Endokrinologie 2009

Was ist neu?

• Glukokortikoid-induzierte Osteoporose: Zoledronsäure zur Prävention und Therapie mindestens ebenso wirksam wie Risedronat; Teriparatide führt im Vergleich zu Alendronat zu einer stärkeren Zunahme der lumbalen Knochendichte.

• Gastrointestinale Tumoren: Octreotid als Depot-Präparat beim hochdifferenzierten neuroendokrinen Karzinom des „Midgut” antiproliferativ wirksam; Everolimus in Kombination mit Octreotid LAR bei fortgeschrittenen niedrig- und mittelgradig differenzierten NET effektiv.

• Primärer Hyperparathyreoidismus: Cinacalcet als erstes Kalzimimetikum für diese Indikation zugelassen.

• Nebennierenrindenkarzinom: Vorschlag einer überarbeitete Klassifikation; die konservativen Therapiemöglichkeiten sind nach wie vor unbefriedigend; neue Ansätze werden derzeit in Studien untersucht.

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