Subscribe to RSS
DOI: 10.1055/s-0028-1091257
© Georg Thieme Verlag KG Stuttgart · New York
Automatische externe Defibrillatoren – Funktionsweise und Einsatz
Automatic external defibrillator – mode of operation and clinical usePublication History
eingereicht: 14.4.2008
akzeptiert: 23.7.2008
Publication Date:
07 October 2008 (online)

Zusammenfassung
In Deutschland versterben jährlich über 100 000 Personen am plötzlichen Herztod.
Trotz verschiedener Maßnahmen bleibt jedoch die Prognose des plötzlichen Herztodes schlecht. So beträgt der Anteil an Patienten zwischen 2 und 10 %, die einen plötzlichen Herztod überleben, also aus dem Krankenhaus wieder entlassen werden. Eine Untersuchung an Patienten, bei denen zum Zeitpunkt des einsetzenden plötzlichen Herztodes eine EKG-Dokumentation verfügbar war, zeigt zu 89 % Kammerflimmern oder eine ventrikuläre Tachykardie, also Herzrhythmusstörungen, die mit einem Defibrillator terminiert werden können. Für das Überleben eines Patienten mit diesen Herzrhythmusstörungen ist die Zeit bis zur Defibrillation von herausragender Bedeutung.
Vielfältige Untersuchung haben gezeigt, dass professionelles, nicht-medizinisches Personal (Polizeibeamten, Feuerwehrleute u. a.) aber auch zufällig anwesende Personen in den meisten Fällen den Patienten vor dem Rettungsdienst erreichen. Diese Beobachtung hat zu der Überlegung geführt, Defibrillatoren zu entwickeln, die tachykarde Herzrhythmusstörungen zuverlässig selbstständig erkennen und therapieren können. Diese werden automatische externe Defibrillatoren (AED) bezeichnet. Mit ihrem Einsatz ist es möglich, dass nicht-ärztliches Personal Kammerflimmern behandeln kann und dadurch die Zeit vom Beginn der Herzrhythmusstörung bis zur Terminierung signifikant gesenkt wird. In zahlreichen Studien hat sich gezeigt, dass sowohl First Responder aber auch ungeschulte Laien den AED sicher eingesetzt haben und dadurch eine Senkung der Sterblichkeit am plötzlichen Herztod erreicht werden konnte.
Summary
Every year about 100.000 persons die from sudden cardiac death (SCD) in Germany. Although many efforts have been undertaken, mortality remains high. Only 2 – 10 % of patients with out-off hospital SCD can finally be discharged from hospital after resuscitation. Observational studies show that ventricular fibrillation and ventricular tachycardia are the primary arrhythmias underlying SCD. For both arrhythmias the main determinant for survival is the time between onset and termination by defibrillation. The chance of survival declines by 10 % for every minute of delay. These findings prompted the concept of early defibrillation by first responders.
Many studies have shown that non-medical professionals, like police men, firemen or security officers, often arrive at the patient more early than emergency medical service. Thus, „smart” automated external defibrillators (AEDs), designed to identify VT/VF and prompt the user when to deliver a shock were introduced. These devices allow lay rescuers to terminate ventricular arrhythmias before the arrival of medical professionals. By this approach the time to defibrillation could be reduced and a significant reduction in mortality could be documented in selected situation.
These encouraging results initialled the installation of AED at public places like aircrafts, airports, underground stations and shopping males. Due to the success of this approach doctors are more and more confronted with questions about technical details, reliability and cost effectiveness of these devices. The present review should give an overview about the current studies and guidelines.
Schlüsselwörter
Reanimation - automatischer externer Defibrillator - AED - plötzlicher Herztod
Key words
resusciation - automatic external defibrillator - AED - sudden cardiac death
Literatur
- 1
van Alem A P, Vrenken R H, de
Vos R, Tijssen J G, Koster R W.
Use of automated
external defibrillator by first responders in out of hospital cardiac
arrest: prospective controlled trial.
BMJ.
2003;
327
1312
MissingFormLabel
- 2
American Heart Association,
International Liasion Committee on Resuscitation, ILCOR .
Guidelines
2000 for cardiopulmonary resuscitation and emergency cardiovascular
care – An international consensus on science.
Circulation.
2000;
102 (Suppl.)
1-384
MissingFormLabel
- 3
Aufderheide T, Hazinski M F, Nichol G. et al .
Community lay rescuer automated external
defibrillation programs: key state legislative components and implementation
strategies: a summary of a decade of experience for healthcare providers,
policymakers, legislators, employers, and community leaders from
the American Heart Association Emergency Cardiovascular Care Committee,
Council on Clinical Cardiology and Office of State Advocacy.
Circulation.
2006;
113
1260-1270
MissingFormLabel
- 4
Bardy G H, Lee K L, Mark D B. et al .
Home use of automated external
defibrillators for sudden cardiac arrest.
N Engl J Med.
2008;
, e-Pub
MissingFormLabel
- 5
Bayes de Luna A, Coumel P, Leclercq J F.
