Endoskopische Therapie der gastroösophagealen Refluxkrankheit

Zusammenfassung

Für die Therapie der gastroösophagealen Refluxkrankheit werden derzeit verschiedene neue endoskopische Techniken evaluiert. Diese minimal invasiven endoskopischen Verfahren zielen darauf ab, die Refluxkrankheit durch eine Verbesserung der gastroösophagealen Refluxbarriere zu behandeln. Dies kann auf endoskopischem Wege durch endoluminal platzierbare Nähte, durch Applikation von Radiofrequenzenergie sowie durch Injektion oder Implantation biokompatibler Fremdkörper erreicht werden. Die genannten vielversprechenden Therapiemodalitäten sind allerdings zur Zeit noch nicht für den routinemäßigen Einsatz vorgesehen, sondern müssen erst in laufenden Studien insbesondere hinsichtlich des Langzeiteffektes und möglicher Komplikationen evaluiert werden.

Summary

Various endoscopic techniques are currently evaluated for the treatment of gastro-esophageal reflux disease. These minimally invasive treatment modalities are based on the attempts to improve the gastro-esophageal reflux barrier. By endoscopic means, this can be achieved in various ways: by endoscopically placed endoluminal sutures, application of radiofrequency energy, and finally injection or implantation of biocompatible materials. First results of these endoscopic therapies are promising, however, before they can be considered ready for routine clinical application, ongoing studies have to evaluate long-term effects and potential complications

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