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Synthesis 2025; 57(10): 1721-1732
DOI: 10.1055/a-2499-2559
DOI: 10.1055/a-2499-2559
feature
Nickel-Catalyzed Regioselective Access to Dibenzo[c,f][1,2]thiazepine 5,5-Dioxides and Dibenzo[b,e]azepines
T.G. gratefully acknowledges funding from the Science and Engineering Research Board (SERB), India for a TARE fellowship (TAR/2023/000045). S.S.A. is grateful to the Council of Scientific and Industrial Research (CSIR), India for a Junior Research Fellowship (JRF).
Abstract
An effective technique that yields dibenzo[c,f][1,2]thiazepine 5,5-dioxide and dibenzo[b,e]azepine derivatives through nickel-catalyzed regioselective intramolecular acetylene hydroarylation is reported. The developed method proceeds without the need for any additional external ligand. This protocol tolerates different functional groups and furnishes the desired products regioselectively in good to excellent yields.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/a-2499-2559.
- Supporting Information
Publikationsverlauf
Eingereicht: 09. Oktober 2024
Angenommen nach Revision: 09. Dezember 2024
Accepted Manuscript online:
09. Dezember 2024
Artikel online veröffentlicht:
17. Januar 2025
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