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Synthesis 2017; 49(24): 5335-5338
DOI: 10.1055/s-0036-1589103
DOI: 10.1055/s-0036-1589103
psp
A Practical Gram-Scale Synthesis of Acrylohydroxamic Acid
Autoren
This work was supported by a contract from ALKYMOS, Inc. Funding for the ApexII diffractometer was provided by the National Science Foundation (MRI, CHE-0420497).
Weitere Informationen
Publikationsverlauf
Received: 15. Juli 2017
Accepted after revision: 09. August 2017
Publikationsdatum:
30. August 2017 (online)
Abstract
Acrylohydroxamic acid, which is a useful monomer for the preparation of polymeric materials, has been prepared in a straightforward, two-step synthesis from readily available starting materials. The key steps are coupling of acrylic acid with O-tetrahydropyranylhydroxyl amine to provide protection of the hydroxylamine functionality, followed by acid cleavage of the protecting group.
Key words
hydroxamic acids - acrylohydroxamic acid - chelating agents - monomers - functionalized polymers - metal chelationSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1589103.
- Supporting Information (PDF) (opens in new window)
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