Synlett 2015; 26(02): 259-264
DOI: 10.1055/s-0034-1379612
letter
© Georg Thieme Verlag Stuttgart · New York

d-Glucosamine as a Green Ligand for Palladium-Catalyzed Cross-Coupling of Aryl and Heteroaryl Halides

Authors

  • Abadh Kishor Jha

    Department of Chemistry, Indian Institute of Technology, Hauz Khas, Delhi-110016, India   Fax: +91(11)26581102   Email: njain@chemistry.iitd.ac.in
  • Rahul Kumar Shahni

    Department of Chemistry, Indian Institute of Technology, Hauz Khas, Delhi-110016, India   Fax: +91(11)26581102   Email: njain@chemistry.iitd.ac.in
  • Nidhi Jain*

    Department of Chemistry, Indian Institute of Technology, Hauz Khas, Delhi-110016, India   Fax: +91(11)26581102   Email: njain@chemistry.iitd.ac.in
Further Information

Publication History

Received: 03 October 2014

Accepted after revision: 30 October 2014

Publication Date:
02 December 2014 (online)


Graphical Abstract

Preview

Abstract

Naturally occurring d-glucosamine works as an efficient green alternative to phosphines in palladium-catalyzed Heck coupling of aryl and heteroaryl halides. An array of trans-stilbene derivatives, aryl naphthyl alkenes, heteroaryl olefins, and β-aryl-substituted acrylates has been synthesized in short reaction times in moderate to high yields.

Supporting Information