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Synthesis 2017; 49(06): 1371-1379
DOI: 10.1055/s-0036-1588103
DOI: 10.1055/s-0036-1588103
paper
Highly Efficient Synthesis of N-Sulfonylamidines via Silver-Catalyzed or Metal-Free Thermally Promoted Denitrogenative Amination of N-Sulfonyl-1,2,3-triazoles
Authors
Further Information
Publication History
Received: 21 September 2016
Accepted after revision: 27 October 2016
Publication Date:
28 November 2016 (online)
Abstract
A highly efficient synthesis of N-sulfonylamidines from N-sulfonyl-1,2,3-triazoles and amines is reported. This transformation undergoes silver-catalyzed or metal-free thermally promoted denitrogenation of N-sulfonyl-1,2,3-triazoles to afford N-sulfonylketenimine intermediates and subsequent nucleophilic addition with amines. The amine plays dual roles as base and nucleophile.
Key words
amination - denitrogenation - N-sulfonylamidines - N-sulfonyl-1,2,3-triazoles - nucleophilic additionSupporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0036-1588103.
- Supporting Information (PDF) (opens in new window)
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