An Effective Nitrilimine Cycloaddition
for the Synthesis of 1,3,5-Trisubstituted 1,2,4-Triazoles
from Oximes with Hydrazonoyl Hydrochlorides

Li-Ya Wang; Wen-Che Tseng; Hui-Yi Lin; Fung Fuh Wong

doi:10.1055/s-0030-1260759

LETTER

An Effective Nitrilimine Cycloaddition for the Synthesis of 1,3,5-Trisubstituted 1,2,4-Triazoles from Oximes with Hydrazonoyl Hydrochlorides

Li-Ya Wang^a, Wen-Che Tseng^b, Hui-Yi Lin^c, Fung Fuh Wong*^b
^a The Ph.D. Program for Cancer Biology and Drug Discovery, China Medical University, No. Hsueh 91, Shih Rd., Taichung, Taiwan 40402, R. O. C.
^b Graduate Institute of Pharmaceutical Chemistry, China Medical University, No. Hsueh 91, Shih Rd., Taichung, Taiwan 40402, R. O. C.
Fax: +886(4)22078083; e-Mail: ffwong@mail.cmu.edu.tw; e-Mail: wongfungfuh@yahoo.com.tw;
^c School of Pharmacy, China Medical University, No. Hsueh 91, Shih Rd. Taichung, Taiwan 40402, R. O. C.