Synlett

Issue eFirst

Bao, Zhi-Peng; Wu, Xiao-Feng: Manganese- and Iron-Catalyzed Carbonylation Reactions: A Personal Account

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Wang, Linqing; Yang, Dongxu: Strategies of In Situ Generated Magnesium Catalysis in Asymmetric Reactions

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Shigehisa, Hiroki: Cyclization via Metal-Catalyzed Hydrogen Atom Transfer/Radical-Polar Crossover

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Laru, Sudip; Ghosh, Sumit; Hajra, Alakananda: C–H Functionalization of Quinoxalines

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Hu, Deqing; Jiang, Xuefeng: Perspectives for Uranyl Photoredox Catalysis

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Chatterjee, Sourav; Paul, Bishwajit; Shanker, Govindaswamy: His-Tagging: Exploring Precise Chemical Modification of Histidine-Containing Bioactive Peptide Sequences

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Shalev, Ori; Biali, Silvio E.: Ketocalixarenes: Versatile yet still Unexplored Macrocycles

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Lu, Wenjun: The Cross-Selectivity in Palladium-Catalyzed Coupling of Simple Aryl C–H Bonds

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Kong, Lingbing; Cui, Chunming: Perspective on Organoboron Chemistry

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Song, Chunlan; Liu, Kun; Dong, Xin; Chiang, Chien-Wei; Lei, Aiwen: Recent Advances in Electrochemical Oxidative Cross-Coupling for the Construction of C–S Bonds

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Aartsma-Rus, Annemieke: Applying Lessons Learned from Developing Exon Skipping for Duchenne to Developing Individualized Exon Skipping Therapy for Patients with Neurodegenerative Diseases

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Yang, Xiao-Guang; Hu, Ze-Nan; Jia, Meng-Cheng; Du, Feng-Huan; Zhang, Chi: Recent Advances and the Prospect of Hypervalent Iodine Chemistry

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Zhang, Mingyue; Zhang, Mengmeng; Li, Changsheng; Wang, Wenyang; Shi, Guohui; Luo, Shipeng; Chen, Liang-An; Dai, Qiang: Advances in the Intermolecular Asymmetric Allylic Functionalization of Unreactive Acyclic Alkenes

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Cong, Xuefeng; Zeng, Xiaoming: Chromium-Catalyzed Cross-Coupling Reactions by Selective Activation of Chemically Inert Aromatic C–O, C–N, and C–H Bonds

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Liu, Ting; Wang, Congyang: Manganese-Catalyzed C(sp²)–H Addition to Polar Unsaturated Bonds

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Rutjes, Floris P. J. T.; Bonger, Kimberly M.; Neumann, Kevin: Bioorthogonal Chemistry at Radboud University: Past, Present and Future

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Pang, Xiaobo; Shu, Xing-Zhong: Titanium: A Unique Metal for Radical Dehydroxylative Functionalization of Alcohols

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Singha, Tushar; Hari, Durga Prasad: Visible-Light-Mediated Strain-Release Radical Spirocyclizations: Access to Functionalized Spirocyclobutanes

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Li, Jiagen; Jiang, Xuefeng: Advances on the Synthesis of C-Aryl-glycosides Since 2019

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Gou, Bo-Bo; Shen, Wen-Jie; Gu, Qing; You, Shu-Li: Synthesis of Chiral Cyclopentadienyl Rhodium Complexes and Their Application in Enantioselective C–H Functionalization Reactions

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Gao, Xinyu; Ren, Keke; Ma, Lijuan; Wang, Nengzhong; Huang, Nianyu; Yao, Hui: Highly Regio-/Stereoselective Synthesis of Carbohydrates with Unsaturated Glycosyl Donors under Mild Conditions

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Issue Accepted Manuscripts

Tomohara, Keisuke; Nose, Takeru; Nambu, Hisanori: Straightforward synthesis of unnatural α,α-disubstituted α-amino acid derivatives using readily accessible building blocks

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Yang, Shuang; Fang, Xinqiang: Copper-Catalyzed Unconventional Reactivities of Propargylic Esters

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Maheswari, Mittali; Hussain, Nazar: Synthesis of Branched Sugars and Chiral Aromatic Building Blocks Derived from Glycals

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Martinez, Alice Karoline de Almeida; Mourão, Penina Sousa; Corrêa, Arlene: A Concise Account on Organocatalyzed Asymmetric Synthesis of Epoxide and Aziridine Derivatives from α,β-Unsaturated Carbonyl Compounds

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Thaker, Aanal; Patel, Shrusti; Dey, Rajdeep; Shaw, Suman; Patel, Bhumika; Bhatt, Hardik; CHAUBE, UDIT JAIPRAKASH: Advancements in mTOR Inhibitors for Non-Small Cell Lung Cancer: Mechanisms, Efficacy, and Future Perspectives

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Issue 02/2025

Kang, Wen-Jie; Zhang, Yanbin; Guo, Hao: Organophotocatalytic or Electrophotocatalytic Reduction and Functionalization Reactions with a Thioxanthone-TfOH Complex Catalyst

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Durukan, Canan; Grossmann, Tom N.: From Protein Structures to Functional Biomimetics

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Issue 01/2025

Lu, Xi; Huang, Yuyang; Yang, Yuxing; Shu, Chao: Advances in the Synthesis of Sulfur-Containing Cyclic Architectures via Insertion of SO₂

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Langer, Peter: Adventures in Coumarin Chemistry

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Issue 20/2024

Peruncheralathan, Saravanan; Ila, Hiriyakkanavar: Novel Organosulfur Building Blocks for Heterocycle Synthesis

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Brahmachari, Goutam: Photo- and Electrochemical Organic Transformations Involving Radical Pathway: A Retrospection of Our Green-Chemistry-Inspired Synthetic Endeavours

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Das, Dwaipayan; Mandal, Rahul Dev; Mukherjee, Prasun; Bhattacharya, Pranabes; Das, Asish R.: Skeletal Reorganization: Approaches towards the Synthesis of Aza-Heterocyclic Cores

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Kotha, Sambasivarao; Gupta, Naveen Kumar; Ansari, Saima; Singh, Deepshikha: Design of Molecular Diversity by Olefin Metathesis in Tandem with Other Reactions

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Mukherjee, Nirmalya: Mechanochemistry: A Resurgent Force in Chemical Synthesis

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Padmor, Manohar Shivaji; Pratihar, Sanjay: Methanol for Hydrogenation and Methylation of Carbonyls: Advances and Challenges in Homogeneous Catalysis

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Shinde, Rupali Dasharath; Patel, Upendra Kumar Brijmohan; Bhadra, Sukalyan: 3d-Metal-Catalyzed Single-Electron-Transfer-Induced Conversion of Carboxylic Acids and Their Equivalents

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Goebel, Jonas F.; Manna, Sourav; Satta, Pierpaolo; Tzouras, Nikolaos V.; Gooßen, Lukas J.: Introduction of Fluorinated Groups via Photoredox-Catalyzed C–H Functionalization of (Hetero-)Arenes

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Issue 19/2024

Sib, Anna; Derdau, Volker: Method Development and Syntheses Examples of Isotopically Labeled Compounds to Foster Operational Excellence in Pharma Industry

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Xiao, Siyu; Conte, Antonio; Cornelissen, Bart T.; Domling, Alexander; Elsinga, Philip H.: Multicomponent Reactions: A Promising Approach to Isotope Labeling

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Dey, Jyotirmoy; van Gemmeren, Manuel: Late-Stage C–H Deuteration of Organic Compounds via Ligand-Enabled Palladium-Catalyzed Hydrogen Isotope Exchange

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Sasamori, Takahiro: Small-Molecule Activation by Low-Coordinated Germanium Compounds

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Issue 18/2024

Langer, Peter: Adventures in the Chemistry of Nitro Compounds

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Zhou, Leijie; Guo, Hongchao: Acidic Hydrogen-Tethered Electron-Deficient Acceptors for Phosphine-Catalyzed Annulations

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Issue 17/2024

Gravel, Edmond; Demeese, Céline; Doris, Eric: Polydiacetylene Micelles in Nanomedicine and Beyond

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Langer, Peter: Synthesis of Heterocycles by a C–C Cross-Coupling/Alkyne-Carbonyl-Metathesis Strategy