Ambulatory sudden cardiac death: mechanisms of production of
fatal arrhythmia on the basis of data from 157 cases.
Am
Heart J.
1989;
117
151-159
MissingFormLabel
- 6
Caffrey S L, Willoughby P J, Pepe P E, Becker L B.
Public
use of automated external defibrillators.
N Engl J Med.
2002;
347
1242-1247
MissingFormLabel
- 7
Capucci A, Aschieri D, Piepoli M F, Bardy G H, Iconomu E, Arvedi M.
Tripling survival from
sudden cardiac arrest via early defibrillation without traditional
education in cardiopulmonary resuscitation.
Circulation.
2002;
27, 106
1065-1070
MissingFormLabel
- 8 Dillon S M, Kwaku K F.
Basic mechanisms in defibrillation. In: Zipes, Jalife Cardiac Electrophysiology – From Cell to Bedside. 3rd edition. W.B. Saunders 2000MissingFormLabel - 9
Empfehlungen der Bundesärztekammer
zur Defibrillation mit automatisierten externen Defibrillatoren
(AED) durch Laien (2001).
Dtsch Ärzteblatt.
2001;
98
A1211
MissingFormLabel
- 10 Fleming S H. OSHA encourages defibrillator use to revive workers with cardiac
arrest. OSHA Trade News Release, US Department of Labor. December
17, 2001 Available at: http://www.osha.gov/media/oshnews/dec01/trade-2001.Accessed
December 17,2001
MissingFormLabel
- 11
Gliner B E, Lyster T E, Dillon S M, Bardy G H.
Transthoracic
defibrillation of swine with monophasic and biphasic waveforms.
Circulation.
1995;
92
1634-1643
MissingFormLabel
- 12
Groeneveld P W, Kwong J L, Liu Y, Rodriguez A J, Jones M P, Sanders G D, Garber A M.
Cost-effectiveness of automated
external defibrillators on airlines.
JAMA.
2001;
286
1482-1489
MissingFormLabel
- 13
Gundry J W, Comess K A, DeRook F A, Jorgenson D, Bardy G H.
Comparison of naive sixth-grade
children with trained professionals in the use of an automated external
defibrillator.
Circulation.
1999;
100
1703-1707
MissingFormLabel
- 14
Hallstrom A P, Ornato J P, Weisfeldt M. et al .
Public-access defibrillation and survival
after out-of-hospital cardiac arrest.
N Engl J Med.
2004;
351
637-646
MissingFormLabel
- 15
Hoffmann S, Krämer R, Krause-Dietering B, Andresen D.
Der
plötzliche Herztod:- Gibt es geeignete Orte für
die Installation von Defibrillatoren?.
Clin Res Cardiol.
2008;
97
(Suppl. 1)
534
MissingFormLabel
- 16
Jorgenson D B, Skarr T, Russell J K, Snyder D E, Uhrbrock K.
AED use in businesses, public facilities and homes by minimally
trained first responders.
Resuscitation.
2003;
59
225-233
MissingFormLabel
- 17
Karch S B, Graff J, Young S. et
al .
Response time and outcome for cardiac arrest in
Las Vegas casinos.
Am J Emerg Med.
1998;
16
249-253
MissingFormLabel
- 18
Kerber R E, Becker L B, Bourland J D. et al .
Automatic external defibrillators
for public access defibrillation: recommendations for specifying and
reporting arrhythmia analysis algorithm performance, incorporating
new waveforms, and enhancing safety. A statement for health professionals
from the American Heart Association Task Force on Automatic External
Defibrillation, Subcommittee on AED Safety and Efficacy.
Circulation.
1997;
95
1677-1682
MissingFormLabel
- 19
Kerber R E, Martins J B, Kienzle M G, Constantin L, Olshansky B, Hopson R, Charbonnier F.
Energy, current, and success in defibrillation
and cardioversion: clinical studies using an automated impedance-based method
of energy adjustment.
Circulation.
1988;
77
1038-1046
MissingFormLabel
- 20
Larsen M P, Eisenberg M S, Cummins R O, Hallstrom A P.
Predicting
survival from out-of-hospital cardiac arrest: a graphic model.
Ann Emerg Med.
1993;
22
1652-1658
MissingFormLabel
- 21
McInnis K, Herbert W, Herbert D, Herbert J, Ribisl P, Franklin B.
Low compliance with
national standards for cardiovascular emergency preparedness at
health clubs.
Chest.
2001;
120
283-288
MissingFormLabel
- 22
Myerburg R J.
Sudden cardiac death: exploring the limits of our knowledge.
J Cardiovasc Electrophysiol.
2001;
12
369-381
MissingFormLabel
- 23
Myerburg R J, Fenster J, Velez M, Rosenberg D, Lai S, Kurlansky P, Newton S, Knox M, Castellanos A.
Impact of community-wide police car deployment of automated
external defibrillators on survival from out-of-hospital cardiac
arrest.
Circulation.
2002;
106
1058-1064
MissingFormLabel
- 24
Nadkarni V M, Larkin G L, Peberdy M A. et al .
