Subscribe to RSS
DOI: 10.1055/a-1484-1968
Kolondivertikel und Divertikulitis
Diverticula of the colon: Review of related entities
Divertikel im linksseitigen Kolon sind sehr häufig – zwar meist eine Erscheinung jenseits des 50. Lebensjahres, aber immer häufiger auch bei jüngeren Menschen. Die exakte Diagnose der Divertikulitis muss durch Bildgebung gesichert werden, idealerweise durch eine Darmsonografie und bei offenen Fragen oder präoperativ durch eine Computertomografie. Die Therapie ist bei unkomplizierten Erkrankungen konservativ und bei schweren/komplizierten Verläufen chirurgisch.
Abstract
Diverticulosis, Diverticular Disease, and Diverticulitis, comprising different entities, pose increasing burdens for health care systems. The introduction of new scientific knowledge into daily clinical work is challenging for attending physicians. This review is related to case presentations and currently debated questions are discussed such as definitions: Which entities are meant by the term “Diverticular Disease”, is “uncomplicated symptomatic Diverticular Disease”(SUDD) reality? To classify diverticula related diseases targeted diagnosis including imaging is necessary. The question is ultrasound or computed tomography, or the combination and in which order?
Lastly, open questions of treatment have to be addressed: Outpatient care or hospitalisation, always antibiotics or only in defined situations, relapse prevention, indications to operate upon?
The present review comes along with revised German guidelines, which will be published later this year on S3-level.
Publication History
Article published online:
31 January 2022
© 2022. Thieme. All rights reserved.
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
Literatur
- 1 Leifeld L, Germer CT, Böhm S. et al S3-Leitlinie Divertikelkrankheit/Divertikulitis.. Im Internet (Stand: 8.12.2021): https://www.awmf.org/uploads/tx_szleitlinien/021-020l_S3_Divertikelkrankheit-Divertikulitis_2021-11.pdf
- 2 Lange A, Zeidler J, von der Schulenburg JM. Epidemiologie und Gesundheitsökonomie der Divertikelkrankheit. In: Lammert F, Lynen JansenP, Lerch MM. Hrsg. Weißbuch Gastroenterologie 2020/21. Berlin: De Gruyter; 2019: 70-74 . Im Internet, Open Access (Stand: 03.11.2020): http://www.degruyter.com/view/title/550059
- 3 Schafmayer C, Harrison JW, Buch S. et al. Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms. Gut 2019; 68: 854-865
- 4 Peery AF, Barrett PR, Park D. et al. A high-fiber diet does not protect against asymptomatic diverticulosis. Gastroenterology 2012; 142: 266-272
- 5 Böhm SK, Kruis W. Lifestyle and other risk factors for diverticulitis. Minerva Gastroenterol Dietol 2017; 63: 110-118
- 6 Tursi A, Scarpignato C, Strate LL. et al. Colonic diverticular disease. Nat Rev Dis Primers 2020; 6: 20
- 7 Iannone A, Ruospo M, Wong G. et al. Mesalazine for people with diverticular disease: a systematic review of randomized controlled trials. Can J Gastroenterol Hepatol 2018; 2018: 5437135
- 8 Strate LL, Arden M, Morris AM. Epidemiology, pathophysiology, and treatment of diverticulitis. Gastroenterology 2019; 156: 1282-1298.e1
- 9 Andeweg CS, Berg R, Staal JB. et al. Patient-reported outcomes after conservative or surgical management of recurrent and chronic complaints of diverticulitis: Systematic review and meta-analysis. Clin Gastroenterol Hepatol 2016; 14: 183-190
- 10 van de Wall BJM, Stam MAW, Draaisma WA. et al. Surgery versus conservative management for recurrent and ongoing leftsided diverticulitis (DIRECT trial): an open-label, multicentre, randomised controlled trial. Lancet Gastroenterol Hepatol 2017; 2: 13-22
- 11 Wolff BG, Boostrom SY. Prophylactic resection, uncomplicated diverticulitis, and recurrent diverticulitis. Dig Dis 2012; 30: 108-113
- 12 Zuckerman GR, Prakash C. Acute lower intestinal bleeding. Part II: etiology, therapy, and outcomes. Gastrointest Endosc 1999; 49: 228-238
- 13 Jensen DM, Machicado GA, Jutabha R. et al. Urgent colonoscopy for the diagnosis and treatment of severe diverticular hemorrhage. N Engl J Med 2000; 342: 78-82