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Issue 16/2024

Langer, Peter: Adventures in CH-Arylation Chemistry

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Tabaru, Kazuki; Obora, Yasushi: Pd-Catalyzed Oxidative Functionalization of Alkenes, Arenes, and 1,3-Dienes Using Molecular Oxygen as the Terminal Oxidant

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Issue 15/2024

Blaszczyk, Stephanie A.; Li, Xiaolei; Wen, Peng; Tang, Weiping: Stereo- and Site-Selective Acylation in Carbohydrate Synthesis

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Chun, Yuge; Luu, Khoi B.; Woerpel, K. A.: Acetal Substitution Reactions: Stereoelectronic Effects, Conformational Analysis, Reactivity vs Selectivity, and Neighboring-Group Participation

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Issue 14/2024

Song, Jin; Gong, Liu-Zhu: Lewis Base/3d Transition-Metal Cooperatively Catalyzed Asymmetric Reactions

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Sassi, Mauro; Mattiello, Sara; Fappani, Alice; Beverina, Luca: Polyconjugated Materials for Printed (Opto)Electronics: Introducing Sustainability

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Dhameliya, Tejas M.; Raghani, Neha R.; Desai, Meet S.; Chudasma, Shraddhaba J.; Virani, Kumkum D.: The Synthesis of Nitrogen- and Oxygen-Containing Heterocyclic Scaffolds Assisted by Ionic Liquids: A 2022 Literature Survey

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Dhameliya, Tejas M.; Shah, Disha D.; Shah, Aayushi C.; Shah, Tithi S.; Patel, Tanvi M.; Rana, Devalben K.; Sureja, Dipen K.; Bodiwala, Kunjan B.: Synthesis of Nitrogen- and Oxygen-Containing Heterocycles Catalysed by Metal Nanoparticles Reported in 2022

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Issue 13/2024

Cruz, Carlos M.; Campaña, Araceli G.: Nanographenes Out of Planarity

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Fuwa, Haruhiko: Total Synthesis of Marine Macrolide Natural Products by the Macrocyclization/Transannular Pyran Cyclization Strategy

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Galeote, Oriol; Kennington, Stuart C. D.; Mellado-Hidalgo, Miguel; Costa, Anna M.; Romea, Pedro; Urpí, Fèlix: Stereocontrolled Aldol-Like Reactions Involving Oxocarbenium Intermediates

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Martínez, Sebastián; Lichtenberg, Crispin: Bismuth-Centered Radical Species: Access and Applications in ­Organic Synthesis

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Issue 12/2024

Chen, David Yu-Kai: Adventures in Total Synthesis – The Next Chapter

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Hasegawa, Masashi; Mazaki, Yasuhiro: Stereogenic π-Conjugated Macrocycles: Synthesis, Structure, and Chiroptical Properties Including Circularly Polarized Luminescence

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Chiu, Kuei-Wei; Chein, Rong-Jie: Exploring the Power of Sulfur, Silicon, and Organocatalysis: Innovative Strategies for Asymmetric Synthesis and Advanced Synthetic Methodology

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Greb, Lutz: p-Block Element Catecholates: Lewis Superacidic, Constitutionally Dynamic, and Redox Active

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Issue 11/2024

Bag, S. S.; Banerjee, A.; Sinha, S.: Expansion of Genetic Alphabets: Designer Nucleobases and Their Applications

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Issue 10/2024

Miñoza, Shinje; Librando, Ivy L.; Liao, Hsuan-Hung: Ketone-Derived Pro-aromatic Reagents for Radical Group Transfer Reactions and Deconstructive Functionalizations

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Li, Ying; Feng, Kongling; Zhao, Ruinan; Zhu, Cuiju; Xu, Hao: Dearomatization of α-Unsubstituted β-Naphthols

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Issue 09/2024

Long, Peng-Wei; He, Tao; Klare, Hendrik F. T.; Oestreich, Martin: Skeletal Rearrangements Involving Cyclopropyl- and Alkene-Stabilized Silylium Ions

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Issue 08/2024

Li, Jinling; Zhao, Junjie; Loh, Teck-Peng: Photoredox-Catalyzed C(sp²)–H Bond Functionalization Reactions: A Short Account

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Johnson, Colton E.; Li, Shangyu; Arora, Ramon; Mirabi, Bijan; Lautens, Mark: Nickel-Catalyzed sp³ C–H Activation

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Li, Bing; Tyagarajan, Sriram; Dykstra, Kevin D.; Cernak, Tim; Vachal, Petr; Krska, Shane W.: Harnessing the Power of C–H Functionalization Chemistry to Accelerate Drug Discovery

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McNally, Andrew: Towards Catalytic C–H Activation Using Main Group Elements

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Issue 07/2024

Kashyap, Sauvik; Phukan, Prodeep: Bromamine-T (TsNBrNa): A Biologically Significant, Versatile Bromo-Organic Reagent

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Toshima, Kazunobu; Takahashi, Daisuke; Isozaki, Yuka: Photo-Induced Glycosylations Using Organophotoacids: A New Environmentally Benign Carbohydrate Synthesis

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Qin, Yang: Pt(II)-Bisacetylide ‘Roller Wheels’: Molecular Engineering towards Small Bandgap, High Crystallinity, and Controlled Triplet Exciton Processes

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Issue 06/2024

Wang, Zhao-Li; Liu, An-Di; Liu, Li; Cheng, Liang: Recent Advances in the Synthesis of 5-(Hetero)aryl Uracil Derivatives

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Mondal, Samir Kumar; Mahto, Birkishore; Pal, Shantanu; Chandra, Girish: Current Strategies on the Enantioselective Synthesis of Modified Nucleosides

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Hudait, Nandagopal; Sakander, Norein; Kundu, Sanchari; Rasool, Bisma; Sengupta, Jhimli; Mukherjee, Debaraj: Synthesis of Modified C-Nucleosides of Therapeutic Significant: A Succinct Account

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Issue 05/2024

Evano, Gwilherm; Theunissen, Cédric: Copper-(Photo)Catalyzed Radical Reactions with Organic Halides

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Wei, Jingjing; Liang, Shuaishuai; Jiang, Lvqi; Yi, Wenbin: Direct Fluoroalkylthiolation Based on Fluoroalkanesulfite Derivatives

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Zheng, Kuan; Zhang, Bingbing; Hong, Ran: Embracing the Imperfectness of Nature using Highly Reactive N-Acyl Azahexatrienes

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Kouklovsky, Cyrille; Poupon, Erwan; Evanno, Laurent; Vincent, Guillaume: Total Synthesis of Mavacuran Alkaloids via Bioinspired and Non-Bioinspired Strategies

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Hong, Xiaoling; Chen, Peng; Li, Huilin; She, Xuegong: Bioinspired Total Syntheses of Gymnothelignans

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Zhang, Fan; Chen, Chongchong; Hu, Xiangdong: Investigations on Biomimetic Dimerization in Natural Product Synthesis

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Gao, Yanqun; Cheng, Lu; Shi, Wei; Ouyang, Yuejun; Han, Wei: New Paradigms in Catalysis Inspired by Cytochromes P450

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Wang, Di; Zhou, Tao; Ren, Jianfeng; Hirst, Jonathan D.; Gao, Zhanghua; Tang, Bencan: Applications of Quantum Chemistry in Biomimetic Syntheses of Polycyclic Furanocembrane Derivatives

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Issue 04/2024

Nishimoto, Yoshihiro; Yasuda, Makoto: Acetate/Alkoxide/Halide Shuttle Systems Mediated by Lewis Acid Catalysts for Insertion Reaction of a One-Carbon Unit into Carbon–Carbon or Carbon–Halogen Bonds

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Kondo, Yuta; Morimoto, Hiroyuki; Ohshima, Takashi: Development of Novel Catalytic Direct Syntheses of N-Unsubstituted Ketimines and Their Applications to One-Pot Reactions

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Kim, Woo Hee; Park, Jin Hyun; Lee, Sun Bu; Israr, Muhammad; Koo, Byeong Jun; Kim, Soo Bok; Kim, Soyeon; Bae, Han Yong: Sustainable Organocatalytic Processes to Access Alkyl SuFEx Click Hubs and Tetrasubstituted Carbon Centers: Potential Libraries for Multidisciplinary Applications

