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Synthesis 2020; 52(01): 1-20
DOI: 10.1055/s-0039-1690684
DOI: 10.1055/s-0039-1690684
review
Recent Advances in Reactions of Propargylamines
We thank the Natural Science Foundation of Zhejiang Province (LQ18B020001) for financial support.Further Information
Publication History
Received: 16 July 2019
Accepted after revision: 02 September 2019
Publication Date:
08 October 2019 (online)
‡ These authors contributed equally.
Abstract
Propargylamines are extremely versatile and common building blocks in the field of chemistry. This review highlights the recent advances made in the reactions of propargylamines between 2009 and 2019. The reaction types are classified into six categories based on the trigger mechanisms: (1) amino moieties as leaving groups, (2) hydrogenation, (3) rearrangement, (4) nucleophilic amines, (5) nucleophilic carbons, and (6) electrophilic alkynes. We hope that this review will promote future research in this area.
1 Introduction
2 Amino Moieties as Leaving Groups
3 Hydrogenation
4 Rearrangement
5 Nucleophilic Amines
6 Nucleophilic Carbons
7 Electrophilic Alkynes
8 Conclusions
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