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Synthesis 2006(14): 2413-2417
DOI: 10.1055/s-2006-942449
DOI: 10.1055/s-2006-942449
PAPER
© Georg Thieme Verlag Stuttgart · New YorkA Facile Synthesis of 1-Phenylsulfonyl-3-substituted-2-cyanoindoles, 1-Phenylsulfonyl-2-methyl-3-cyanoindoles, and Bifunctional 1-Phenylsulfonylindoles
Further Information
Received
2 November 2005
Publication Date:
29 June 2006 (online)
Publication History
Publication Date:
29 June 2006 (online)
Abstract
A facile ‘one-pot’ introduction of the cyano group into the 2/3-position of indole has been developed from the corresponding aldehydes using anhydrous aluminum chloride and sodium azide.
Key words
indole aldehydes - aluminum chloride - sodium azide - cyanoindoles - bifunctional indoles
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