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On, Ivan K. W.; Zhu, Ye: Enantioselective Palladium-Catalyzed Suzuki–Miyaura Reactions Enabled by Ionic Ligand–Substrate Interactions

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Koike, Takashi: Small Aromatics Bearing Two Diarylamino Termini: Highly Reducing Organic Photocatalysts

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Issue 03/2024

Aggarwal, Varun; Bala, Ekta; Saima, Saima; Pathan, Sameer; Guleria, Saksham; Sharma, Sakshi; Selvaraj, Manickam; Verma, Praveen Kumar: Recent Developments in Photocatalytic Reduction of Nitro Compounds to Valuable Scaffolds

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Banoun, Camille; Magnier, Emmanuel; Dagousset, Guillaume: Recent Uses of Photogenerated Oxygen-Centered Radicals in Intermolecular C–O Bond Formation

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Issue 02/2024

Čarný, Tomáš; Šebesta, Radovan: Comparison of Diastereoselective ortho-Metalations and C–H ­Activations of Chiral Ferrocenes

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Sreenivasulu, Chinnabattigalla; Kishore, Dakoju Ravi; Basuli, Suchand; Satyanarayana, Gedu: Palladium-Catalyzed Acylation Strategies and Their Applications Towards Biologically Relevant Products

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Fujihara, Tetsuaki: Borylative Difunctionalization of Unsaturated Hydrocarbons Using Borylcopper Species

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Issue 01/2024

Dahiwadkar, Rahul; Kaloo, Masood A.; Kanvah, Sriram: Functional α-Cyanostilbenes: Sensing to Imaging

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Huang, Jing; He, Long; Wang, Jiaoliang; Xu, Junchao; Yuan, Lin: Near-Infrared Hemicyanine Fluorophores with Optically Tunable Groups: A ‘Leap Forward’ for in Vivo Sensing and Imaging

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Cheng, Junfeng; Lei, Zuhai: New High-Performance Fluorescent Dye Scaffolds: Applications for Bioimaging and Biosensing

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Yu, Changjiang; Sun, Yingzhu; Jiao, Lijuan; Hao, Erhong: Recent Advances in Highly Fluorescent Hydrazine-Inserted Pyrrole-Based Diboron-Anchoring Fluorophores: Synthesis and Properties

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Yadav, Bharti; Ravikanth, Mangalampalli: Functionalized Aza-BODIPYs and Their Use in the Synthesis of Aza-BODIPY-Based Complex Systems

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Issue 20/2023

Park, Jinjae; Kim, Tae Lyn; Cheon, Cheol-Hong: Total Syntheses of 2,2′-Biindolyl Alkaloids via Cyanide-Catalyzed Imino-Stetter Reaction

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Mori, Shogo; Sakurai, Shu; Naka, Hiroshi; Saito, Susumu: Metal-Loaded Semiconductor-Photocatalysis of Alcohols for Selective Organic Synthesis: A Personal Account

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Sohail, Muhammad; Tanaka, Fujie: Synthesis of Functionalized Spirooxindole Polycycles: Use of Cyclic 1,3-Diones as Reactants or as Condition-Tuning Molecules

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Tan, Jiajing; Feng, Xiaoying; Fan, Rong; Zhuang, Zhe; Guo, Yifeng: When Aryne Chemistry Meets Organosulfur Compounds

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Issue 19/2023

Lu, Xi; Wang, Yini; Xie, Kailin; Zhang, Jian: Cross-Coupling Reactions between Alkenes by C–H Cyclometalation

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Sakamoto, Jukiya; Ishikawa, Hayato: Bioinspired Total Syntheses of Secologanin-Related Natural Products: A Demonstration of the Power of Secologanin in the Flask

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Issue 18/2023

Essman, Jake Z.; Sharma, Hayden A.; Jacobsen, Eric N.: Development of Enantioselective Lithium-Isothiourea-Boronate–Catalyzed Matteson Homologations

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Bao, Zhicheng; Wang, Jianbo: Transition-Metal-Free Insertion of Diazo Compounds, N-Arylsulfonylhydrazones or Ylides into Organoboronic Acids or Their Derivatives

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Wang, Dong; XU, Tao: Recent Advances in the Preparation and Asymmetric Transformation of α-Haloboron Compounds

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Chen, Lili; Xu, Senmiao: Ligand-Enabled Regio- and/or Stereoselective Hydroboration of Alkenes

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Gillions, Joseph P.; Elsherbeni, Salma A.; Winfrey, Laura; Yun, Lei; Melen, Rebecca L.; Morrill, Louis C.; Pulis, Alexander P.: Recent Advances in Catalysis Using Organoborane-Mediated Hydride Abstraction

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Monteiro, Sofia A. G.; Gois, Pedro M. P.; António, João P. M.: Boronic Acids and Beyond: ROS-Responsive Prodrugs as Tools for a Safer and More Effective Cancer Chemotherapy

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Issue 17/2023

Langer, Peter: Small and Smart: Adventures in Epihalohydrin Chemistry

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Sankara, Chenikkayala Siva; Gaikwad, Shweta Prakash; Namboothiri, Irishi N. N.: Synthesis of Natural Products, Carbocycles, and Heterocycles by Hauser–Kraus Annulation

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Shimajiri, Takuya; Jacquot de Rouville, Henri-Pierre; Heitz, Valérie; Akutagawa, Tomoyuki; Fukushima, Takanori; Ishigaki, Yusuke; Suzuki, Takanori: Crystal Engineering, Electron Conduction, Molecular Recognition and Reactivity by Chalcogen Bonds in Tetracyanoquinodimethanes Fused with [1,2,5]Chalcogenadiazoles

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Issue 16/2023

Dodds, Amy C.; Waddell, Lachlan J. N.; Sutherland, Andrew: Regioselective Functionalization of Arenes Using Iron Triflimide Catalysis

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Compain, Philippe: From Sweet Molecular Giants to Square Sugars and Vice Versa

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Issue 15/2023

Münzer, Lukas; Schmalz, Hans-Günther: Lessons from the Total Synthesis of Highly Substituted Benzophenone Natural Products

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Langer, Peter: Adventures in the Chemistry of 1,1-Diacylcyclopropanes

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Issue 14/2023

Chen, Yang; Chen, Weihao; Gu, Xiao; Ho, Chun-Yu: Our Voyage from Catalytic Cross-Hydroalkenylation to Transfer-Dehydroaromatization of Cyclic π-Systems: Reactivity and Selectivity Changes Enabled by NHC-Ni and NHC-Pd Hydride Equivalents

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Oliva, Monica; Chernobrovkina, Viktoriia V.; Van der Eycken, Erik V.; Sharma, Upendra Kumar: Boronic Acids and Their Derivatives as Continuous-Flow-Friendly Alkyl Radical Precursors

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Issue 13/2023

Rivas, Mónica; Gevorgyan, Vladimir: Advances in Selected Heterocyclization Methods

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Robins, Jacob G.; Johnson, Jeffrey S.: Development of New Reactions Driven by N–O Bond Cleavage: from O-Acyl Hydroxylamines to Tetrodotoxin

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Issue 12/2023

Iziumchenko, Valeriia; Gevorgyan, Vladimir: Recent Advances in Dual Triplet Ketone/Transition-Metal Catalysis

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Ren, Mi; Lu, Ming-Zhu; Loh, Teck-Peng: Catalyst-Free Reactions under Biocompatible Conditions

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Sokolova, Olga O.; Dalling, Andrew G.; Bower, John F.: C–C Bond Activations of Minimally Activated Cyclopropanes

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Pradhan, Suman; Das, Shoubhik: Recent Advances on the Carboxylations of C(sp³)–H Bonds Using CO₂ as the Carbon Source

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Gilbert, Audrey; Bach, Thorsten: The Awakening of a Sleeping Beauty: The ortho Photocycloaddition in the Total Synthesis of Protoilludane- and Prezizaene-Type ­Sesquiterpenes

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Lee, Jeonghyo; Chang, Sukbok: Versatile Utility of Cp*Co(III) Catalysts in C–H Amination under Inner- and Outer-Sphere Pathway

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Jagtap, Rahul A.; Kanai, Motomu: Sustainable and Mild Catalytic Acceptorless Dehydrogenations

