Phenol Oxidative Dearomatization of Modified Nucleoside Templates: A Simple Access to the C7-Spiroannulated Octosyl Acid Framework

Published as part of the Special Topic Modern Cyclization Strategies in Synthesis

Abstract

Phenol oxidative dearomatization and cyclization has been executed successfully on nucleoside templates to synthesize C7-spiroannulated perhydrofuropyran nucleosides and C6-spiroannulated perhydrofurofuran nucleosides as novel analogues of octosyl acid and related peptidyl nucleosides.

Key words

phenol oxidative dearomatization - peptidyl glycosides - modified nucleosides - Vorbrüggen glycosylation - glucose diacetonide

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