Applied Clinical Informatics, Table of Contents Appl Clin Inform 2014; 05(01): 25-45DOI: 10.4338/ACI-2013-08-RA-0057 Research Article Schattauer GmbH Analysis Of Electronic Medication Orders With Large OverdosesOpportunities For Mitigating Dosing Errors E.S. Kirkendall 1 Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio 2 Department of Information Services, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio 3 Division of Hospital Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio 4 James M. Anderson Center for Health Systems Excellence, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio , M. Kouril 1 Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio , T. Minich 2 Department of Information Services, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio 5 Division of Pharmacy, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio , SA. Spooner 1 Division of Biomedical Informatics, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio 2 Department of Information Services, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio 3 Division of Hospital Medicine, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio› Author AffiliationsRecommend Article Abstract Full Text PDF Download Keywords KeywordsElectronic health record - electronic medical record - medical order entry system - CPOE - clinical decision support systems References References 1 Caldwell NA, Power B. The pros and cons of electronic prescribing for children. Arch Dis Child 2012; 97 (02) 124-128. 2 Wong IC. et al. Incidence and nature of dosing errors in paediatric medications: a systematic review. Drug Saf 2004; 27 (09) 661-670. 3 McPhillips H. et al. Methodological challenges in describing medication dosing errors in children, in advances in patient safety: from research to implementation. (Volume 2: Concepts and Methodology), K. Henriksen, et al., Editors. 2005 Rockville (MD). 4 Conroy S. et al. Interventions to reduce dosing errors in children: a systematic review of the literature. Drug Saf 2007; 30 (12) 1111-1125. 5 Ginzburg R. et al. Effect of a weight-based prescribing method within an electronic health record on prescribing errors. Am J Health Syst Pharm 2009; 66 (22) 2037-2041. 6 Jani YH, Barber N, and Wong IC. Paediatric dosing errors before and after electronic prescribing. Qual Saf Health Care 2010; 19 (04) 337-340. 7 McPhillips HA. et al. Potential medication dosing errors in outpatient pediatrics. J Pediatr 2005; 147 (06) 761-767. 8 Maat B. et al. Clinical pharmacy interventions in paediatric electronic prescriptions. Arch Dis Child; 2013; 98 (03) 222-227. 9 Isaac TJ. et al. Overrides of medication alerts in ambulatory care. Arch Intern Med 2009; 169 (03) 305-311. 10 van der Sijs H. et al. Turning off frequently overridden drug alerts: limited opportunities for doing it safely. J Am Med Inform Assoc 2008; 15 (04) 439-448. 11 Lin CP. et al. Evaluating clinical decision support systems: Monitoring CPOE order check override rates in the Department of Veterans Affairs’ Computerized Patient Record System. J Am Med Inform Assoc 2008; 15 (05) 620-626. 12 del Beccaro MA. et al. Decision support alerts for medication ordering in a computerized provider order entry (CPOE) system. Applied Clinical Informatics 2010; 1 (03) 346-362. 13 Kirkendall ES, Spooner SA, Logan JR. Evaluating the accuracy of electronic pediatric drug dosing rules. J Am Med Inform Assoc. 2013 Jun 28. [Epub ahead of print] 14 Barrett JS. et al. Prescribing habits and caregiver satisfaction with resources for dosing children: rationale for more informative dosing guidance. BMC Pediatr 2011; 11: 25. 15 Doherty C, Mc Donnell C. Tenfold medication errors: 5 years’ experience at a university-affiliated pediatric hospital. Pediatrics 2012; 129 (05) 916-924. 16 Koren G, Barzilay Z, Greenwald M. Tenfold errors in administration of drug doses: a neglected iatrogenic disease in pediatrics. Pediatrics 1986; 77 (06) 848-849. 17 Monagle P, Studdert DM, Newall F. Infant deaths due to heparin overdose: time for a concerted action on prevention. J Paediatr Child Health 2012; 48 (05) 380-381. 18 Gerstle RS, Lehmann CU. Electronic prescribing systems in pediatrics: the rationale and functionality requirements. Pediatrics 2007; 119 (06) e1413-e1422. 19 Kim G, Lehmann C. Pediatric aspects of inpatient health information technology systems. Pediatrics 2008; 122 (06) e1287-e1296. 20 Spooner SA. Special requirements of electronic health record systems in pediatrics. Pediatrics 2007; 119 (03) 631-763. 21 ANSI.. HL7 EHR Child Health Functional Profile, Release 1. 2008 12/10/2008 [cited 2013 8/1/2013]; ANSI/HL7 EHR CHFP, R1–2008:[Available from: http://www.hl7.org/implement/standards/product_brief.cfm?product_id=15.