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Issue 11/2023

Wang, Liu-Yang; Yang, Lan; Chen, Jie; Zhou, Ling: Chiral Phosphoric Acid Catalyzed Asymmetric Cycloadditions: from Alkenes to Alkynes

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Tong, Rongbiao: The Untold Journey of Total Synthesis of Natural Products

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Issue 10/2023

Odagi, Minami; Nagasawa, Kazuo: Total Synthesis of Fused Polycyclic Alkaloids Based on Oxidative Phenolic Couplings and Aza-Michael Reactions

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Yuan, Binbin; Oliveira, João C. A.; Ackermann, Lutz: Understanding and Describing London Dispersion Effects in ­Transition-Metal-Catalyzed C–H Activations

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Issue 09/2023

Ueda, Yohei; Tsurugi, Hayato; Mashima, Kazushi: Cobalt-Catalyzed Alkynylation of Organic Compounds: Hydroalkynylation, Dehydrogenative Alkynylation, and Reductive Alkynylation

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Sumino, Shuhei; Ryu, Ilhyong: Bromine-Radical-Mediated Bromoallylation of C–C Unsaturated Bonds: A Facile Access to 1,4-, 1,5-, 1,6-, and 1,7-Dienes and Related Compounds

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Issue 08/2023

Cai, Bin; Toh, Ren Wei; Ang, Hwee Ting; Wu, Jie; Panek, James S.: Stereo- and Regioselective Synthesis of (E,E)-Dienes: Evolution from the Transition-Metal-Catalyzed Cross-Coupling to Titanium Alkoxide-Based Alkyne–Alkyne Reductive Coupling

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Sahu, Rajesh; Kapdi, Anant R.: PTABS: A Unique Water-Soluble π-Acceptor Caged Phosphine

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Issue 07/2023

Ambegave, Shivhar B.; Patil, Nitin T.: Gold-Catalyzed Cross-Coupling and 1,2-Difunctionalization ­Reactions: A Personal Account

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Shivam, Shivam.; Chavan, Kailas A.; Chauhan, Amar N. S.; Erande, Rohan D.: Recent Advances in [3+2]-Cycloaddition-Enabled Cascade Reactions: Application to Synthesize Complex Organic Frameworks

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Sahoo, Jigyansa; Panda, Jeetendra; Sahoo, Gokarneswar: Unravelling the Development of Non-Covalent Organocatalysis in India

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Basak, Shubhajit; Paul, Tripti; Maharana, Prabhat Kumar; Debnath, Bijoy; Punniyamurthy, Tharmalingam: Transition-Metal-Catalyzed Directing-Group-Assisted C4-H Carbon–Carbon Bond Formation of Indole

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Neena, Neena; Chaudhri, Vishwas; Singh, Fateh V.; China, Hideyasu; Dohi, Toshifumi; Kumar, Ravi: Synthetic Utility of the Vilsmeier–Haack Reagent in Organic Synthesis

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PH, Krushnamurthy; KS, Subramanya; Das, Simita; G., Dhananjaya; Mahanta, Nilkamal: Recent Advancements in Bottromycin Biosynthesis

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Issue 06/2023

Parida, Keshaba N.; Moorthy, Jarugu Narasimha: Catalytic Oxidations with ortho-Substituted Modified IBXs

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Saikia, Anil K.: Synthesis of Heterocyclic Scaffolds via Prins, Oxonium-Ene and Related Cyclization Reactions

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Kotha, Sambasivarao; Ansari, Saima; Gupta, Naveen Kumar: Selectivity: A Goal for Synthetic Economy

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Singh, Ajit Kumar; Kumar, Deepak; Singh, Baghendra; Indra, Arindam: Replacing Anodic Oxygen Evolution Reaction with Organic ­Oxidation: The Importance of Metal (Oxy)Hydroxide Formation as the Active Oxidation Catalyst

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Singh, Anupam Kumar; Shinde, Rupali Dasharath; Kumar, Jogendra; Bhadra, Sukalyan: Functionalization of Alkyl Groups Adjacent to Azoles: Application to the Synthesis of α-Functionalized Carboxylic Acids

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Sunny, Steeva; Maingle, Mohit; Seth, Kapileswar: Advances in Bifunctional Squaramide-Catalyzed Asymmetric Sulfa-Michael Addition: A Decade Update

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Ranu, Brindaban C.; Adak, Laksmikanta; Mukherjee, Nirmalya; Ghosh, Tubai: Benign-Metal-Catalyzed Carbon–Carbon and Carbon–Hetero­atom Bond Formation

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Issue 05/2023

Kretzschmar, Martin; Gulder, Tanja: Discovering the Site-Selective Umpolung of Ketones Triggered by Hypervalent Fluoro-Iodanes – Why Investigating Side Reactions Matters!

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Langer, Peter: Adventures in 1,1-Diphenylacetone Dianion Chemistry

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Issue 04/2023

Streuff, Jan: Reductive Umpolung and Defunctionalization Reactions through Higher-Order Titanium(III) Catalysis

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Xu, Jing: Total Synthesis of the Caged Diterpenoid Atropurpuran

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Issue 03/2023

Wei, Kua-Fei; Jiang, Xiao-Lei; Ru, Guang-Xin; Zhu, Xiu-Hong; Shen, Wen-Bo: Recent Progress towards the Transition-Metal-Catalyzed Dearomatizing Spirocyclization Reactions of Indolyl Ynones

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Zard, Samir Z.: Meanderings of a Curious Chemist

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Issue 02/2023

Zhou, Han; Liu, Yin-Ling; Tang, Shi: Recent Advances on Radical-Mediated Cyanoalkylation/Cyanation using AIBN and Analogues as the Radical Sources

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Issue 01/2023

Hilt, Gerhard: A Twenty-Year Survey in Low-Valent Cobalt-Catalyzed Transformations Comes to an End – A Farewell

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Cao, Jin; Zhu, Shou-Fei: Chiral Proton-Transfer Shuttle Catalysts Promoted Enantio­selective Nazarov Cyclization

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Issue 20/2022

Tan, Shen; Chen, Qi; Lan, Ping; Banwell, Martin G.: Troponoid Compounds as Therapeutic Agents and as Targets and Templates for Chemical Synthesis

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Xiang, Shao-Hua; Cheng, Jun Kee; Tan, Bin: The Application of 2-Naphthols in Asymmetric Synthesis of Atropisomers

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Issue 19/2022

Yudin, Andrei K.: Synthetic Tools that Enable Synthesis and Understanding of Bioactive Macrocycles

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Driver, Tom G.: Unlocking Electrophilic N-Aryl Intermediates from Aryl Azides, Nitroarenes, and Aryl Amines in Cyclization–Migration Reactions

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Issue 18/2022

Liu, Wei; Wang, Donglei; Zhang, Dekun; Yang, Xiaoyu: Catalytic Kinetic Resolution and Desymmetrization of Amines

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Issue 17/2022

Taylor, Scott D.: A Decade of Research on Daptomycin

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Langer, Peter: Synthesis of Nitrogen Heterocycles by a C–C Cross-Coupling/Cycloisomerization Strategy

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Issue 16/2022

Langer, Peter: Synthesis of Nitrogen Heterocycles by Domino C–N Coupling/Hydroamination Reactions

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Yu, Zhen; Wang, Li; Liu, Li; Wang, Meng; Yang, Hong: No Sacrifice No Gain: Construction of Cleavable Bridged Macrobicyclic Olefins for Precision Polymers

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Issue 15/2022

Lu, Chao; Chen, Xi: Flexible Piezoionic Strain Sensors toward Artificial Intelligence Applications

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Hirao, Toshikazu; Amaya, Toru: Transformations of Main-Group Organometallics Induced by Transition Metals

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Issue 13/2022

Langer, Peter: Palladium-Catalyzed Synthesis of Heterocyclic Ring Systems by Combination of Regioselective C–C with Twofold C–N Couplings

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Hajinasiri, Rahimeh: Acetylenic Esters in Organic Synthesis

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Issue 12/2022

Lücke, Daniel; Kalesse, Markus: Chiral Polyoxygenated Tertiary Alcohols through Kiyooka Aldol Reaction

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Kandappa, Sunil Kumar; Ahuja, Sapna; Singathi, Ravichandranath; Valloli, Lakshmy Kannadi; Baburaj, Sruthy; Parthiban, Jayachandran; Sivaguru, Jayaraman: Using Restricted Bond Rotations to Enforce Excited-State Behavior of Organic Molecules

