Recent Advances in Iron-Catalyzed Csp²–Csp² Cross-Couplings

Abstract

The present review article highlights recent progress in the field of iron-catalyzed cross-coupling reactions between Csp² centers. The reaction scope of various iron-catalyzed couplings between aromatic Grignard reagents and unsaturated halides is described and some mechanistic insights are given.

1 Introduction

2 Historical Work

3 Iron-Catalyzed Homocouplings of Aryl Organometallics

4 Iron-Catalyzed sp²–sp² Cross-Couplings

4.1 Arylcopper Reagents as Nucleophiles

4.2 Arylmagnesium Reagents as Nucleophiles

4.2.1 Couplings with Alkenyl Halides

4.2.2 Couplings with Heteroaryl Halides

4.2.3 Coupling with Aryl Halides

5 Conclusion

Key words

iron - homocoupling - cross-coupling - Grignard reagent - copper reagent

• References


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