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Synthesis 2016; 48(11): 1655-1662
DOI: 10.1055/s-0035-1561606
DOI: 10.1055/s-0035-1561606
special topic
Synthesis of (–)- and (+)-Gummiferol via Asymmetric Synthesis of Glycidic Amides
Authors
Further Information
Publication History
Received: 15 February 2016
Accepted after revision: 17 March 2016
Publication Date:
18 April 2016 (online)
Abstract
An efficient synthesis of the natural product (–)-gummiferol is achieved according to a novel asymmetric methodology of epoxide formation based on a new class of chiral sulfonium salts. This new methodology allows the rapid and efficient construction of the diepoxide system contained within the natural product.
Key words
asymmetric synthesis - glycidic amides - chiral sulfonium salts - natural products - diepoxidesSupporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1561606.
- Supporting Information (PDF) (opens in new window)
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