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Issue 11/2022

Wei, Yunlong; Wu, Xinxin; Zhu, Chen: Radical Heteroarylation of Alkenes and Alkanes via Heteroaryl ­Migration

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Langer, Peter: Cross-Coupling Reactions of Polyhalogenated Heterocycles

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Issue 10/2022

Bennett, Clay S.: Evolution of a Reagent-Controlled Strategy for β-Selective C-Glycoside Synthesis

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Tian, Bing; Chen, Pinhong; Liu, Guosheng: Palladium-Catalyzed Intermolecular Carbonylation-Based Difunctionalization of Alkenes

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Tom, Mai-Jan; Evans, P. Andrew: Asymmetric Rhodium-Catalyzed Allylic Substitution Reactions with Nitrile-Stabilized Carbanions

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Issue 09/2022

Ghashghaei, Ouldouz; Rodríguez, Pau Nadal; Lavilla, Rodolfo: Development of Heterocyclic Multicomponent Reactions through Guided Exploration: Direct, Reasonable and Unpredictable Processes

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Liu, Jingchun; Xi, Shuang; Tang, Yefeng: Biomimetic Diels–Alder Reactions in Natural Product Synthesis: A Personal Retrospect

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O’Neill, Robert T.; Boulatov, Roman: The Contributions of Model Studies for Fundamental Understanding of Polymer Mechanochemistry

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Issue 08/2022

Wan, Caiwen; Shi, Jiarong; Li, Yang: Reactions of Sulfoxides with Benzynes

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Langer, Peter: Adventures in 1,3-Selenazole Chemistry

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Esser, Birgit; Wössner, Jan S.; Hermann, Mathias: Conjugated Nanohoops with Dibenzo[a,e]pentalenes as Nonalternant and Antiaromatic π-Systems

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Issue 07/2022

Laali, Kenneth K.; Kalkhambkar, Rajesh G.; Sutar, Suraj M.: Recent Advances in the Synthesis of Diverse Libraries of Small-Molecule Building Blocks in Ionic Liquids (ILs)

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Wørmer, Gustav J.; Poulsen, Thomas B.: The [4.3.0] Piperidine Alkaloids: Architectures, Biology, Biosyntheses, and the Complete Details of the Asymmetric Syntheses of Streptazone A and Abikoviromycin

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Issue 06/2022

Sekiya, Ryo; Harada, Kentaro; Nitta, Natsumi; Haino, Takeharu: Resorcinarene-Based Supramolecular Capsules: Supramolecular Functions and Applications

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Shindo, Mitsuru; Iwata, Takayuki: Cycloaddition Initiated by Ynolates: High-Energy Dianion Equivalents as a Molecular Glue

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Issue 05/2022

Bols, Mikael; Frihed, Tobias Gylling; Pedersen, Martin Jæger; Pedersen, Christian Marcus: Silylated Sugars – Synthesis and Properties

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Ohmori, Ken; Suzuki, Keisuke: Group-Selective Approaches to Complex Natural Product Synthesis: Three Examples of Diastereotopos-Selective Reactions

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Langer, Peter: Synthesis of Purines and Related Molecules by Cyclization ­Reactions of Heterocyclic Enamines

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Issue 04/2022

Kiss, Loránd; Ouchakour, Lamiaa; Nonn, Melinda; Remete, Attila M.: Application of Oxidative Ring Opening/Ring Closing by Reductive Amination Protocol for the Stereocontrolled Synthesis of Functionalized Azaheterocycles

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Berger, Florian; Ritter, Tobias: Site-Selective Late-Stage C–H Functionalization via Thianthrenium Salts

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Issue 03/2022

Langer, Peter: Domino Reactions of Chromones with Heterocyclic Enamines

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He, Yuli; Tao, Ran; Zhu, Shaolin: Nickel Hydride Catalyzed Remote Hydroarylation of Olefins

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Hafezi, Nema; Mascal, Mark: Chemistry of the Heterotriquinanes and Heterotriquinacenes

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Issue 02/2022

Mateos, Javier; Cuadros, Sara; Vega-Peñaloza, Alberto; Dell’Amico, Luca: Unlocking the Synthetic Potential of Light-Excited Aryl Ketones: Applications in Direct Photochemistry and Photoredox Catalysis

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Cauwenbergh, Robin; Das, Shoubhik: Photocatalysis: A Green Tool for Redox Reactions

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Issue 01/2022

Rugen, Christian J.; Alcarazo, Manuel: α-Cationic Phosphines: from Curiosities to Powerful Ancillary Ligands

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Li, Xuechen: Long Journey on Daptomycin

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Issue 20/2021

Carreiras, Maria do Carmo; Marco-Contelles, José: Five-Membered-Ring-Fused Tacrines as Anti-Alzheimer’s Disease Agents

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Crusats, Joaquim; Moyano, Albert: Absolute Asymmetric Catalysis, from Concept to Experiment: A Narrative

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Langer, Peter: Synthesis and Reactions of 1,3,5-Tri- and 1,3,5,7-Tetracarbonyl Compounds

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Issue 19/2021

Kumar, Vinod: Designed Synthesis of Diversely Substituted Hydantoins and Hydantoin-Based Hybrid Molecules: A Personal Account

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Benke, Zsanett; Nonn, Melinda; Remete, Attila M.; Fustero, Santos; Kiss, Loránd: Diversity-Oriented Synthesis of Highly Functionalized Alicycles across Dipolar Cycloaddition/Metathesis Reaction

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Issue 18/2021

Iqbal, Shoaib; Sharif, Muhammad; Langer, Peter: Suzuki–Miyaura Coupling Reactions of Fluorohalobenzenes

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Zhong, Zhuliang; Lyu, Mao-Yun; Ma, Hao-Ran; Wong, Henry N. C.; Peng, Xiao-Shui: Pivotal Reactions in the Creation of the Polycyclic Skeleton of Cryptotrione

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Goetzke, F. Wieland; Fletcher, Stephen P.: Additions to Racemates: A Strategy for Developing Asymmetric Cross-Coupling Reactions

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Issue 17/2021

Schulz, Stefan; Poth, Dennis; Peram, Pardha Saradhi; Hötling, Susann; Menke, Markus; Melnik, Kristina; Röpke, René: Chemical Diversity of Volatile Macrocylic Lactones from Frogs

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Shear, Trevor A.; Johnson, Darren W.: Main Group Supramolecular Chemistry Led to Surprising New Directions in the Self-Assembly of Organic Macrocycles, Cages, and Cyclophanes

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Issue 16/2021

Lipshutz, Bruce H.: Illuminating a Path4914. Copyright 2016 Wiley for Organic Synthesis Towards Sustainability. No One Said It Would Be Easy…

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Issue 14/2021

Romero-Ibañez, Julio; Fuentes, Lilia; Sartillo-Piscil, Fernando: Transition-Metal-Free Functionalization of Saturated and Unsaturated Amines to Bioactive Alkaloids Mediated by Sodium Chlorite

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Rubtsov, Aleksandr E.; Malkov, Andrei V.: Developing a Methodology for Catalytic Asymmetric Crotylation of Aldehydes

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Floreancig, Paul E.: Perrhenate Esters as Intermediates in Molecular Complexity-Increasing Reactions

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Tong, Shuo; Wang, Mei-Xiang: Domino Reactions of Tertiary Enamides in Organic Synthesis

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Issue 12/2021

Sanford, Amberly B.; Jarvo, Elizabeth R.: Harnessing C–O Bonds in Stereoselective Cross-Coupling and Cross-Electrophile Coupling Reactions

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Tucker, Zachary D.; Ashfeld, Brandon L.: (4+1)-Cycloadditions Exploiting the Biphilicity of Oxyphosphonium Enolates and Rh^II/Pd^II-Stabilized Metallocarbenes for the Construction of Five-Membered Frameworks

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Issue 11/2021

Lübcke, Marvin; Szabó, Kálmán J.: Diazocarbonyl Compounds in Organofluorine Chemistry

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Kuzuhara, Daiki; Yamada, Hiroko: Porphyrinoids with Vinylene Bridges

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Issue 10/2021

Chen, Wufeng; Li, Jianfeng; Cui, Chunming: Rare-Earth-Catalyzed Hydrosilylation and Dehydrogenative Coupling of Hydrosilanes

