A General Synthesis of 3,7-Di(carboxyalkyl)-Functionalized Pyrimidopteridine Photoredox Catalysts

Johannes Fessler; Dao Xuan Huy; Sina Brandt; Tobias Taeufer; Ayla Kruse; Stefan Lochbrunner; Jola Pospech

doi:10.1055/a-2403-2247

Synthesis, Table of Contents

Synthesis 2024; 56(24): 3849-3858
DOI: 10.1055/a-2403-2247

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A General Synthesis of 3,7-Di(carboxyalkyl)-Functionalized Pyrimidopteridine Photoredox Catalysts

Authors

Johannes Fessler

^aLeibniz Institute for Catalysis (LIKAT), Albert-Einstein-Str. 29a, 18059 Rostock, Germany
Dao Xuan Huy

^aLeibniz Institute for Catalysis (LIKAT), Albert-Einstein-Str. 29a, 18059 Rostock, Germany

^bHanoi University of Science and Technology (HUST), School of Chemistry and Life Sciences, Dai Co Viet No. 1, Hanoi, Vietnam
Sina Brandt

^aLeibniz Institute for Catalysis (LIKAT), Albert-Einstein-Str. 29a, 18059 Rostock, Germany
Tobias Taeufer

^aLeibniz Institute for Catalysis (LIKAT), Albert-Einstein-Str. 29a, 18059 Rostock, Germany
Ayla Kruse

^cInstitute of Physics, University of Rostock, Albert-Einstein-Str. 23, 18059 Rostock, Germany
Stefan Lochbrunner

^cInstitute of Physics, University of Rostock, Albert-Einstein-Str. 23, 18059 Rostock, Germany

^dDepartment of Life, Light and Matter (LLM), University of Rostock, Albert-Einstein-Str. 25, 18059 Rostock, Germany
Jola Pospech ∗

^aLeibniz Institute for Catalysis (LIKAT), Albert-Einstein-Str. 29a, 18059 Rostock, Germany

^dDepartment of Life, Light and Matter (LLM), University of Rostock, Albert-Einstein-Str. 25, 18059 Rostock, Germany

Abstract

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Abstract

In this work, the multi-step synthesis of three novel pyrimidopteridine photoredox catalysts is reported. These catalysts contain di(carboxyalkyl)-substitution at the 3- and 7-positions as handles for further synthetic modifications. The catalysts are fully characterized including by photochemical and electrochemical means. Additionally, a catalytic application in the oxidative annulation of 2-phenylbenzoic acid is presented.

Key words

photoredox catalysis - pyridmidopteridines - organic photoredox catalysts - photophysical characterization - amino acid - heterocycles

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References

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Supplementary Material

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