First documented rhythm and
clinical outcome from in-hospital cardiac arrest among children and
adults.
JAMA.
2006;
295
50-57
MissingFormLabel
- 25
Nichol G, Stiell I G, Laupacis A, Pham B, De Maio V J, Wells G A.
A cumulative
meta-analysis of the effectiveness of defibrillator-capable emergency
medical services for victims of out-of-hospital cardiac arrest.
Ann Emerg Med.
1999;
34
517-525
MissingFormLabel
- 26
Page R L, Joglar J A, Kowal R C. et al .
Use of automated external
defibrillators by a U.S. airline.
N Engl J Med.
2000;
343
1210-1216
MissingFormLabel
- 27
Peberdy M A, Kaye W, Ornato J P, Larkin G L, Nadkarni V, Mancini M E, Berg R A, Nichol G, Lane-Trultt T.
et al: Cardiopulmonary resuscitation of
adults in the hospital: A report of 14 720 cardiac arrests
from the National Registry of Cardiopulmonary Resuscitation.
Resuscitation.
2003;
58
297-308
MissingFormLabel
- 28
Priori S G, Bossaert L L, Chamberlain D A, Napolitano C, Arntz H R, Koster R W, Monsieurs K G, Capucci A, Wellens H J.
ESC-ERC recommendations for
the use of automated external defibrillators (AEDs) in Europe.
Eur Heart J.
2004;
25
437-445
MissingFormLabel
- 29
Samson R, Berg R, Bingham R.
Pediatric Advanced Life Support Task Force, International Liaison
Committee on Resuscitation. Use of automated external defibrillators
for children: an update. An advisory statement from the Pediatric
Advanced Life Support Task Force, International Liaison Committee
on Resuscitation.
Resuscitation.
2003;
57
237-243
MissingFormLabel
- 30
Schneider T, Martens P R, Paschen H. et al .
Multicenter, randomized, controlled trial
of 150-J biphasic shocks compared with 200 to 360 J monophasic shocks
in the resuscitation of out-of-hospital cardiac arrest victims.
Optimized Response to Cardiac Arrest (ORCA) Investigators.
Circulation.
2000;
102
1780-1787
MissingFormLabel
- 31
Stults K R, Brown D D, Kerber R E.
Efficacy of an automated external defibrillator
in the management of out-of-hospital cardiac arrest: validation
of the diagnostic algorithm and initial clinical experience in a rural
environment.
Circulation.
1986;
73
701-709
MissingFormLabel
- 32
Tang W, Weil M H, Sun S, Yamaguchi H, Povoas H P, Pernat A M, Bisera J.
The effects of biphasic and conventional monophasic defibrillation on
postresuscitation myocardial function.
J Am Coll Cardiol.
1999;
34
815-822
MissingFormLabel
- 33
Thompson P D.
The cardiovascular complications of vigorous physical activity.
Arch Intern Med.
1996;
156
2297-2302
MissingFormLabel
- 34
Trappe H J, Andresen D, Arntz H R, Becker H J, Werdan K.
Stellungnahme der Deutschen Gesellschaft für Kardiologie – Herz-
und Kreislaufforschung (DGK). Position paper on „automated
external defibrillation”.
Z Kardiol.
2005;
94
287-295
MissingFormLabel
- 35
Valenzuela T D, Roe D J, Cretin S, Spaite D W, Larsen M P.
Estimating effectiveness of cardiac arrest
interventions: a logistic regression survival model.
Circulation.
1997;
96
3308-3313
MissingFormLabel
- 36
Valenzuela T D, Roe D J, Nichol G, Clark L L, Spaite D W, Hardman R G.
Outcomes
of rapid defibrillation by security officers after cardiac arrest
in casinos.
N Engl J Med.
2000;
343
1206-1209
MissingFormLabel
- 37
de Vreede-Swagemakers J JM, Gorgels A PM, Dubois-Arbouw W I, van Ree J W, Daemen M JAP, Houben L GE, Wellens H JJ.
Out-of-Hospital Cardiac Arrest in the 1990 s:
A Population-Based Study in the Maastricht Area on Incidence, Characteristics
and Survival.
J Am Coll Cardiol.
1997;
30
1500-1506
MissingFormLabel
- 38
Weaver W D, Cobb L A, Copass M K, Hallstrom A P.
Ventricular
defibrillation – a comparative trial using 175-J and 320-J
shocks.
N Engl J Med.
1982;
307
1101-1106
MissingFormLabel
- 39
Zafari A M, Zarter S K, Heggen V, Wilson P, Taylor R A, Reddy K, Backscheider A G, Dudley S C Jr.
A
program encouraging early defibrillation results in improved in-hospital
resuscitation efficacy.
J Am Coll Cardiol.
2004;
44
846-852
MissingFormLabel
Priv. Doz. Dr. med. H. Wieneke
Westdeutsches Herzzentrum, Universitätsklinikum
Essen
Hufelandstr. 55
45147 Essen
Email: heinrich.wieneke@uni-essen.de