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Scholtes, Jan Felix; Trapp, Oliver: Asymmetric Induction and Amplification in Stereodynamic Catalytic Systems by Noncovalent Interactions

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Issue 09/2021

Fleurisson, Claire; Benedetti, Erica; Micouin, Laurent: Cyclic cis-1,3-Diamines Derived from Bicyclic Hydrazines: Synthesis and Applications

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Glueck, David S.: Catalytic Asymmetric Synthesis of P-Stereogenic Phosphines: Beyond Precious Metals

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van Gemmeren, Manuel; List, Benjamin: How and Why Crowd Reviewing Works

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Issue 08/2021

Rodríguez, Manuel R.; Díaz-Requejo, M. Mar; Pérez, Pedro J.: Development of Molecular Complexity through Nitrene-Transfer Reactions Catalyzed by Copper and Silver Scorpionate Complexes

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Renata, Hans: Exploration of Iron- and α-Ketoglutarate-Dependent Dioxygenases as Practical Biocatalysts in Natural Product Synthesis

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Issue 07/2021

Campillo-Alvarado, Gonzalo; MacGillivray, Leonard R.: Opportunities Using Boron to Direct Reactivity in the Organic Solid State

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Tan, Dong-Xing; Han, Fu-She: Synthetic Studies towards the Total Synthesis of Indole Alkaloids Containing Indolyl Lactam Frameworks

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Issue 06/2021

Ielo, Laura; Pillari, Veronica; Miele, Margherita; Castiglione, Davide; Pace, Vittorio: Carbenoid-Mediated Homologation Tactics for Assembling (Fluorinated) Epoxides and Aziridines

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Orian, Laura; Bickelhaupt, F. Matthias: Designing Rh(I)-Half-Sandwich Catalysts for Alkyne [2+2+2] Cycloadditions

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Taniguchi, Tsuyoshi: Strategy for the Use of Molecular Oxygen in Organic Synthesis

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Issue 05/2021

Berthold, Dino; Breit, Bernhard: Total Syntheses of Cylindrocyclophanes Exemplifying the Power of Transition-Metal Catalysis in Natural-Product Synthesis

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Gansäuer, Andreas: From Enantioselective to Regiodivergent Epoxide Opening and Radical Arylation – Useful or Just Interesting?

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Beaver, Matthew G.; Caille, Seb; Farrell, Robert P.; Rötheli, Andreas R.; Smith, Austin G.; Tedrow, Jason S.; Thiel, Oliver R.: Building Complexity and Achieving Selectivity through Catalysis – Case Studies from the Pharmaceutical Pipeline

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Nicolai, Stefano; Orcel, Ugo; Muriel, Bastian; Greenwood, Phillip D. G.; Buzzetti, Luca; Puriņš, Mikus; Waser, Jerome: Palladium-Catalyzed Functionalization of Olefins and Alkynes: From Oxyalkynylation to Tethered Dynamic Kinetic Asymmetric Transformations (DYKAT)

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Issue 04/2021

Liu, Dan; Zhang, Jing; Chen, Yiyun: Investigations on the 1,2-Hydrogen Atom Transfer Reactivity of Alkoxyl Radicals under Visible-Light-Induced Reaction Conditions

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Issue 03/2021

Solinski, Amy E.; Wuest, William M.: Collaboration in Natural Product Total Synthesis: Carolacton – A Decade of Discovery

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Wang, Hai-Xu; Wu, Kai; Che, Chi-Ming: Metal-Quinoid Carbene Chemistry: From Bonding to C–H Activation Catalysis

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Nechmad, Noy B.; Lemcoff, N. Gabriel: Sulfur-Chelated Ruthenium Olefin Metathesis Catalysts

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Issue 02/2021

Huang, Yangjie; Zhang, Mengjia; Lin, Qi; Weng, Zhiqiang: [(bpy)CuSCF₃]: A Practical and Efficient Reagent for the Construction of C–SCF₃ Bonds

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Deimling, Max; Zens, Anna; Park, Natja; Hess, Christine; Klenk, Simon; Dilruba, Zarfishan; Baro, Angelika; Laschat, Sabine: Adventures and Detours in the Synthesis of Hydropentalenes

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Issue 01/2021

Yamashita, Yasuhiro; Kobayashi, Shū: New Dimensions of Brønsted Base Catalyzed Carbon–Carbon Bond-Forming Reactions

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Wang, Nai-Xing; Zhang, Lei-Yang; Wu, Yue-Hua; Xing, Yalan: C(sp³)–H Bond Functionalization of Alcohols, Ketones, Nitriles, Ethers and Amides using tert-Butyl Hydroperoxide as a Radical Initiator

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Vine, Logan E.; Zerull, Emily E.; Schomaker, Jennifer M.: Taming Nitrene Reactivity with Silver Catalysts

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Issue 20/2020

Yokoshima, Satoshi: Synthesis of Polycyclic Natural Products through Skeletal Rearrangement

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Kotha, Sambasivarao; Tangella, Yellaiah: Modular Approaches to Cyclopentanoids and their Heteroanalogs

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Issue 19/2020

Bard, Jeremy P.; Johnson, Darren W.; Haley, Michael M.: Bumpy Roads Lead to Beautiful Places: The Twists and Turns in Developing a New Class of PN-Heterocycles

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Issue 18/2020

Talavera, María; Braun, Thomas: Rhodium(I) Complexes as Useful Tools for the Activation of Fluoroolefins

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Abou-Hamdan, Hussein; Kouklovsky, Cyrille; Vincent, Guillaume: Dearomatization Reactions of Indoles to Access 3D Indoline Structures

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Issue 17/2020

Chiba, Yusuke; Nakamura, Takashi; Matsuoka, Ryota; Nabeshima, Tatsuya: Synthesis and Functions of Oligomeric and Multidentate Dipyrrin Derivatives and their Complexes

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Huang, Pei-Qiang: Procedure-Economical, Enantioselective Total Syntheses of Polycyclic Natural Products and Analogues Containing a 3a-Hydroxyhexahydropyrrolo[2,3-b]indole-2-carboxylic Acid Residue

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Issue 16/2020

Almohseni, Hasanain A. A.; Hodgson, David M.: Evolution of a Cycloaddition–Rearrangement Approach to the Squalestatins: A Quarter-Century Odyssey

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Suresh, Kuthuru; López-Mejías, Vilmalí; Roy, Saikat; Camacho, Daniel F.; Matzger, Adam J.: Leveraging Framework Instability: A Journey from Energy Storage to Drug Delivery

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Issue 15/2020

Hooley, Richard J.: No, Not That Way, the Other Way: Creating Active Sites in Self-Assembled Host Molecules

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Wang, Yujie; Liu, Qiang: Manganese-Catalyzed Dehydrogenative/Deoxygenative Coupling of Alcohols

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Issue 14/2020

Pietrasiak, Ewa; Lee, Eunsung: Activation of C–F, Si–F, and S–F Bonds by N-Heterocyclic Carbenes and Their Isoelectronic Analogues

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Dondoni, Alessandro: Selected Research Topics of the Dondoni Group over the Last Two Decades (2000–2020)

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Issue 13/2020

Watson, Allan J. B.: The Problem with Problems: Fundamental to Applied Research Using Palladium

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Mori, Tadashi: Relevance of the Entropy Factor in Stereoselectivity Control of Asymmetric Photoreactions

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Issue 12/2020

Peng, Jingying; Thomas, Stephen P.: Activation Strategies for Earth-Abundant Metal Catalysis

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Padín, Damián; Varela, Jesús A.; Saá, Carlos: Recent Advances in Ruthenium-Catalyzed Carbene/Alkyne Metathesis (CAM) Transformations

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Issue 11/2020

Feng, Jiyao; Zhang, Zhen; Li, Xuefeng; Zhang, Zhenhua: Palladium-Catalyzed Carbonylation of Azides and Mechanistic Studies

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Li, Dongxu; Shao, Xiangfeng: Chemistry of Hetera-buckybowl Trichalcogenasumanenes

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Issue 10/2020

Deb, Titas; Franzini, Raphael M.: The Unique Bioorthogonal Chemistry of Isonitriles

