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Dtsch Med Wochenschr 2000; 125(47): 1437-1443
DOI: 10.1055/s-2000-8495
DOI: 10.1055/s-2000-8495
Übersichten
© Georg Thieme Verlag Stuttgart · New YorkHerzrhythmusstörungen bei arterieller Hypertonie
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
31. Dezember 2000 (online)
Die arterielle Hypertonie ist eine epidemiologisch bedeutsame Erkrankung mit einer Prävalenz von etwa 15 % [44] . Sie stellt einen eigenständigen Risikofaktor für die Entwicklung einer koronaren Herzerkrankung, das Auftreten von ventrikulären Arrhythmien oder das Eintreten eines plötzlichen Herztodes dar. Mit steigenden Blutdruckwerten steigt auch das kardiovaskuläre Mortalitätsrisiko [36] . Insbesondere bei zusätzlich bestehender linksventrikulärer Hypertrophie ist die Prognose verschlechtert [22]. Die linksventrikuläre Hypertrophie war lange Zeit als ein kompensatorischer Prozess gewertet worden und nicht als Risikofaktor für lebenbedrohliche Arrhythmien. Es ist aber mittlerweile bewiesen, dass die linksventrikuläre Hypertrophie einen in sich pathologischen Prozess darstellt mit Störungen der Diastole, der Koronarreserve und dem Auftreten ventrikulärer Ektopien. Die vorliegende Arbeit soll eine Übersicht geben über die bei einer arteriellen Hypertonie vorkommenden Arrhythmien.
Literatur
- 1
Aguilar J C, Martinez A H, Conejos F A.
Mechanisms
of ventricular arrhythmias in the presence of pathological hypertrophy.
Eur
Heart J.
1993;
14
(J)
65-70
MissingFormLabel
- 2
Algra A, Tijssen J GP, Roelandt J RTC, Pool J, Lubsen J.
Heart rate variability
from 24-hour electrocardiography and the 2-year risk for sudden
cardiac death.
Circulation.
1993;
88/1
180-185
MissingFormLabel
- 3
Aronson R S.
Afterpotentials
and triggered activity in hypertrophied myocardium from rats with
renal hypertension.
Circ Res.
1981;
48
720-727
MissingFormLabel
- 4
Bayés de Luna A, Prat X V, Guindo J.
Ventricular
arrhythmias in left ventricular hypertrophy and heart failure.
Eur
Heart J.
1993;
14
(J)
62-64
MissingFormLabel
- 5
Bethge C, Motz W, von Hehn A, Strauer B E.
Ventricular
arrhythmias in hypertensive heart disease with and without heart
failure.
J Cardiovasc Pharmacol.
1987;
10
(6)
S119-S128
MissingFormLabel
- 6
Breithardt G, Cain M, El-Sherif N, Flowers N C.
Standards
for analysis of ventricular late potentialsusing high-resolution
or signal-averaged electrocardiography. A statement by a task force
committee of the European Society of Cardiology, the American Heart Association
and the American College of Cardiology.
Circulation.
1991;
83
1481-1486
MissingFormLabel
- 7
Cameron J S, Myerburg R J, Wong S S, Gaide M S, Epstein K, Alvarez T R, Gelband H, Guse P A, Bassett A L.
Electrophysiologic
consequences of chronic experimentally induced left ventricular
pressure overload.
J Am Coll Cardiol.
1983;
2
481-487
MissingFormLabel
- 8
Clementy J, Safar M, Vrancea F.
Cardiac
arrhythmias in hypertension. Prospective study including 251 patients.
Efficacy of sotalol.
Eur Heart J (Abstr.).
1989;
10
201
MissingFormLabel
- 9
Corbalán R, Arriagada D, Braun S, Tapia J, Heute I, Kramer A, Chávez A.
Risk factors
for systemic embolism in patients with paroxysmal atrial fibrillation.
Am
Heart J.
1992;
124
149-153
MissingFormLabel
- 10
Dominguez G, Fozzard H.
