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Synlett 2025; 36(12): 1669-1678
DOI: 10.1055/a-2564-5120
DOI: 10.1055/a-2564-5120
account
Synthesis of Aryl(TMP)iodonium Salts and Their Arylation Reactions
This work has been funded in part by Portland State University, the American Chemical Society, Petroleum Research Fund (ACS PRF, DNI 54405), and the National Science Foundation (NSF CHE 1856705, 2154500, and 2247802).
This work is dedicated to all the students who have worked diligently in the lab to obtain the results summarized in this Account, and to colleagues across the globe working to advance the chemistry of aryl(TMP)iodonium salts.
Abstract
Diaryliodonium salts continue to emerge as versatile arylation reagents. This is especially true for unsymmetrical aryl(TMP)iodonium salts (TMP = 2,4,6-trimethoxyphenyl) because they undergo highly selective aryl transfer across diverse mechanistic settings. This account outlines our motivation for exploring the chemistry of aryl(TMP)iodonium salts and our efforts to develop streamlined synthetic methods to access them and the novel arylation reactions that use them.
Publikationsverlauf
Eingereicht: 28. Februar 2025
Angenommen nach Revision: 21. März 2025
Accepted Manuscript online:
21. März 2025
Artikel online veröffentlicht:
05. Mai 2025
© 2025. Thieme. All rights reserved
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