Recent Advances in Radical Reactions of Vinyl Triflates and Their Derivatives

Abstract

Vinyl triflates are valuable precursors for vinyl cations and vinyl carbenes and serve as electrophiles in transition-metal-catalyzed cross-coupling reactions. However, the scope of radical reactions involving vinyl triflates has been very limited until recently. In this short review, we summarize the recent development on two categories of radical reactions involving vinyl triflates, i.e., radical trifluoromethylations and radical non-trifluoromethylations of vinyl triflates.

1 I ntroduction to Vinyl Triflates

2 Earlier Work on Radical Reactions of Vinyl Triflates

3 Radical Trifluoromethylations of Vinyl Triflates and Their Derivatives

4 Radical Non-Trifluoromethylation of Vinyl Triflates

5 Conclusions and Outlook

Key words

radical reactions - trifluoromethylations - vinyl triflates - ketones - alkynes - alkenes

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