Effect of strech on
conduction velocity and cable properties of Purkinje fibers.
Am
J Physiol.
1979;
138
273-282
MissingFormLabel
- 11
ESVEM Investigators .
Determinants
of predicted efficacy of antiarrhythmic drugs in the Electrophysiologic
Study Versus Electrocardiographic Monitoring trial.
Circulation.
1993;
87
323-329
MissingFormLabel
- 12
Galinier M, Balanescu S, Fourcade J, Dorobantu M, Albenque J P, Massabuau P, Doazan J P, Fauvel J M, Bounhoure J P.
Prognostic
value of arrhythmigenic markers in systemic hypertension.
Eur Heart
J.
1997;
18
1484-1491
MissingFormLabel
- 13
Galinier M, Balanescu S, Fourcade J, Dorobantu M, Boveda S, Massbuau P, Cabrol P, Dongay B, Fauvel J M, Bounhoure J P.
Prognostic value
of ventricular arrhythmias in systemic hypertension.
J
Hypertension.
1997;
15
1779-1783
MissingFormLabel
- 14
González-Juanatey J R, García-Acuna J M, Pose A, Varela A, Calvo C, Cabezas-Cerrato J, Gil de la Pena M.
Reduction of
QT and QTc dispersion during long-term treatment of systemic hypertension with
enalapril.
Am J Cardiol.
1998;
81
170-174
MissingFormLabel
- 15
Hennersdorf M G, Perings C, Niebch V, Vester E G, Strauer B E.
T-wave
alternans as a risk predictor in patients with cardiomyopathy and
mild to moderate heart failure.
PACE.
2000;
in
press
MissingFormLabel
- 16
Jauch W, Hicks M N, Cobbe S M.
Effects of contraction-excitation feedback
on electrophysiology and arrhythmogenesis in rabbits with experimental
left ventricular hypertrophy.
Cardiovascular research.
1994;
28
1390-1396
MissingFormLabel
- 17
Kannel W B, Abbott R D, Savage D D, McNamara P M.
Epidemiologic features
of chronic atrial fibrillation. The Framingham study.
N Engl
J Med.
1982;
306
1018-1022
MissingFormLabel
- 18
Kannel W B.
Left
ventricular hypertrophy as a risk factor in arterial hypertension.
Eur
Heart J.
1992;
13
(D)
82-88
MissingFormLabel
- 19
Karpanou E A, Vyssoulis G P, Psichogios A, Malakou C, Kyrozi E A, Cokkinos D V, Toutouzas P K.
Regression
of left ventricular hypertrophy results in improvement of QT dispersion
in patients with hypertension.
Am Heart J.
1998;
136
765-768
MissingFormLabel
- 20
Keung E CH, Aronson R S.
Non-uniform
electrophysiologic properties and electronic interaction in hypertrophied
rat myocardium.
Circ Res.
1981;
49
150-158
MissingFormLabel
- 21
Kohya T, Yokoshiki H, Tohse N, Kanno M, Nakaya H, Saito H, Kitabatake A.
Regression
of left ventricular hypertrophy prevents ischemia-induced lethal
arrhythmias. Beneficial effect of angiotensin II blockade.
Circ
Res.
1995;
76
892-899
MissingFormLabel
- 22
Koren M J, Devereux R B, Casale P N, Savage D D, Laragh J H.
Relation of
left ventricular mass and geometry to morbidity and mortality in
uncomplicated essential hypertension.
Ann Int Med.
1991;
114
345-352
MissingFormLabel
- 23
Kowey P R, Friehling T D, Sewter J, Wu Y, Sokil A, Paul J, Nocella J.
Electrophysiological
effects of left ventricular hypertrophy. Effect of calcium and potassium
channel blockade.
Circulation.
1991;
83
2067-2075
MissingFormLabel
- 24
Kulan K, Ural D, Komsuoglu B, Agacdiken A, Göldeli Ö, Komsuoglu S S.
