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Synthesis 2010(9): 1500-1504
DOI: 10.1055/s-0029-1218688
DOI: 10.1055/s-0029-1218688
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New YorkCopper-Mediated Homocoupling of Vinyl Dibromides to Symmetrical Diynes
Weitere Informationen
Received
7 December 2009
Publikationsdatum:
24. Februar 2010 (online)
Publikationsverlauf
Publikationsdatum:
24. Februar 2010 (online)

Abstract
1,1-Dibromoalk-1-enes were dimerized readily in the presence of copper iodide, a diamine ligand, and cesium carbonate in DMF to give symmetrical 1,3-diynes. The reaction was found to be selective and rather general, furnishing the corresponding diynes in good yields, even with complex and sensitive dibromides, and provides useful insights into the reactivity of 1,1-dibromoalk-1-enes with copper(I).
Key words
dibromoalkenes - copper catalysis - 1,3-diynes
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