and Selective Orphan GPCR Agonist for the Treatment of Schizophrenia

  • 1156

    Activity-Based Probe for Monitoring Ethylene

  • 1157

    Optical Control of Sodium Channels

  • 1158

    A Rigid Vitamin Diet: Allenic derivatives of Vitamin D

    • Peptide Chemistry

  • z1159

    All PDFs of this category

  • 1159

    Organoboron-Catalyzed Synthesis of Serine- and Threonine-Derived Weinreb Amides

  • 1160

    Palladium-Catalyzed C–H Functionalization of Cyclic-Aminal-Protected Peptides

  • 1161

    Synthesis of Sulfonyl Fluoro Peptides by an Ugi Reaction

  • 1162

    Unnatural Peptide Synthesis by Photochemical Acyl Radical Addition of Dehydroalanine

  • 1163

    Palladium-Catalyzed Modification of Aspartic Acid-Containing Peptides

  • 1164

    Electrochemical Synthesis of α-Amino Esters

  • 1165

    Enantioselective Synthesis of 2-Chloroaziridines

  • 1166

    Chiral Phosphoric Acid-Catalyzed Synthesis of α-Amino Esters

  • 1167

    Ruthenium-Catalyzed Dehydrogenative Amidation of Alcohols by Amines

  • 1168

    Unnatural α-Amino Acid Synthesis by Photoinduced Alkylation of Dehydroalanine

  • 1169

    Synthesis of a Side-Chain-Tethered Solid Support for Peptide Synthesis

  • 1170

    Synthesis of γ-Oxo-α-Amino Acids by Iridium Catalysis

    • Flow Chemistry

  • z1171

    All PDFs of this category

  • 1171

    Photocatalytic C(sp3)–H Heteroarylation in Flow

  • 1172

    Decarboxylation and Decarboxylative Deuteration of Carboxylic Acids by Using a Ag–Bi Hybrid Material

  • 1173

    A Fixed-Bed Approach for Wittig-Type Olefinations in Continuous Flow

  • 1174

    Ozone-Mediated Oxidation of Amines and Pyridines under Flow Conditions