Significance
of QTc prolongation on ventricular arrhythmias in patients with
left ventricular hypertrophy secondary to essential hypertension.
Int
J Cardiol.
1998;
64
179-184
MissingFormLabel
- 25
Le Heuzey J Y, Guize L.
Cardiac prognosis in hypertensive
patients. Incidence of sudden death and ventricular arrhythmias.
Am
J Med.
1988;
84
(1B)
65-68
MissingFormLabel
- 26
Levy D, Anderson K M, Savage D D, Balkus S A, Kannel W P, Castelli W P.
Risk
of venricular arrhythmias in left ventricular hypertrophy: The Framingham
Heart Study.
Am J Cardiol.
1987;
60
560-565
MissingFormLabel
- 27
Levy D, Garrison R J, Savage D D, Kannel W B, Castelli W P.
Prognostic implications
of echocardiographically determined left ventricular mass in the
Framinham heart study.
N Engl J Med.
1990;
322
1561-1566
MissingFormLabel
- 28
Levy D, Salomon M, D’Agostino R B, Belanger A J, Kannel W B.
Prognostic
implications of baseline electrocardiographic features and their
serial changes in subjects with left ventricular hypertrophy.
Circulation.
1994;
90
1786-1793
MissingFormLabel
- 29
McLenachan J M, Henderson E, Morris K I, Dargie K J.
Ventricular
arrhythmias in patients with hypertensive left ventricular hypertrophy.
N
Engl J Med.
1987;
317
787-792
MissingFormLabel
- 30
Messerli F H, Grodzicki T.
Hypertension, left
ventricular hypertrophy, ventricular arrhythmias and sudden death.
Eur
Heart J.
1992;
13
(D)
66-69
MissingFormLabel
- 31
Messerli F H, Nunez B D, Nunez M M, Garavaglia G E, Schmieder R E, Ventura H O.
Hypertension
and sudden death. Disparate effects of calcium entry blocker and
diuretic therapy on cardiac arrhythmias.
Arch Intern Med.
1989;
149
1263-1267
MissingFormLabel
- 32
Messerli F H, Schmieder R E.
Arterielle
Hypertonie, linksventrikuläre Hypertrophie und plötzlicher
Herztod.
Dtsch Med Wschr.
1990;
115
1682-1687
MissingFormLabel
- 33
Perings C, Hennersdorf M, Vester E G, Weirich J, Strauer B E.
Pathophysiologie,
Epidemiologie und Komplikationen des Vorhofflimmerns.
Internist.
1998;
39
2-11
MissingFormLabel
- 34 Perings C. Nicht-invasive
und invasive Risikoerkennung des plötzlichen Herztodes
bei Hypertonikern. Habilitationsschrift, Heinrich-Heine-Universität
Düsseldorf 1997
MissingFormLabel
- 35
Pichard A D, Gorlin R, Smith H, Ambrose J, Meller J.
Coronary flow studies
in patients with left ventricular hypertrophy of the hypertensive
type.
Am J Cardiol.
1981;
47
547-554
MissingFormLabel
- 36
Port S, Demer L, Jennrich R, Walter D, Garfinkel A.
Systolic blood pressure
and mortality.
Lancet.
2000;
355
175-180
MissingFormLabel
- 37
Rials S J, Wu Y, Ford N, Pauletto F J, Abramson S V, Rubin A M, Marinchak R A, Kowey P R.
Effect
of left ventricular hypertrophy and its regression on ventricular
electrophysiology and vulnerability to inducible arrhythmia in the
feline heart.
Circulation.
1995;
91
426-430
MissingFormLabel
- 38
Schannwell C A, Schoebel F C, Badiian M, Jax T W, Marx R, Plehn G, Perings C, Vester E G, Leschke M, Strauer B E.
Diastolische
Funktionsparameter und atriale Rhythmusstörungen bei Patienten
mit arterieller Hypertonie.
Dtsch Med Wschr.
1998;
123
957-964
MissingFormLabel
- 39
Scheler S, Motz W, Strauer B E.