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Christoffers, Jens; Wickleder, Mathias S.: Synthesis of Aromatic and Aliphatic Di-, Tri-, and Tetrasulfonic Acids

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Issue 09/2020

Shaw, Jared T.: C–H Insertion Reactions of Donor/Donor Carbenes: Inception, Investigation, and Insights

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Kiyokawa, Kensuke; Minakata, Satoshi: Iodine-Based Reagents in Oxidative Amination and Oxygenation

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Issue 08/2020

Ghorai, Sourav; Lee, Daesung: Aryne-Based Multicomponent Coupling Reactions

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Kobayashi, Yusuke; Takemoto, Yoshiji: Reactions Catalyzed by 2-Halogenated Azolium Salts: From Halogen-Bond Donors to Brønsted-Acidic Salts

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Issue 07/2020

Kadokawa, Jun-ichi: Synthesis of Amylosic Supramolecular Materials by Glucan Phosphorylase-Catalyzed Enzymatic Polymerization According to the Vine-Twining Approach

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Freeman, Jared L.; Li, Freda F.; Furkert, Daniel P.; Brimble, Margaret A.: Synthetic Studies Towards Spirocyclic Imine Marine Toxins Using N-Acyl Iminium Ions as Dienophiles in Diels–Alder Reactions

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Issue 06/2020

Sohtome, Yoshihiro; Sodeoka, Mikiko: Multiselective Catalytic Asymmetric Reactions Using α-Keto Esters as Pronucleophiles

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Rossi, Sergio; Benincori, Tiziana; Raimondi, Laura Maria; Benaglia, Maurizio: 3,3′-Bithiophene-Based Chiral Bisphosphine Oxides as Organocatalysts in Silicon-Derived Lewis Acid Mediated Reactions

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Issue 05/2020

Fernandes, Rodney A.; Kumari, Anupama; Pathare, Ramdas S.: A Decade with Dötz Benzannulation in the Synthesis of Natural Products

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Takao, Ken-ichi; Ogura, Akihiro; Yoshida, Keisuke; Simizu, Siro: Total Synthesis of Natural Products Using Intramolecular Nozaki–Hiyama–Takai–Kishi Reactions

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Issue 04/2020

Yusubov, Mekhman S.; Postnikov, Pavel; Yoshimura, Akira; Zhdankin, Viktor V.: Benziodoxole-Derived Organosulfonates: The Strongest Hypervalent Iodine Electrophiles and Oxidants

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Clementson, Sebastian; Jessing, Mikkel; Vital, Paulo J.; Kristensen, Jesper L.: Development of a Divergent Route to Erythrina Alkaloids

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Issue 03/2020

Zeng, Xiaoming: Recent Advances in Chromium-Catalyzed Organic Transformations

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Liu, Junzhi; Feng, Xinliang: Bottom-Up Synthesis of Nitrogen-Doped Polycyclic Aromatic Hydrocarbons

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Issue 02/2020

Leon, Noel J.; Yu, Hsien-Cheng; Mazzacano, Thomas J.; Mankad, Neal P.: Pursuit of C–H Borylation Reactions with Non-Precious Heterobimetallic Catalysts: Hypothesis-Driven Variations on a Design Theme

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Stephens, Thomas C.; Unsworth, William P.: Consecutive Ring-Expansion Reactions for the Iterative Assembly of Medium-Sized Rings and Macrocycles

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Issue 01/2020

Witzig, Reto M.; Sparr, Christof: Synthesis of Enantioenriched Tetra-ortho-3,3′-substituted Biaryls by Small-Molecule-Catalyzed Noncanonical Polyketide Cyclizations

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Li, Li; Wei, Yun-Long; Xu, Li-Wen: Organosilicon-Mediated Organic Synthesis (SiMOS): A Personal Account

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Issue 20/2019

Walker, Johannes C. L.; Oestreich, Martin: Ionic Transfer Reactions with Cyclohexadiene-Based Surrogates

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Coates, Greg; Rekhroukh, Feriel; Crimmin, Mark R.: Breaking Carbon–Fluorine Bonds with Main Group Nucleophiles

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Issue 19/2019

Xiao, Yan; Hu, Weiming; Sun, Song; Yu, Jin-Tao; Cheng, Jiang: Recent Advances in the Synthesis of Acridines and Phenazines

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Niquille, David L.; Hansen, Douglas A.; Hilvert, Donald: Reprogramming Nonribosomal Peptide Synthesis by Surgical Mutation

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Issue 18/2019

Tan, Tong-De; Chen, Yang-Bo; Fan, Xin-Yang; Ye, Long-Wu: Recent Progress in the Copper-Catalyzed Cascade Cyclization Involving Intramolecular Hydroamination of Terminal Alkynes

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Xiao, Yan; Sun, Song; Yu, Jin-Tao; Cheng, Jiang: Recent Advances in the Synthesis of Thiadiazoles

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Kilbinger, Andreas F. M.: Functional End Groups in Living Ring-Opening Metathesis Polymerization

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Issue 17/2019

Li, Zhen; Li, Xin; Cheng, Jin-Pei: Recent Progress in Equilibrium Acidity Studies of Organocatalysts

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Issue 16/2019

Weinreb, Steven M.: Nitrosoalkenes: Underappreciated Reactive Intermediates for Formation of Carbon–Carbon Bonds

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Mai, Juri; Ott, Sascha: The Fascinating World of Phosphanylphosphonates: From Acetylenic Phosphaalkenes to Reductive Aldehyde Couplings

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Issue 15/2019

Bakhtiari, Atefeh; Safaei-Ghomi, Javad: Effects of Chiral Ligands on the Asymmetric Carbonyl-Ene Reaction

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Ghadwal, Rajendra S.: Stable Carbon-Centered Radicals Based on N-Heterocyclic Carbenes

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Issue 14/2019

Arisawa, Mieko; Yamaguchi, Masahiko: Rhodium-Catalyzed Synthesis of Organosulfur Compounds using Sulfur

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Lacharity, Jacob J.; Zakarian, Armen: Evolution of a Chemical Strategy Toward the Synthesis of Unsymmetrically Oxidized Nuphar Alkaloids

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Issue 13/2019

Li, Chao-Jun; Huang, Jianlin; Dai, Xi-Jie; Wang, Haining; Chen, Ning; Wei, Wei; Zeng, Huiying; Tang, Jianting; Li, Chenchen; Zhu, Dianhu; Lv, Leiyang: An Old Dog with New Tricks: Enjoin Wolff–Kishner Reduction for Alcohol Deoxygenation and C–C Bond Formations

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Zhou, Zhe; Kürti, László: Electrophilic Amination: An Update

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Issue 12/2019

Yoshino, Tatsuhiko; Matsunaga, Shigeki: Cp*Co^III-Catalyzed C–H Functionalization and Asymmetric Reactions Using External Chiral Sources

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Giannis, Athanassios; Mousavizadeh, Farnoush: On Artemisinin, Cyclopamine, D-Isocitric acid, Hyperforin, Epigenetics, Sialic Acid, and More

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Issue 11/2019

Schitter, Theresa; Reding, Andreas; Werz, Daniel B.: Cascades Involving anti-Carbopalladation Steps: From Our Initial Hypothesis to Natural Product Synthesis

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Servatius, Phil; Junk, Lukas; Kazmaier, Uli: Peptide Modifications: Versatile Tools in Peptide and Natural Product Syntheses

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Issue 10/2019

Hu, Ben-Lin; Baumgarten, Martin: Thiadiazoloquinoxalines

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Kamitanaka, Tohru; Morimoto, Koji; Dohi, Toshifumi; Kita, Yasuyuki: Controlled-Coupling of Quinone Monoacetals by New Activation Methods: Regioselective Synthesis of Phenol-Derived Compounds

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Issue 09/2019

Kiraly, Peter; Morris, Gareth A.; Quanxiu, Liu; Nilsson, Mathias: Sharpening Up Your Spectra: Broadband Homonuclear Decoupling in HSQC by Real-Time Pure Shift Acquisition

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Liu, Xiang; Huang, Yu; Meng, Xu; Li, Jihui; Wang, Dong; Chen, Yongxin; Tang, Dong; Chen, Baohua: Recent Developments in the Synthesis of Nitrogen-Containing Heterocycles through C–H/N–H Bond Functionalizations and Oxidative Cyclization

