Synthesis, Inhaltsverzeichnis Synthesis 2013; 45(8): 1039-1044DOI: 10.1055/s-0032-1318389 paper © Georg Thieme Verlag Stuttgart · New York An Efficient Synthesis of N-Cyclopropylanilines by a Smiles Rearrangement Veera Reddy Arava* R&D Laboratory, Suven Life Sciences Ltd., #18, Phase-III, IDA, Jeedimetla, Hyderabad 500055, India Fax: +91(40)23193541 eMail: reddyvenis@rediffmail.com , Sreenivasula Reddy Bandatmakuru R&D Laboratory, Suven Life Sciences Ltd., #18, Phase-III, IDA, Jeedimetla, Hyderabad 500055, India Fax: +91(40)23193541 eMail: reddyvenis@rediffmail.com › Institutsangaben Artikel empfehlen Abstract Artikel einzeln kaufen Alle Artikel dieser Rubrik Abstract Treatment of 2-chloro-N-cyclopropylacetamide with phenols gave the corresponding 2-aryloxy-N-cyclopropylacetamides, which on treatment with a base gave the corresponding N-cyclopropylanilines. Key words Key wordsrearrangements - amines - cyclopropanes Volltext Referenzen References 1a Schriewer M, Petersen U, Grohe K, Krebs A. EP 0332033, 1989 1b Palomo Nicolau C, Cabre Castellvi F, Palomo Nicolau FE, Palomo Coll AL. EP 430847, 1991 1c Domingo Coto A, López Molina I, Palomo Coll A. ES 2015442, 1990 1d Freixas Bazaco J, Martorell Coca C. ES 2050613, 1994 1e Yoshida Y, Tabuchi F, Umetsu K, Hamada Y. JP11035530, 1999 1f Somfai E. WO 9502573, 1995 2 Cui W, Loeppky RN. Tetrahedron 2001; 57: 2953 3 Hanzlik RP, Kishore V, Tullman R. J. Med. Chem. 1979; 22: 759 4 Suckling J. Angew. Chem., Int. Ed. Engl. 1988; 27: 537 5 Salaun J. Russ. J. Org. Chem. (Engl. Transl.) 1997; 33: 742 6 Macdonald TL, Zirvi K, Burka LT, Peyman P, Guengerich FP. J. Am. Chem. Soc. 1982; 104: 2050 7 Zhao Z, Mabic S, Kuttab S, Franot C, Castagnoli K, Castagnoli NJr. Bioorg. Med. Chem. 1998; 6: 2531 8 Reichelt A, Martin FS. Acc. Chem. Res. 2006; 39: 433 9 Brown HC, Fletcher RS, Johannesen RB. J. Am. Chem. Soc. 1951; 43: 212 10 Bénard S, Neuville L, Zhu J. Chem. Commun. (Cambridge) 2010; 46: 3393 11a Kang J, Kim KS. J. Chem. Soc., Chem. Commun. 1987; 897 11b Yoshida Y, Umezu K, Hamada Y, Atsumi N, Tabuchi F. Synlett 2003; 2139 12 Gillaspy ML, Lefker BA, Hada WA, Hoover DJ. Tetrahedron Lett. 1995; 36: 7399 13 Noritaka K, Kazumasa N, Atsushi S, Atsushi K, Shinichi H, Tadashi O. US 2012004315, 2012
