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Synthesis 2004(18): 3092-3096
DOI: 10.1055/s-2004-829192
DOI: 10.1055/s-2004-829192
PSP
© Georg Thieme Verlag Stuttgart · New YorkHighly Diastereoselective Synthesis of β-Hydroxy Amides from β-Keto Amides
Further Information
Received
1 June 2004
Publication Date:
13 August 2004 (online)
Publication History
Publication Date:
13 August 2004 (online)

Abstract
β-Hydroxy amides with stereodefined geometry represent an important unit present in various natural products. The diastereoselective preparation of amides carrying a secondary or tertiary alcohol in β-position is described here.
Key words
diastereoselectivity - hydroxy amides - TiCl4 - organocerium reagents - boranes
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