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Mathew, Thomas; Gurung, Laxman; Roshandel, Sahar; Munoz, Socrates B.; Prakash, G. K. Surya: Halotrimethylsilane-Nitrite/Nitrate Salts: Efficient and Versatile Reagent System for Diverse Organic Synthetic Transformations

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Issue 08/2019

Tang, Jie; Chen, Dan; Zhang, Gen; Yang, Hongwei; Cheng, Guangbin: A “Green” Primary Explosive: Design, Synthesis, and Testing

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Martinez-Cuezva, Alberto; Lopez-Leonardo, Carmen; Alajarin, Mateo; Berna, Jose: Stereocontrol in the Synthesis of β-Lactams Arising from the Interlocked Structure of Benzylfumaramide-Based Hydrogen-Bonded [2]Rotaxanes

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Issue 07/2019

Zhang, Yuebao; Lu, Ji; Li, Hongze; Sun, Xianwei; Gao, Lu; Song, Zhenlei: Total Synthesis of Bryostatin 8 and (–)-Exiguolide: Applications of an Organosilane Strategy

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Brewster, James T.; Anguera, Gonzalo; Sessler, Jonathan L.: Expanding the Porphycene Core: Modification and Metalation

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Issue 06/2019

Canesi, Sylvain: Rapid Formation of Advanced Scaffolds from Phenols and Anilines

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Hassan, Zahid; Langer, Peter: Synthesis of Chlorinated Arenes and Hetarenes by One-Pot Cyclizations of 1,3-Bis-silyl Enol Ethers

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Lim, Hee Nam; Xing, Dong; Dong, Guangbin: Transition-Metal-Catalyzed Ketone α-Alkylation and Alkenylation with Simple Alkenes and Alkynes through a Dual Activation Strategy

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Zhou, Bo; Lu, Ailan; Zhang, Yanghui: Pd-Catalyzed C–H Silylation Reactions with Disilanes

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Issue 05/2019

Harmata, Michael: Fun with (4+3)-Cycloadditions

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Wang, Kang; Wang, Jianbo: Transition-Metal-Catalyzed Cross-Coupling with Non-Diazo Carbene Precursors

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Issue 04/2019

Xiao, Li-Jun; Ye, Meng-Chun; Zhou, Qi-Lin: Nickel-Catalyzed Highly Atom-Economical C–C Coupling Reactions with π Components

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Kato, Kenta; Segawa, Yasutomo; Itami, Kenichiro: Symmetric Multiple Carbohelicenes

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Issue 03/2019

Kräutler, Bernhard: Chlorophyll Breakdown – How Chemistry Has Helped to Decipher a Striking Biological Enigma

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Schulz, Lara; Waldvogel, Siegfried R.: Solvent Control in Electro-Organic Synthesis

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Issue 02/2019

Zhao, Kun; Ding, Linlin; Gu, Zhenhua: Development of New Electrophiles in Palladium/Norbornene-Catalyzed ortho-Functionalization of Aryl Halides

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Åkerbladh, Linda; Odell, Luke R.; Larhed, Mats: Palladium-Catalyzed Molybdenum Hexacarbonyl-Mediated Gas-Free Carbonylative Reactions

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Issue 01/2019

Wu, Xiaopeng; Sun, Song; Yu, Jin-Tao; Cheng, Jiang: Recent Applications of α-Carbonyl Sulfoxonium Ylides in Rhodium- and Iridium-Catalyzed C–H Functionalizations

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Cocq, Kévin; Barthes, Cécile; Rives, Arnaud; Maraval, Valérie; Chauvin, Remi: Synthesis of Functional Carbo-benzenes with Functional Properties: The C₂ Tether Key

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Issue 20/2018

Karanam, Praneeth; Reddy, Ganapuram Madhusudhan; Lin, Wenwei: Strategic Exploitation of the Wittig Reaction: Facile Synthesis of Heteroaromatics and Multifunctional Olefins

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Cai, Xinpei; Bai, Yu; Dai, Mingji: Total Syntheses of Spinosyn A

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Issue 19/2018

Han, Xiuling; Lu, Xiyan: Palladium(II)-Catalyzed Redox-Neutral Cyclizations of Alkynes Containing Alkenyl or Electrophilic Functional Groups: A Convenient Synthesis of Carbocycles and Heterocycles

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Shockley, Samantha E.; Hethcox, J. Caleb; Stoltz, Brian M.: Intermolecular Stereoselective Iridium-Catalyzed Allylic Alkylation: An Evolutionary Account

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Issue 18/2018

Kotha, Sambasivarao; Lahiri, Kakali; Sreevani, Gaddamedi: Design and Synthesis of Aromatics through [2+2+2] Cyclotrimerization

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Panchal, Santosh P.; Reddy, Baddigam Kiran; Anand, Venkataramanarao G.: Syntheses and Redox Chemistry of Antiaromatic Core-Modified Isophlorinoids

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Issue 17/2018

García-Morales, Cristina; Echavarren, Antonio M.: From Straightforward Gold(I)-Catalyzed Enyne Cyclizations to more Demanding Intermolecular Reactions of Alkynes with Alkenes

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te Grotenhuis, Colet; de Bruin, Bas: Radical-type Reactions Controlled by Cobalt: From Carbene Radical Reactivity to the Catalytic Intermediacy of Reactive o-Quinodimethanes

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Issue 16/2018

Kuninobu, Yoichiro: Development of Novel C–H Bond Transformations and Their Application to the Synthesis of Organic Functional Molecules

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Barbazanges, Marion; Fensterbank, Louis: The Invention of New Methodologies: An Opportunity for Dating Natural Products

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Issue 15/2018

Kumar, Pradeep; Sharma, Brijesh M.: Proline-Catalyzed Asymmetric α-Amination in the Synthesis of Bioactive Molecules

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Himmel, Hans-Jörg: Guanidines as Reagents in Proton-Coupled Electron-Transfer Reactions and Redox Catalysts

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Issue 14/2018

Wang, Bingbing; Sun, Song; Cheng, Jiang: The n-dig-Cyclization (n = 5, 6) of Alkynes Involving Fixation of CO₂

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Herzon, Seth B.: Emergent Properties of Natural Products

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Issue 13/2018

Zhang, Xiaheng; Yu, Biao: Tackling the Challenge of the Total Synthesis of Periploside A

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Issue 12/2018

Gu, Yueqing; Tan, Ceheng; Gong, Jianxian; Yang, Zhen: Diversity-Oriented Synthesis of Natural Products via Gold-Catalyzed Cascade Reactions

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Issue 11/2018

Zuo, Ziqing; Wen, Huanan; Liu, Guixia; Huang, Zheng: Cobalt-Catalyzed Hydroboration and Borylation of Alkenes and Alkynes

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Issue 10/2018

Kawato, Yuji; Hamashima, Yoshitaka: Enantioselective Bromocyclization of Allylic Amides Mediated by Phosphorus Catalysis

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Issue 09/2018

Abdelraheem, Eman M. M.; Shaabani, Shabnam; Dömling, Alexander: Artificial Macrocycles

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Issue 08/2018

Xie, Xiaoni; Zu, Liansuo: Skeletal Rearrangements as Strategies for the Total Syntheses of Indole Alkaloids

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Issue 07/2018

Chen, Juan; Liu, Bo: Total Synthesis of Natural Terpenoids: Inspired but Not Limited by Biohypothesis

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Issue 06/2018

Jessen, H. J.: The Hitchhiker’s Guide to Organophosphate Chemistry

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Issue 05/2018

Liu, Xiao-Fang; Li, Xiao-Ya; Qiao, Chang; He, Liang-Nian: Transition-Metal-Free Catalysis for the Reductive ­Functionalization of CO₂ with Amines

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Issue 04/2018

Shintani, Ryo: Recent Progress in Catalytic Enantioselective Desymmetrization of Prochiral Organosilanes for the Synthesis of Silicon-Stereogenic Compounds

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Moore, Bradley S.: Asymmetric Alkene and Arene Halofunctionalization Reactions in Meroterpenoid Biosynthesis

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Issue 03/2018

Curti, Claudio; Sartori, Andrea; Battistini, Lucia; Zanardi, Franca: Exploring the Remote Reactivity of π-Extended Carbonyl Compounds: The Vinylogous Alkylidene Malononitrile Activation Strategy

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