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Synthesis 2012; 44(12): 1874-1884
DOI: 10.1055/s-0031-1290950
DOI: 10.1055/s-0031-1290950
special topic
Synthesis of 2-Indol-3-ylbenzofulvenes through a Tandem Reaction Catalyzed by Cationic Gold(I) Complexes
Authors
Further Information
Publication History
Received: 08 March 2012
Accepted: 30 March 2012
Publication Date:
04 May 2012 (online)
Dedicated to our good friend Professor Francisco J. Fañanás on the occasion of his 60th birthday
Abstract
A new access to benzofulvenes bearing an indol-3-yl substituent at C-2 has been developed. Treatment of 3-propargylindoles possessing an additional hydroxy group at the other propargylic position with a cationic gold(I) complex triggers a tandem 1,2-indole migration/aura-iso-Nazarov cyclization/elimination sequence that takes place under mild conditions.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information (PDF)
-
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