A strategy has been described to synthesize β,γ-diaminoketones. This strategy is
enabled by photoredox-catalyzed and nitrogen-centered radical-triggered cascade reactions
of styrenes, enamides, and O-acylhydroxylamines in DMSO. Four bonds (one C–C, one C–N, and two C–O) are constructed
in a single operation. Various functionalized vicinal diamines have been furnished
by the radical relay reaction.
Key words
photochemistry - ketones - nitrogen-centered radicals - cascade reactions - vicinal
diamines