Abstract
The intermolecular reductive cyclodimerization reactions of cyclic α,β-unsaturated
ketones such as 2-benzylideneindan-1-ones, 2-benzylidene-1-tetralones, 3-benzylidenechroman-4-ones,
and 3-benzylidenethiochroman-4-ones induced by a low-valent titanium reagent were
studied. Some new spiro compounds were prepared in good yields under neutral and mild
conditions. High stereoselectivity was achieved and the stereochemistry of the products
was confirmed by X-ray diffraction analysis.
Key words
low-valent titanium - cyclic α,β-unsaturated ketones - spiro compounds - stereochemistry
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