Transiente
Myokardischämien bei Hypertonikern.
Z Kardiol.
1990;
78
197-203
MissingFormLabel
- 40
Sideris D A, Kontoyannis D A, Michalis L, Adractas A, Moulopoulos S D.
Acute
changes in blood pressure as a cause of cardiac arrhythmias.
Eur
Heart J.
1987;
8
45-52
MissingFormLabel
- 41
Siegel D, Cheitlin M D, Black D M, Seeley D E, Hearst N, Hulley S B.
Risk of ventricular
arrhythmias in hypertensive men with left ventricular hypertrophy.
Am
J Cardiol.
1990;
65
742-747
MissingFormLabel
- 42
Sihm I, Sogaard P, Schroeder A P, Aalkjaer C, Mulvany M, Lederballe O, Thygesen K.
Myocardial ischemia
and ventricular arrhythmias in relation to left ventricular mass
and resistance artery structure.
Cardiology.
1997;
88
141-146
MissingFormLabel
- 43
Spach M S, Miller W T, Geselowitz D B, Barr R C, Kootsey J M, Johnson E A.
The discontinous
nature of propagation in normal canine cardiac muscle. Evidence
for recurrent discontinuity of intracellular resistance that affect
the membrane currents.
Circ Res.
1981;
48
39-54
MissingFormLabel
- 44 Strauer B E
(ed). Das Hochdruckherz. Springer-Verlag
Berlin Heidelberg New York Tokyo 1991
MissingFormLabel
- 45
Strauer B E.
The
significance of coronary reserve in clinical heart disease.
J
Am Coll Cardiol.
1990;
15
774-783
MissingFormLabel
- 46
Sugishita Y, Iida K, Yukisada K.
Mechanical
and non-mechanical factors in hypertensive hypertrophy, their clinical
roles.
Japan Circ J.
1990;
54
568-574
MissingFormLabel
- 47
Szlachcic J, Tubau J F, O¿Kelly B, Ammon S, Daiss K, Massie B M.
What
is the role of silent coronary artery desease and left ventricular
hypertrophy in the genesis of ventricular arrhythmias in men with
essential hypertension?.
J Am Coll Cardiol.
1992;
19
803-808
MissingFormLabel
- 48
The Stroke Prevention in
Atrial Fibrillation Investigators .
Predictors of thromboembolism
in atrial fibrillation: I. Clinical features of patients at risk.
Ann
Int Med.
1992;
116
1-5
MissingFormLabel
- 49
The Stroke Prevention in
Atrial Fibrillation Investigators .
Predictors of thromboembolism
in atrial fibrillation: II. Echocardiographic features of patients
at risk.
Ann Int Med.
1992;
116
6-12
MissingFormLabel
- 50
Vester E G, Emschermann C, Stobbe U, Ochiulet-Vester J, Perings C, Kühl U, Schultheiss H P, Pölitz B, Heydthausen M, Strauer B E.
Late potentials
and heart rate variability in heart muscle disease.
Eur Heart
J.
1994;
15
(. C)
25-33
MissingFormLabel
- 51
Vester E G, Kuhls S, Ochiulet-Vester J, Vogt M, Strauer B E.
Electrophysiological
and therapeutic implications of cardiac arrhythmias in hypertension.
Eur
Heart J.
1992;
13
(D)
70-81
MissingFormLabel
- 52
Zehender M, Meinertz T, Hohnloser S, Geibel A, Gerisch I, Olschewski M, Just H.
Prevalence
of circadian variations and spontaneous variability of cardiac disorders
and ECG changes suggestive of myocardial ischemis in systemic arterial
hypertension.
Circulation.
1992;
85
1808-1815
MissingFormLabel
Dr. med. M. Hennersdorf
Medizinische Klinik und Poliklinik B
Klinik für Kardiologie, Pneumologie und Angiologie
Heinrich-Heine-Universität
Moorenstraße 5
40225 Düsseldorf
eMail: hennersd@uni-duesseldorf.de